Morphine

toll-like receptor 4 ; Rattus norvegicus







28 Article(s)
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1 32533604 Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists. 2022 Jan 2
2 32926257 Morphine and Fentanyl Repeated Administration Induces Different Levels of NLRP3-Dependent Pyroptosis in the Dorsal Raphe Nucleus of Male Rats via Cell-Specific Activation of TLR4 and Opioid Receptors. 2022 Apr 2
3 33341652 Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats. 2021 Feb 2
4 34142718 Acute morphine blocks spinal respiratory motor plasticity via long-latency mechanisms that require toll-like receptor 4 signalling. 2021 Aug 6
5 31879851 Chronic morphine-mediated upregulation of high mobility group box 1 in the spinal cord contributes to analgesic tolerance and hyperalgesia in rats. 2020 Apr 5
6 32131713 MicroRNA-146a attenuates the development of morphine analgesic tolerance in a rat model. 2020 May 3
7 30487293 Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats. 2019 Feb 1
8 30660614 Dopamine D1 receptor agonist treatment alleviates morphine-exposure-induced learning and memory impairments. 2019 May 15 1
9 31209174 Role of Nociceptor Toll-like Receptor 4 (TLR4) in Opioid-Induced Hyperalgesia and Hyperalgesic Priming. 2019 Aug 14 5
10 31646595 Morphine alleviates myocardial ischemia/reperfusion injury in rats by inhibiting TLR4/NF-κB signaling pathway. 2019 Oct 4
11 28860068 Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats. 2018 Aug 1
12 29199028 Sex-dependent influences of morphine and its metabolites on pain sensitivity in the rat. 2018 Apr 1 3
13 29310498 Inhibition of toll-like receptor 4 alleviates hyperalgesia induced by acute dural inflammation in experimental migraine. 2018 Jan-Dec 2
14 29723521 MicroRNA-124 and microRNA-146a both attenuate persistent neuropathic pain induced by morphine in male rats. 2018 Aug 1 1
15 27461080 Toll-like Receptor 4 Mediates Morphine-Induced Neuroinflammation and Tolerance via Soluble Tumor Necrosis Factor Signaling. 2017 Feb 2
16 28219988 Sex Differences in Microglia Activity within the Periaqueductal Gray of the Rat: A Potential Mechanism Driving the Dimorphic Effects of Morphine. 2017 Mar 22 9
17 28827130 Activation of TLR4/STAT3 signaling in VTA contributes to the acquisition and maintenance of morphine-induced conditioned place preference. 2017 Sep 29 7
18 26962463 Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model. 2016 1
19 27519154 Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury. 2016 Nov 6
20 28306133 Injection of Toll-like receptor 4 siRNA into the ventrolateral periaqueductal gray attenuates withdrawal syndrome in morphine-dependent rats. 2016 Dec 1 3
21 24121451 Role of phosphodiesterase inhibitor Ibudilast in morphine-induced hippocampal injury. 2014 Jul 2
22 25182346 Chronic morphine treatment increased the expression of myeloid differentiation primary response protein 88 in rat spinal cord. 2014 Dec 1
23 25241065 Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. 2014 Nov 7 4
24 25446875 Toll-like receptor 4-mediated nuclear factor-κB activation in spinal cord contributes to chronic morphine-induced analgesic tolerance and hyperalgesia in rats. 2014 Dec 4
25 23325235 Adolescent morphine exposure affects long-term microglial function and later-life relapse liability in a model of addiction. 2013 Jan 16 11
26 24089500 Blockade of Toll-like receptor 4 attenuates morphine tolerance and facilitates the pain relieving properties of morphine. 2013 Oct 2 7
27 22895704 Opioid activation of toll-like receptor 4 contributes to drug reinforcement. 2012 Aug 15 4
28 19788917 Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. 2009 Dec 29 1