| 1 |
34108651 | Role of TRPM2 in brain tumours and potential as a drug target. | 2022 Apr |
4 |
| 2 |
34989943 | A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol. | 2022 Mar |
3 |
| 3 |
35366734 | Amantadine Attenuated Hypoxia-Induced Mitochondrial Oxidative Neurotoxicity, Apoptosis, and Inflammation via the Inhibition of TRPM2 and TRPV4 Channels. | 2022 Jun |
1 |
| 4 |
33389617 | Involvement of TRPM2 Channel on Hypoxia-Induced Oxidative Injury, Inflammation, and Cell Death in Retinal Pigment Epithelial Cells: Modulator Action of Selenium Nanoparticles. | 2021 Apr |
2 |
| 5 |
33544179 | Bevacizumab induces oxidative cytotoxicity and apoptosis via TRPM2 channel activation in retinal pigment epithelial cells: Protective role of glutathione. | 2021 Jun |
1 |
| 6 |
33925466 | Two Decades of Evolution of Our Understanding of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel. | 2021 Apr 27 |
1 |
| 7 |
34299254 | The Role of TRPM2 in Endothelial Function and Dysfunction. | 2021 Jul 16 |
2 |
| 8 |
34788616 | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. | 2021 Nov 16 |
2 |
| 9 |
31646518 | Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores. | 2020 |
1 |
| 10 |
31934327 | Synthesis of phosphonoacetate analogues of the second messenger adenosine 5'-diphosphate ribose (ADPR). | 2020 |
1 |
| 11 |
32019426 | Curcumin diminishes cisplatin-induced apoptosis and mitochondrial oxidative stress through inhibition of TRPM2 channel signaling pathway in mouse optic nerve. | 2020 Apr |
5 |
| 12 |
32036619 | Microglial NMDA receptors drive pro-inflammatory responses via PARP-1/TRMP2 signaling. | 2020 Jul |
4 |
| 13 |
32046066 | One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates with Autism Spectrum Disorder in a Japanese Population. | 2020 Feb 7 |
4 |
| 14 |
32296107 | Resveratrol attenuates hypoxia-induced neuronal cell death, inflammation and mitochondrial oxidative stress by modulation of TRPM2 channel. | 2020 Apr 15 |
2 |
| 15 |
32646271 | Clostridium botulinum neurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells. | 2020 Dec |
1 |
| 16 |
32871135 | Hyperthermia synergistically enhances cancer cell death by plasma-activated acetated Ringer's solution. | 2020 Oct 30 |
2 |
| 17 |
30191993 | 8-Br-cADPR, a TRPM2 ion channel antagonist, inhibits renal ischemia-reperfusion injury. | 2019 Apr |
1 |
| 18 |
30925291 | TRPM2 in Cancer. | 2019 Jun |
4 |
| 19 |
30965058 | Pharmacology of JNJ-28583113: A novel TRPM2 antagonist. | 2019 Jun 15 |
2 |
| 20 |
31144442 | Mechanism of TRPM2 channel gating revealed by cryo-EM. | 2019 Sep |
4 |
| 21 |
31455864 | Albumin evokes Ca2+-induced cell oxidative stress and apoptosis through TRPM2 channel in renal collecting duct cells reduced by curcumin. | 2019 Aug 27 |
1 |
| 22 |
31513012 | Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel. | 2019 Sep 12 |
2 |
| 23 |
29034580 | Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues. | 2018 Feb |
1 |
| 24 |
29745897 | Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation. | 2018 May 10 |
1 |
| 25 |
30190133 | The ADP-ribose reactive NUDIX hydrolase isoforms can modulate HIF-1α in cancer cells. | 2018 Sep 26 |
1 |
| 26 |
28108595 | Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2. | 2017 Feb |
2 |
| 27 |
28515263 | Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349. | 2017 Jun 16 |
1 |
| 28 |
28671679 | 2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist. | 2017 Sep |
2 |
| 29 |
26420388 | TRPM2 protects against tissue damage following oxidative stress and ischaemia-reperfusion. | 2016 Aug 1 |
1 |
| 30 |
26969190 | Sensing of redox status by TRP channels. | 2016 Aug |
1 |
| 31 |
27333281 | ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain. | 2016 |
8 |
| 32 |
25620041 | Functional characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells. | 2015 Jan 26 |
1 |
| 33 |
26009185 | Designer small molecules to target calcium signalling. | 2015 Jun |
2 |
| 34 |
24492610 | TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria. | 2014 Mar 14 |
1 |
| 35 |
24954469 | PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca(2+)-permeable AMPA receptors. | 2014 Oct |
1 |
| 36 |
24961969 | TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters). | 2014 |
1 |
| 37 |
23957292 | Lys1110 of TRPM2 is critical for channel activation. | 2013 Nov 1 |
2 |
| 38 |
24009611 | Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling. | 2013 |
1 |
| 39 |
24304219 | Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists. | 2013 Dec 27 |
3 |
| 40 |
22219339 | The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation. | 2012 Mar 1 |
1 |
| 41 |
22226147 | The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death. | 2012 Feb |
2 |
| 42 |
22493272 | Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions. | 2012 Apr 24 |
2 |
| 43 |
22847436 | Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents. | 2012 Aug 14 |
1 |
| 44 |
23086953 | The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. | 2012 Nov 30 |
1 |
| 45 |
23236422 | A cell permeable NPE caged ADP-ribose for studying TRPM2. | 2012 |
2 |
| 46 |
20878536 | Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2+ fluxes in oxidative cell death. | 2011 Apr |
2 |
| 47 |
20194125 | The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification. | 2010 Apr 15 |
1 |
| 48 |
20587417 | Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8. | 2010 Aug 27 |
1 |
| 49 |
18521748 | Role of an N-terminal splice segment in the activation of the cation channel TRPM2 by ADP-ribose and hydrogen peroxide. | 2009 Feb |
1 |
| 50 |
19171771 | Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate. | 2009 Feb |
1 |