Niacin

nicotinamide phosphoribosyltransferase ; Homo sapiens







11 Article(s)
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Title
Pub. Year
#Total Relationships
1 35396381 Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia. 2022 Apr 8 1
2 32266141 NAMPT and NAPRT: Two Metabolic Enzymes With Key Roles in Inflammation. 2020 1
3 29949049 Targeting glucose transport and the NAD pathway in tumor cells with STF-31: a re-evaluation. 2018 Oct 1
4 27783203 Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines. 2017 Jul 1
5 29054982 Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration. 2017 Dec 1
6 26675378 Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors. 2016 Jan 12 1
7 25894564 Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid. 2015 Mar 2
8 25201160 NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples. 2014 Sep 9 1
9 24097869 Loss of NAPRT1 expression by tumor-specific promoter methylation provides a novel predictive biomarker for NAMPT inhibitors. 2013 Dec 15 1
10 24204194 Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618. 2013 Oct 1
11 24403854 Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models. 2013 Dec 1