Leucine

eukaryotic translation initiation factor 4E binding protein 1 ; Homo sapiens







23 Article(s)
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1 30265371 Effects of in ovo feeding of L-leucine on amino acids metabolism and heat-shock protein-70, and -90 mRNA expression in heat-exposed chicks. 2019 Mar 1 1
2 30761631 Leucine-induced promotion of post-absorptive EAA utilization and hepatic gluconeogenesis contributes to protein synthesis in skeletal muscle of dairy calves. 2019 May 1
3 29795412 Effects of single amino acid deficiency on mRNA translation are markedly different for methionine versus leucine. 2018 May 24 3
4 25553480 Nutritional and regulatory roles of leucine in muscle growth and fat reduction. 2015 Jan 1 2
5 23783244 Acute uremia suppresses leucine-induced signal transduction in skeletal muscle. 2014 Feb 1
6 22391631 Enteral leucine supplementation increases protein synthesis in skeletal and cardiac muscles and visceral tissues of neonatal pigs through mTORC1-dependent pathways. 2012 Apr 2
7 22442136 Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine. 2012 May 15 1
8 21293034 Select nutrients in the ovine uterine lumen. IX. Differential effects of arginine, leucine, glutamine, and glucose on interferon tau, ornithine decarboxylase, and nitric oxide synthase in the ovine conceptus. 2011 Jun 1
9 21906315 Upstream molecular signaling pathways of p27(Kip1) expression in human breast cancer cells in vitro: differential effects of 4-hydroxytamoxifen and deficiency of either D-(+)-glucose or L-leucine. 2011 Sep 9 1
10 20473536 Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs. 2010 Nov 1
11 17505052 Regulation of muscle protein synthesis during sepsis and inflammation. 2007 Aug 1
12 17707924 Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells. 2007 Nov 1
13 16365087 Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis. 2006 Jan 1
14 16897753 Leucine stimulates procollagen alpha1(I) translation on hepatic stellate cells through ERK and PI3K/Akt/mTOR activation. 2006 Nov 1
15 15228219 Tissue-specific regulation of 4E-BP1 and S6K1 phosphorylation by alpha-ketoisocaproate. 2004 Feb 2
16 12611592 Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability. 2003 Jun 1 1
17 11790952 Control of protein synthesis by amino acid availability. 2002 Jan 1
18 11238774 Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine. 2001 Mar 2
19 10723090 Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes. 2000 Mar 3
20 10206976 Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6. 1999 Apr 23 2
21 9774438 Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling. 1998 Oct 23 2
22 9812990 Implication of eIF2B rather than eIF4E in the regulation of global protein synthesis by amino acids in L6 myoblasts. 1998 Nov 20 2
23 9814971 Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes. 1998 Nov 3