| 1 |
34874016 | mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats. | 2022 Jan 31 |
1 |
| 2 |
35044284 | RAS protein activator like 2 promotes the proliferation and migration of pulmonary artery smooth muscle cell through AKT/mammalian target of Rapamycin complex 1 pathway in pulmonary hypertension. | 2022 Feb |
1 |
| 3 |
35428493 | Rapamycin induces autophagy and apoptosis in Kaposiform hemangioendothelioma primary cells in vitro. | 2022 Jul |
1 |
| 4 |
33189285 | Acetate regulates milk fat synthesis through the mammalian target of rapamycin/eukaryotic initiation factor 4E signaling pathway in bovine mammary epithelial cells. | 2021 Jan |
1 |
| 5 |
33549024 | Effects and potential mechanisms of rapamycin on MPTP-induced acute Parkinson's disease in mice. | 2021 Mar |
1 |
| 6 |
33660929 | Effect of mechanistic/mammalian target of rapamycin complex 1 on mitochondrial dynamics during skeletal muscle hypertrophy. | 2021 Mar |
1 |
| 7 |
33773987 | Long-Term Effects of Sirolimus on Human Skin TSC2-Null Fibroblast‒Like Cells. | 2021 Sep |
1 |
| 8 |
33852892 | The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1. | 2021 Jun 3 |
1 |
| 9 |
33865602 | Overexpression Prox1 in HemECs resembles Kaposiform hemangioendothelioma and cytotoxicity of sirolimus in vitro. | 2021 Jul |
1 |
| 10 |
34421360 | Rapamycin and trametinib: a rational combination for treatment of NSCLC. | 2021 |
1 |
| 11 |
34738031 | Regulation of mTORC1 by amino acids in mammalian cells: A general picture of recent advances. | 2021 Dec |
2 |
| 12 |
31896113 | Immunohistochemical Analysis of mTOR Pathway-Related Proteins in Kaposiform Hemangioendothelioma. | 2020 |
1 |
| 13 |
32108266 | Leucine and mTORc1 act independently to regulate 2-deoxyglucose uptake in L6 myotubes. | 2020 Mar |
1 |
| 14 |
32753891 | Downregulation of RRM2 Attenuates Retroperitoneal Liposarcoma Progression via the Akt/mTOR/4EBP1 Pathway: Clinical, Biological, and Therapeutic Significance. | 2020 |
1 |
| 15 |
30552925 | Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin. | 2019 Mar 15 |
5 |
| 16 |
30602778 | The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. | 2019 Jan 2 |
1 |
| 17 |
31487224 | Endurance exercise decreases protein synthesis and ER-mitochondria contacts in mouse skeletal muscle. | 2019 Nov 1 |
1 |
| 18 |
31878201 | Inhibition of Growth of TSC2-Null Cells by a PI3K/mTOR Inhibitor but Not by a Selective MNK1/2 Inhibitor. | 2019 Dec 24 |
1 |
| 19 |
28300280 | Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells. | 2018 Jan |
1 |
| 20 |
28696243 | Inhibiting 4EBP1 in Glioblastoma. | 2018 Jan 1 |
1 |
| 21 |
28969943 | Deciphering the pathways that protect from IL-13-mediated potentiation of oxidative stress-induced dopaminergic nerve cell death. | 2018 Mar |
1 |
| 22 |
30050079 | Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells. | 2018 Jul 26 |
1 |
| 23 |
27832967 | Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002. | 2017 Jan 15 |
2 |
| 24 |
27245614 | The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes. | 2016 May 31 |
1 |
| 25 |
27297394 | Microfilariae of Brugia malayi Inhibit the mTOR Pathway and Induce Autophagy in Human Dendritic Cells. | 2016 Sep |
1 |
| 26 |
25200808 | Intravesical bacillus Calmette-Guérin efficiently reduces p70S6K1 but not 4E-BP1 phosphorylation in nonmuscle invasive bladder cancer. | 2015 Feb |
1 |
| 27 |
25439783 | The 4E-BP1/eIF4E ratio is a determinant for rapamycin response in esophageal cancer cells. | 2015 Jan |
6 |
| 28 |
25657110 | Fibronectin promotes cell proliferation and invasion through mTOR signaling pathway activation in gallbladder cancer. | 2015 May 1 |
1 |
| 29 |
25659819 | Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways. | 2015 May 1 |
3 |
| 30 |
25744729 | Validation of p27KIP1 expression levels as a candidate predictive biomarker of response to rapalogs in patient-derived breast tumor xenografts. | 2015 Mar |
1 |
| 31 |
25762619 | Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion. | 2015 Mar 30 |
3 |
| 32 |
25880415 | FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth. | 2015 Mar 28 |
1 |
| 33 |
25961827 | AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis. | 2015 Jun 10 |
3 |
| 34 |
25988388 | Suppression of the proliferation of hypoxia-Induced retinal pigment epithelial cell by rapamycin through the /mTOR/HIF-1α/VEGF/ signaling. | 2015 Jun |
1 |
| 35 |
26002629 | Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways. | 2015 Oct |
1 |
| 36 |
26189041 | Targeting mTOR/p70S6K/glycolysis signaling pathway restores glucocorticoid sensitivity to 4E-BP1 null Burkitt Lymphoma. | 2015 Jul 20 |
2 |
| 37 |
26540919 | [Activation of mTOR signaling pathway in cancer stem cells of nasopharyngeal carcinoma and inhibitive effect of rapamycin against the cancer stem cells]. | 2015 Jul |
2 |
| 38 |
23708663 | Accumulation of dephosphorylated 4EBP after mTOR inhibition with rapamycin is sufficient to disrupt paracrine transformation by the KSHV vGPCR oncogene. | 2014 May 1 |
1 |
| 39 |
24675464 | Rapamycin delays salivary gland atrophy following ductal ligation. | 2014 Mar 27 |
1 |
| 40 |
24682932 | Rapamycin combined with celecoxib enhanced antitumor effects of mono treatment on chronic myelogenous leukemia cells through downregulating mTOR pathway. | 2014 Jul |
2 |
| 41 |
23261705 | Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway. | 2013 Feb 5 |
1 |
| 42 |
23273915 | S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1. | 2013 Jan 31 |
1 |
| 43 |
23376634 | Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest. | 2013 Jun 10 |
2 |
| 44 |
23482748 | Comparative effects of PP242 and rapamycin on mTOR signalling and NOTCH signalling in leukemia cells. | 2013 Mar |
1 |
| 45 |
21922152 | Association between LRRK2 and 4E-BP1 protein levels in normal and malignant cells. | 2012 Jan |
1 |
| 46 |
21993902 | Rapamycin provides a therapeutic option through inhibition of mTOR signaling in chronic myelogenous leukemia. | 2012 Feb |
1 |
| 47 |
22184107 | Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation. | 2012 Feb 10 |
1 |
| 48 |
22496482 | Predominance of mTORC1 over mTORC2 in the regulation of proliferation of ovarian cancer cells: therapeutic implications. | 2012 Jun |
1 |
| 49 |
22767218 | Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype. | 2012 Sep |
1 |
| 50 |
23384908 | [Inhibitory effects of rapamycin on proliferation of chronic myelogenous leukemia cells and its mechanism]. | 2012 Oct |
1 |