| 1 |
35219878 | NAMPT: A critical driver and therapeutic target for cancer. | 2022 Apr |
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| 2 |
35251333 | Sirtuin 1 participates in intervertebral disc degeneration via the nicotinamide phosphoribosyl transferase/nicotinamide adenine dinucleotide/sirtuin 1 pathway responsible for regulating autophagy of nucleus pulposus cells. | 2022 Apr |
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| 3 |
35408818 | NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy. | 2022 Mar 22 |
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| 4 |
33446046 | Accelerated cardiovascular risk after viral clearance in hepatitis C patients with the NAMPT-rs61330082 TT genotype: An 8-year prospective cohort study. | 2021 Dec |
1 |
| 5 |
34201564 | eNAMPT Is Localised to Areas of Cartilage Damage in Patients with Hip Osteoarthritis and Promotes Cartilage Catabolism and Inflammation. | 2021 Jun 23 |
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| 6 |
34229568 | Structure-based virtual screening, molecular dynamics simulation and in vitro evaluation to identify inhibitors against NAMPT. | 2021 Jul 6 |
2 |
| 7 |
34430962 | The Role of Visfatin (Adipocytokine) Biomarker in Oral Health and Diseases among Nonobese Indian Population: A Proteomic Assay. | 2021 Sep |
1 |
| 8 |
31818629 | Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. | 2020 Jan 1 |
2 |
| 9 |
31898286 | α-Mangostin reduced the viability of A594 cells in vitro by provoking ROS production through downregulation of NAMPT/NAD. | 2020 Jan |
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| 10 |
31919382 | The effect of NAMPT deletion in projection neurons on the function and structure of neuromuscular junction (NMJ) in mice. | 2020 Jan 9 |
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| 11 |
31988240 | A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus. | 2020 Mar 13 |
2 |
| 12 |
32005247 | Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level. | 2020 Jan 31 |
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| 13 |
32252104 | Serum Visfatin does not seem to be a Useful Marker to Guide Glucocorticoid Substitution in Adrenal Insufficiency. | 2020 May |
1 |
| 14 |
32266141 | NAMPT and NAPRT: Two Metabolic Enzymes With Key Roles in Inflammation. | 2020 |
1 |
| 15 |
32428995 | Impaired nicotinamide adenine dinucleotide (NAD+ ) metabolism in diabetes and diabetic tissues: Implications for nicotinamide-related compound treatment. | 2020 Nov |
2 |
| 16 |
32822582 | Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells. | 2020 Nov 5 |
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| 17 |
32878777 | Effect of Phosphoribosyltransferase Down-regulation on Malignant Glioma Cell Characteristics. | 2020 Sep |
2 |
| 18 |
30514106 | SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells. | 2019 Mar |
1 |
| 19 |
30875389 | Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry. | 2019 |
2 |
| 20 |
31338216 | Targeting NAMPT as a therapeutic strategy against stroke. | 2019 Jul |
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| 21 |
31614144 | High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor. | 2019 Dec 15 |
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| 22 |
31803365 | Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent. | 2019 Nov 19 |
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| 23 |
31888244 | Mutant IDH1 Differently Affects Redox State and Metabolism in Glial Cells of Normal and Tumor Origin. | 2019 Dec 16 |
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| 24 |
29207896 | Rho GTPase effectors and NAD metabolism in cancer immune suppression. | 2018 Jan |
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| 25 |
29478906 | Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites. | 2018 Apr 19 |
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| 26 |
29541451 | Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA. | 2018 |
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| 27 |
29653431 | Inhibition of NAMPT sensitizes MOLT4 leukemia cells for etoposide treatment through the SIRT2-p53 pathway. | 2018 Jun |
2 |
| 28 |
28035412 | Nicotinamide phosphoribosyltransferase inhibits receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation in vitro. | 2017 Feb |
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| 29 |
28468779 | Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors. | 2017 Jul |
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| 30 |
28756225 | Identification of novel resistance mechanisms to NAMPT inhibition via the de novo NAD+ biosynthesis pathway and NAMPT mutation. | 2017 Sep 23 |
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| 31 |
28819322 | NAMPT enzyme activity regulates catabolic gene expression in gingival fibroblasts during periodontitis. | 2017 Aug 18 |
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| 32 |
29156703 | Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer. | 2017 Oct 17 |
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| 33 |
27018006 | Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis. | 2016 Jun |
3 |
| 34 |
27608947 | NAMPT inhibition synergizes with NQO1-targeting agents in inducing apoptotic cell death in non-small cell lung cancer cells. | 2016 Aug |
2 |
| 35 |
27711204 | Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable. | 2016 |
2 |
| 36 |
25656579 | FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells. | 2015 Mar 6 |
2 |
| 37 |
25894564 | Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid. | 2015 Mar |
2 |
| 38 |
26024774 | Apoptosis induced by NAD depletion is inhibited by KN-93 in a CaMKII-independent manner. | 2015 Jul 1 |
1 |
| 39 |
26330291 | A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling. | 2015 Dec |
1 |
| 40 |
26542945 | EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. | 2015 Nov 5 |
2 |
| 41 |
24389478 | Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening. | 2014 |
2 |
| 42 |
23435312 | NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity. | 2013 Jun |
5 |
| 43 |
23880765 | CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. | 2013 Sep 6 |
1 |
| 44 |
24403854 | Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models. | 2013 Dec |
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| 45 |
22044451 | Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models. | 2012 Jan |
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| 46 |
22430142 | NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression. | 2012 Apr 20 |
2 |
| 47 |
20956937 | NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response. | 2011 Feb 24 |
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| 48 |
21517777 | NAMPT in regulated NAD biosynthesis and its pivotal role in human metabolism. | 2011 |
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| 49 |
21826208 | Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma. | 2011 |
1 |
| 50 |
21884623 | Virtual screening, identification and experimental testing of novel inhibitors of PBEF1/Visfatin/NMPRTase for glioma therapy. | 2011 Jan 20 |
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