NAD

nicotinamide nucleotide adenylyltransferase 1 ; Mus musculus







39 Article(s)
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1 34699038 NNMT is induced dynamically during beige adipogenesis in adipose tissues depot-specific manner. 2022 Feb 1
2 34750622 Reduced nuclear NAD+ drives DNA damage and subsequent immune activation in the retina. 2022 May 4 5
3 35114390 NMNAT2 is downregulated in glaucomatous RGCs, and RGC-specific gene therapy rescues neurodegeneration and visual function. 2022 Apr 6 1
4 33709122 Mutant Nmnat1 leads to a retina-specific decrease of NAD+ accompanied by increased poly(ADP-ribose) in a mouse model of NMNAT1-associated retinal degeneration. 2021 May 17 4
5 34314389 Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1. 2021 Sep 8 4
6 34878972 Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons. 2021 Dec 8 2
7 32278117 Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction. 2020 Jun 2
8 32822587 Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis. 2020 Sep 17 1
9 29175372 NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy. 2018 Feb 26 1
10 29674119 NMNAT1 E257K variant, associated with Leber Congenital Amaurosis (LCA9), causes a mild retinal degeneration phenotype. 2018 Aug 2
11 30195617 Nicotinamide riboside induces a thermogenic response in lean mice. 2018 Oct 15 1
12 30787047 Benefits of Enhancing Nicotinamide Adenine Dinucleotide Levels in Damaged or Diseased Nerve Cells. 2018 1
13 28209901 Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. 2017 Feb 17 1
14 27184051 Nmnat 1: a Security Guard of Retinal Ganglion Cells (RGCs) in Response to High Glucose Stress. 2016 2
15 27207593 Mouse Models of NMNAT1-Leber Congenital Amaurosis (LCA9) Recapitulate Key Features of the Human Disease. 2016 Jul 2
16 27425894 Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia. 2016 Nov 2
17 27735788 NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion. 2016 Oct 13 3
18 27783719 Nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi (TcNMNAT): a cytosol protein target for serine kinases. 2016 Nov 1
19 25841561 Nicotinamide Mononucleotide Adenylyltransferase 1 Protects Neural Cells Against Ischemic Injury in Primary Cultured Neuronal Cells and Mouse Brain with Ischemic Stroke Through AMP-Activated Protein Kinase Activation. 2015 Jun 2
20 23891603 Mitigation of gamma-radiation induced abasic sites in genomic DNA by dietary nicotinamide supplementation: metabolic up-regulation of NAD(+) biosynthesis. 2013 Sep 1
21 23892229 Maintaining energy homeostasis is an essential component of Wld(S)-mediated axon protection. 2013 Nov 2
22 22315973 WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity. 2012 Feb 8 1
23 22425157 WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering. 2012 Apr 10 1
24 23226106 The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. 2012 2
25 23300904 Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues. 2012 1
26 21615689 Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration. 2011 Aug 2
27 21998399 WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis. 2011 Dec 1
28 22058226 Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death. 2011 Nov 22 2
29 22313312 Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5'-mononucleotide adenylyltransferase-2. 2011 Nov 4
30 20117162 Axon degeneration: Mechanisms and implications of a distinct program from cell death. 2010 Mar 1
31 20445064 Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals. 2010 May 5 1
32 21203970 Wld(S), Nmnats and axon degeneration--progress in the past two decades. 2010 Mar 2
33 19237596 Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice. 2009 Feb 23 1
34 19372760 NAD and axon degeneration: from the Wlds gene to neurochemistry. 2009 Jan-Mar 1
35 19439605 Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration. 2009 May 13 2
36 19458223 Transgenic mice expressing the Nmnat1 protein manifest robust delay in axonal degeneration in vivo. 2009 May 20 1
37 16772165 Tracking in the Wlds--the hunting of the SIRT and the luring of the Draper. 2006 Jun 15 4
38 16043516 A local mechanism mediates NAD-dependent protection of axon degeneration. 2005 Aug 1 2
39 9328141 Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: effects on NAD metabolism and DNA repair. 1997 3