ruxolitinib

Janus kinase 1 ; Homo sapiens







381 Article(s)
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1 33693561 Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults With Human Immunodeficiency Virus. 2022 Jan 7 1
2 33795598 Ruxolitinib for the Treatment of Chronic GVHD and Overlap Syndrome in Children and Young Adults. 2022 Feb 1 1
3 34074166 Ruxolitinib is an alternative to etoposide for patient with hemophagocytic lymphohistiocytosis complicated by acute renal injury: A case report. 2022 Jan 1
4 34097573 Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function. 2022 Apr 3 1
5 34423448 Leukocytoclastic vasculitis due to ruxolitinib treatment: A rare adverse effect. 2022 Apr 1
6 34521299 Adherence to ruxolitinib, an oral JAK1/2 inhibitor, in patients with myelofibrosis: interim analysis from an Italian, prospective cohort study (ROMEI). 2022 Jan 2
7 34536415 Early-onset pulmonary and cutaneous vasculitis driven by constitutively active SRC-family kinase HCK. 2022 Apr 1
8 34655610 Vitiligo Skin T Cells Are Prone to Produce Type 1 and Type 2 Cytokines to Induce Melanocyte Dysfunction and Epidermal Inflammatory Response Through Jak Signaling. 2022 Apr 1
9 34694880 Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Coadministered Ruxolitinib and Artemether-Lumefantrine in Healthy Adults. 2022 Jan 18 1
10 35131254 Ruxolitinib Cream in the Treatment of Cutaneous Lichen Planus: A Prospective, Open-Label Study. 2022 Feb 5 1
11 35131544 Propionate induces cross-tolerance to TLR1/2 and TLR4 agonists in an IFIT-dependent manner. 2022 Mar 1
12 35186752 FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma. 2022 1
13 35266648 Interferon-gamma induces melanogenesis via post-translational regulation of tyrosinase. 2022 May 1
14 35337171 New Applications of JAK/STAT Inhibitors in Pediatrics: Current Use of Ruxolitinib. 2022 Mar 19 1
15 35363892 Peripheral blasts are associated with responses to ruxolitinib and outcomes in patients with chronic-phase myelofibrosis. 2022 Jul 1 2
16 35368221 A Maximum-Use Trial of Ruxolitinib Cream in Adolescents and Adults with Atopic Dermatitis. 2022 May 2
17 35368384 Ruxolitinib in addition to standard of care for the treatment of patients admitted to hospital with COVID-19 (RUXCOVID): a randomised, double-blind, placebo-controlled, phase 3 trial. 2022 May 2
18 35371054 Indoleamine 2, 3-Dioxygenase 1 Mediates Survival Signals in Chronic Lymphocytic Leukemia via Kynurenine/Aryl Hydrocarbon Receptor-Mediated MCL1 Modulation. 2022 3
19 35382859 Ruxolitinib suppresses liver fibrosis progression and accelerates fibrosis reversal via selectively targeting Janus kinase 1/2. 2022 Apr 5 1
20 35437311 Safety analysis of patients who received ruxolitinib for steroid-refractory acute or chronic graft-versus-host disease in an expanded access program. 2022 Jun 1
21 35443042 Recent FDA Approvals in the Treatment of Graft-Versus-Host Disease. 2022 Apr 20 1
22 35507130 Ex vivo effect of JAK inhibition on JAK-STAT1 pathway hyperactivation in patients with dominant-negative STAT3 mutations. 2022 May 4 1
23 35595725 GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes. 2022 May 20 1
24 35597252 Ruxolitinib versus best available therapy in inadequately controlled polycythaemia vera without splenomegaly (RESPONSE-2): 5-year follow up of a randomised, phase 3b study. 2022 May 18 1
25 35604239 Ruxolitinib, a JAK1/2 Inhibitor as Treatment for Paraneoplastic Pemphigus: A Case Report. 2022 Jun 9 1
26 35635540 Development and application of an LC-MS/MS method for pharmacokinetic study of ruxolitinib in children with hemophagocytic lymphohistiocytosis. 2022 Jun 16 2
27 32201152 Reactivation of tuberculosis following ruxolitinib therapy for primary myelofibrosis: Case series and literature review. 2021 Sep 1
28 32732367 A pilot study of ruxolitinib as a front-line therapy for 12 children with secondary hemophagocytic lymphohistiocytosis. 2021 Jul 1 1
29 32814839 Compassionate use of JAK1/2 inhibitor ruxolitinib for severe COVID-19: a prospective observational study. 2021 Apr 2
30 32981124 Efficacy and feasibility of ruxolitinib in chronic steroid-refractory GVHD in a pediatric intestine transplant. 2021 May 1
31 33129109 Enhanced efficacy of JAK1 inhibitor with mTORC1/C2 targeting in smoldering/chronic adult T cell leukemia. 2021 Jan 1
32 33222197 Second primary malignancy in myelofibrosis patients treated with ruxolitinib. 2021 Apr 2
33 33338537 JAK1/2 inhibition impairs the development and function of inflammatory dendritic epidermal cells in atopic dermatitis. 2021 Jun 1
34 33465556 Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3. 2021 Feb 1
35 33502484 Evaluation of Ruxolitinib for Steroid-Refractory Chronic Graft-vs-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation. 2021 Jan 4 1
36 33509955 Phospholipase A2 receptor 1 promotes lung cell senescence and emphysema in obstructive lung disease. 2021 Aug 1
37 33517393 Mosaic IL6ST variant inducing constitutive GP130 cytokine receptor signaling as a cause of neonatal onset immunodeficiency with autoinflammation and dysmorphy. 2021 Apr 26 1
38 33523540 Ruxolitinib as adjunctive therapy for secondary hemophagocytic lymphohistiocytosis: A case series. 2021 May 1
39 33534941 Ruxolitinib inhibits poly(I:C) and type 2 cytokines-induced CCL5 production in bronchial epithelial cells: A potential therapeutic agent for severe eosinophilic asthma. 2021 Jun 1
40 33585999 Phase I study of JAK1/2 inhibitor ruxolitinib with weekly paclitaxel for the treatment of HER2-negative metastatic breast cancer. 2021 May 2
41 33598678 BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia. 2021 Jun 24 2
42 33694335 Successful management of familial hemophagocytic lymphohistiocytosis by the JAK 1/2 inhibitor ruxolitinib. 2021 Jun 1
43 33747209 Ruxolitinib induces apoptosis of human colorectal cancer cells by downregulating the JAK1/2-STAT1-Mcl-1 axis. 2021 May 3
44 33782031 Therapeutic Efficacy of Combined JAK1/2, Pan-PIM, and CDK4/6 Inhibition in Myeloproliferative Neoplasms. 2021 Jun 15 1
45 33792103 Contemporary Risk Stratification and Treatment of Chronic Myelomonocytic Leukemia. 2021 May 1
46 33827897 SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. 2021 Apr 7 1
47 33830087 Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata. 2021 Apr 8 1
48 33845867 Multi-arm Trial of Inflammatory Signal Inhibitors (MATIS) for hospitalised patients with mild or moderate COVID-19 pneumonia: a structured summary of a study protocol for a randomised controlled trial. 2021 Apr 12 2
49 33954282 Pharmacological Inhibition of Insulin Growth Factor-1 Receptor (IGF-1R) Alone or in Combination With Ruxolitinib Shows Therapeutic Efficacy in Preclinical Myeloproliferative Neoplasm Models. 2021 May 1
50 33965175 Ruxolitinib Inhibits IFNγ Licensing of Human Bone Marrow Derived Mesenchymal Stromal Cells. 2021 May 2