fostamatinib

spleen tyrosine kinase ; Mus musculus







7 Article(s)
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1 35551173 Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration. 2022 May 13 2
2 33294858 A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury. 2020 Nov 17 2
3 26148346 Spleen tyrosine kinase (Syk) inhibitor fostamatinib limits tissue damage and fibrosis in a bleomycin-induced scleroderma mouse model. 2015 Jul-Aug 6
4 22301676 Spleen tyrosine kinase (Syk) is a potent target for GvHD prevention at different cellular levels. 2012 Jul 1
5 22492694 Inhibition of Syk activity by R788 in platelets prevents remote lung tissue damage after mesenteric ischemia-reperfusion injury. 2012 Jun 15 1
6 21700926 The oral spleen tyrosine kinase inhibitor fostamatinib attenuates inflammation and atherogenesis in low-density lipoprotein receptor-deficient mice. 2011 Sep 3
7 20716772 The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling. 2010 Dec 2 1