pyrazole

cytochrome P450, family 2, subfamily e, polypeptide 1 ; Mus musculus







17 Article(s)
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Title
Pub. Year
#Total Relationships
1 27653210 An improved in vitro method for screening toxin and medicine targeting CYP2E1. 2016 Oct 2
2 23400918 Nrf2 and antioxidant defense against CYP2E1 toxicity. 2013 1
3 22490042 Peroxiredoxin III and sulfiredoxin together protect mice from pyrazole-induced oxidative liver injury. 2012 Nov 15 3
4 21748763 Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice. 2011 Nov 3
5 19063961 Role of nitric oxide and nuclear factor-kappaB in the CYP2E1 potentiation of tumor necrosis factor alpha hepatotoxicity in mice. 2009 Feb 15 2
6 19477265 Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase. 2009 Sep 1 1
7 19671018 Nrf2 and antioxidant defense against CYP2E1 toxicity. 2009 Oct 2
8 18721845 Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency. 2008 Oct 30 2
9 17446309 S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury. 2007 Jul 2
10 17538970 Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice. 2007 Jun 2
11 16373529 S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice. 2006 Apr 1
12 16374848 Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1. 2006 Jan 1
13 16799984 Enhancement by pyrazole of lipopolysaccharide-induced liver injury in mice: role of cytochrome P450 2E1 and 2A5. 2006 Jul 7
14 16958665 Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. 2006 Oct 1
15 16025513 Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice. 2005 Aug 2
16 11803702 NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice. 1999 Aug 1
17 9698299 Differential xenobiotic induction of CYP2A5 in mouse liver, kidney, lung, and olfactory mucosa. 1998 Aug 2