Cyclosporine

peptidylprolyl isomerase D ; Homo sapiens







33 Article(s)
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1 31759087 A novel class of cardioprotective small-molecule PTP inhibitors. 2020 Jan 4
2 31213546 Persistence of the permeability transition pore in human mitochondria devoid of an assembled ATP synthase. 2019 Jun 25 1
3 28273124 Blockade of cyclophilin D rescues dexamethasone-induced oxidative stress in gingival tissue. 2017 3
4 28913661 Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction. 2017 Oct 1
5 29029404 Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells. 2017 Sep 12 2
6 27103440 AICAR induces AMPK-independent programmed necrosis in prostate cancer cells. 2016 May 27 1
7 26858893 Synergistic Effects of Calcineurin Inhibitors and Steroids on Steroid Sensitivity of Peripheral Blood Mononuclear Cells. 2015 Feb 8 2
8 24915078 High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules. 2014 Jun 2
9 23220213 Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes. 2013 Mar 10 2
10 23242346 Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death. 2013 Feb 1
11 22659400 Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D. 2012 Sep 1
12 22869602 Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore. 2012 Nov 1
13 21121808 Cyclophilin D-sensitive mitochondrial permeability transition in adult human brain and liver mitochondria. 2011 Jan 1
14 21311961 Influence of aging on membrane permeability transition in brain mitochondria. 2011 Feb 1
15 21341336 Corosolic acid triggers mitochondria and caspase-dependent apoptotic cell death in osteosarcoma MG-63 cells. 2011 Sep 1
16 20023700 FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A. 2010 Mar 18 3
17 24900244 Facile synthesis of a fluorescent cyclosporin a analogue to study cyclophilin 40 and cyclophilin 18 ligands. 2010 Dec 9 2
18 19187006 Different redox states in malignant and nonmalignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol. 2009 May 1
19 19228691 Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect. 2009 Apr 10 4
20 19741014 Regulation of the mitochondrial permeability transition in kidney proximal tubules and its alteration during hypoxia-reoxygenation. 2009 Dec 2
21 18076075 Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96-A resolution. 2008 Mar 1
22 16675492 Muscle denervation promotes opening of the permeability transition pore and increases the expression of cyclophilin D. 2006 Jul 1 2
23 15233627 Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis. 2004 Oct 1 1
24 12022945 Mitochondrial intermembrane junctional complexes and their involvement in cell death. 2002 Feb-Mar 1
25 12077116 Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization. 2002 Aug 23 6
26 9658403 Calcium/calmodulin kinase inhibitors and immunosuppressant macrolides rapamycin and FK506 inhibit progestin- and glucocorticosteroid receptor-mediated transcription in human breast cancer T47D cells. 1998 Jul 1
27 9659917 Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism. 1998 Jan 1
28 9195923 Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin. 1997 Jun 27 1
29 9237665 Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. 1997 Jun 30 1
30 8602846 Cyclosporin A potentiates estradiol-induced expression of the cathepsin D gene in MCF7 breast cancer cells. 1996 Mar 7 1
31 7717993 Cyclophilin-40: evidence for a dimeric complex with hsp90. 1995 Apr 1 1
32 7744028 Expression of human cyclophilin-40 and the effect of the His141-->Trp mutation on catalysis and cyclosporin A binding. 1995 Apr 1 3
33 8509368 Cyclophilin-40, a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterization. 1993 Jun 15 6