Glucuronides

ATP binding cassette subfamily C member 2 ; Homo sapiens







44 Article(s)
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1 34554580 Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling. 2022 Mar 1
2 34169529 Association of ABCC2 Haplotypes to Mycophenolic Acid Pharmacokinetics in Stable Kidney Transplant Recipients. 2021 Dec 2
3 34862251 Mechanistic study on the species differences in excretion pathway of HR011303 in human and rats. 2021 Dec 3 2
4 31704245 Human efflux transport of testosterone, epitestosterone and other androgen glucuronides. 2020 Mar 3
5 30959153 Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney. 2019 Jul 3
6 29175180 Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP. 2018 Apr 1
7 28850245 Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport. 2017 Oct 2 1
8 26500117 Akt2-Dependent Phosphorylation of Radixin in Regulation of Mrp-2 Trafficking in WIF-B Cells. 2016 Feb 1
9 26659924 Stereoselective Inhibition of Methotrexate Excretion by Glucuronides of Nonsteroidal Anti-inflammatory Drugs via Multidrug Resistance Proteins 2 and 4. 2016 Feb 1
10 25204339 Mechanisms underlying benign and reversible unconjugated hyperbilirubinemia observed with faldaprevir administration in hepatitis C virus patients. 2014 Nov 1
11 23387445 Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line. 2013 May 1
12 23462933 Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis. 2013 Sep 1
13 23750830 Evaluating the in vitro inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in predicting drug-induced hyperbilirubinemia. 2013 Aug 5 1
14 21923755 Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells. 2012 Mar 1
15 22245901 4-Phenylbutyrate modulates ubiquitination of hepatocanalicular MRP2 and reduces serum total bilirubin concentration. 2012 May 3
16 22683417 Influence of hepatic and intestinal efflux transporters and their genetic variants on the pharmacokinetics and pharmacodynamics of raloxifene in osteoporosis treatment. 2012 Oct 1
17 22982073 Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin. 2012 Dec 15 1
18 25400909 Mutual interactions between flavonoids and enzymatic and transporter elements responsible for flavonoid disposition via phase II metabolic pathways. 2012 Sep 21 1
19 21687948 'Genetic profiling' and ovarian cancer therapy (review). 2011 Sep-Oct 1
20 21691255 Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2). 2011 Aug 3
21 21860343 Nonsteroidal anti-inflammatory drugs may reduce enterohepatic recirculation of mycophenolic acid in patients with childhood-onset systemic lupus erythematosus. 2011 Oct 2
22 19566819 Multidrug resistance-associated proteins and implications in drug development. 2010 Jan 1
23 20082599 ABCC2/Abcc2: a multispecific transporter with dominant excretory functions. 2010 Aug 2
24 19588995 Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells. 2009 Nov-Dec 3
25 18460254 Dubin-Johnson syndrome. 2008 Mar 1
26 18597651 Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers. 2008 Jul 1
27 17108237 Human multidrug resistance protein 2 transports the therapeutic bile salt tauroursodeoxycholate. 2007 Feb 2
28 17227625 Efflux of baicalin, a flavone glucuronide of Scutellariae Radix, on Caco-2 cells through multidrug resistance-associated protein 2. 2007 Jan 1
29 17578901 Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices. 2007 Sep 1
30 17828742 Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (-/-) mice. 2007 Dec 2
31 16842856 Intestinal tract injury by drugs: Importance of metabolite delivery by yellow bile road. 2006 Dec 2
32 15795089 Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites. 2005 May 16 1
33 15846474 Treatment of hyperbilirubinemia in Eisai hyperbilirubinemic rat by transfecting human MRP2/ABCC2 gene. 2005 Apr 3
34 14643890 Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione. 2004 Feb 2
35 12524417 Antidepressant induced cholestasis: hepatocellular redistribution of multidrug resistant protein (MRP2). 2003 Feb 1
36 12130697 Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition. 2002 Aug 3
37 12395335 Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome. 2002 Nov 2
38 12483266 Hepatobiliary transport of bile acids and organic anions. 2002 2
39 11124235 Correction to "Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan" 2001 Jan 2
40 10944550 A family of drug transporters: the multidrug resistance-associated proteins. 2000 Aug 16 1
41 11023036 Recent advances in bilirubin metabolism research: the molecular mechanism of hepatocyte bilirubin transport and its clinical relevance. 2000 4
42 9794919 Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B. 1998 Nov 4
43 9355767 ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. 1997 Oct 1 5
44 9377473 Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2. 1997 Aug 1