2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide

midkine ; Mus musculus







12 Article(s)
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Pub. Year
#Total Relationships
1 32304723 Antiviral efficacy against influenza virus and pharmacokinetic analysis of a novel MEK-inhibitor, ATR-002, in cell culture and in the mouse model. 2020 Jun 1
2 29793021 Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation. 2018 Oct 1
3 27913296 Regulation of skeletal muscle insulin-stimulated signaling through the MEK-REDD1-mTOR axis. 2017 Jan 22 1
4 23250956 Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma. 2013 Jan 2 1
5 23501104 Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models. 2013 Apr 19 1
6 23954471 The protective action of ketanserin against lipopolysaccharide-induced shock in mice is mediated by inhibiting inducible NO synthase expression via the MEK/ERK pathway. 2013 Dec 1
7 21501342 SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation. 2011 May 1
8 18614619 Reduction of chronic allograft nephropathy by inhibition of extracellular signal-regulated kinase 1 and 2 signaling. 2008 Sep 1
9 17907188 Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms. 2007 Oct 2
10 15967111 A role for K-ras in conferring resistance to the MEK inhibitor, CI-1040. 2005 Apr 3
11 16267021 Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells. 2005 Nov 1 1
12 15171791 Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure. 2004 Jun 1 3