Phosphatidylinositol 4,5-Diphosphate

potassium inwardly rectifying channel subfamily J member 11 ; Homo sapiens







21 Article(s)
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1 34447786 Simulating PIP2-Induced Gating Transitions in Kir6.2 Channels. 2021 2
2 28086082 Structure of a Pancreatic ATP-Sensitive Potassium Channel. 2017 Jan 12 2
3 28092267 Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating. 2017 Jan 16 3
4 25934393 A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels. 2015 Jun 19 1
5 24429282 Phosphatidylinositol 4,5-biphosphate (PIP2) modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic β-cell ATP-sensitive potassium channels. 2014 Feb 28 2
6 23700433 A Kir6.2 pore mutation causes inactivation of ATP-sensitive potassium channels by disrupting PIP2-dependent gating. 2013 1
7 22851715 Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6.2/SUR2A channels. 2012 Nov 1
8 21321069 N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2. 2011 Mar 2
9 21654216 ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity. 2011 Jul-Aug 1
10 21779761 Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels. 2011 Oct 1
11 20208975 Voltage-dependent gating in a "voltage sensor-less" ion channel. 2010 Feb 23 1
12 17673911 Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis. 2007 Aug 22 1
13 16373383 ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2. 2006 Mar 1 2
14 15980413 Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels. 2005 Sep 2 1
15 16246010 Molecular simulations and lipid-protein interactions: potassium channels and other membrane proteins. 2005 Nov 1
16 12475570 Regulation of cardiac inwardly rectifying potassium channels by membrane lipid metabolism. 2003 Jan 1
17 14561820 Long-chain acyl-CoA esters and phosphatidylinositol phosphates modulate ATP inhibition of KATP channels by the same mechanism. 2003 Oct 15 2
18 11585851 Regulation of cloned ATP-sensitive K channels by adenine nucleotides and sulfonylureas: interactions between SUR1 and positively charged domains on Kir6.2. 2001 Oct 1
19 10969822 Phosphatidylinositol 4,5-bisphosphate and ATP-sensitive potassium channel regulation: a word of caution. 2000 Sep 2
20 10435998 Sulfonylurea and K(+)-channel opener sensitivity of K(ATP) channels. Functional coupling of Kir6.2 and SUR1 subunits. 1999 Aug 1
21 9804555 PIP2 and PIP as determinants for ATP inhibition of KATP channels. 1998 Nov 6 2