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ATP binding cassette subfamily C member 2 ; Homo sapiens







39 Article(s)
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1 29247669 Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models. 2018 Mar 1
2 30051196 Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip. 2018 Jul 26 1
3 28677116 DS-8201a, a new HER2-targeting antibody-drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2-positive gastric cancer T-DM1 resistance. 2017 Oct 15 1
4 28871225 Exposure Characteristics of the Analogous β-Carboline Alkaloids Harmaline and Harmine Based on the Efflux Transporter of Multidrug Resistance Protein 2. 2017 1
5 29299132 Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters. 2017 Dec 15 1
6 25761590 Transport of trans-tiliroside (kaempferol-3-β-D-(6"-p-coumaroyl-glucopyranoside) and related flavonoids across Caco-2 cells, as a model of absorption and metabolism in the small intestine. 2015 1
7 25801004 MK571 inhibits phase-2 conjugation of flavonols by Caco-2/TC7 cells, but does not specifically inhibit their apical efflux. 2015 Jun 1 4
8 26131551 Multidrug Resistance-Associated Protein 2 (MRP2) Mediated Transport of Oxaliplatin-Derived Platinum in Membrane Vesicles. 2015 2
9 26231439 Intestinal absorption mechanisms of MTBH, a novel hesperetin derivative, in Caco-2 cells, and potential involvement of monocarboxylate transporter 1 and multidrug resistance protein 2. 2015 Oct 12 1
10 24525098 Transport characteristics of isorhamnetin across intestinal Caco-2 cell monolayers and the effects of transporters on it. 2014 Apr 1
11 24861759 Intestinal transport of sophocarpine across the Caco-2 cell monolayer model and quantification by LC/MS. 2014 Jun 1
12 24913304 A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels. 2014 Oct 1
13 23020787 Transport of gemifloxacin, a 4th generation quinolone antibiotic, in the Caco-2 and engineered MDCKII cells, and potential involvement of efflux transporters in the intestinal absorption of the drug. 2013 Apr 1
14 23420099 Factors affecting the sensitivity of human-derived esophageal carcinoma cell lines to 5-fluorouracil and cisplatin. 2013 Feb 1
15 23562926 Transcellular transport of aconitine across human intestinal Caco-2 cells. 2013 Jul 2
16 22359351 Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: a strategy to assess the interaction of a new chemical entity with P-gp, BCRP, and MRP2. 2012 May 1
17 22775210 Characterization of efflux transport of the PDE5 inhibitors, vardenafil and sildenafil. 2012 Aug 1
18 22982073 Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin. 2012 Dec 15 1
19 21206135 Preclinical pharmacokinetics of PDE-310, a novel PDE4 inhibitor. 2011 1
20 21968553 Photoaffinity labeling of the multidrug resistance protein 2 (ABCC2/cMOAT) with a photoreactive analog of LTC(4). 2011 4
21 19201990 Localization of multidrug resistance-associated protein 2 in the nonpigmented ciliary epithelium of the eye. 2009 May 1
22 18405608 [Absorption and transport of 6 coumarins isolated from the roots of Angelica pubescens f. biserrata in human Caco-2 cell monolayer model]. 2008 Apr 1
23 18509604 Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies. 2008 Aug 1
24 18612942 In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes. 2008 Aug 1
25 18718123 Presence or absence of a gallate moiety on catechins affects their cellular transport. 2008 Sep 1
26 19020751 Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer. 2008 Dec 2
27 17276588 Interaction between CD44 and hyaluronate induces chemoresistance in non-small cell lung cancer cell. 2007 Jul 18 2
28 17543436 Epithelial transport of deoxynivalenol: involvement of human P-glycoprotein (ABCB1) and multidrug resistance-associated protein 2 (ABCC2). 2007 Oct 1
29 17855498 Transport of a fluorescent cAMP analog in teleost proximal tubules. 2007 Dec 1
30 16244858 Ochratoxin A secretion by ATP-dependent membrane transporters in Caco-2 cells. 2006 May 1
31 15686436 Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells. 2005 Feb 9 1
32 15729621 Inhibitory activity of a green tea extract and some of its constituents on multidrug resistance-associated protein 2 functionality. 2005 Feb 1
33 16316932 Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport. 2005 Jul 1
34 11877335 Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells. 2002 Mar 1
35 11697467 Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2. 2001 Oct 1
36 11713653 Human intestinal cell monolayers are preferentially sensitive to disruption of barrier function from basolateral exposure to cholic acid: correlation with membrane transport and transepithelial secretion. 2001 Nov 1
37 10760098 ATP-dependent para-aminohippurate transport by apical multidrug resistance protein MRP2. 2000 Apr 1
38 10424761 Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2. 1999 Aug 1 1
39 10440570 Transport of genistein-7-glucoside by human intestinal CACO-2 cells: potential role for MRP2. 1999 Jan 1