| 1 |
33646450 | PPAR-δ activation reduces cisplatin-induced apoptosis via inhibiting p53/Bax/caspase-3 pathway without modulating autophagy in murine renal proximal tubular cells. | 2021 Jun |
2 |
| 2 |
30453390 | PPARβ/δ-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes. | 2019 Jan |
3 |
| 3 |
31008686 | PPAR-δ Activation Ameliorates Diabetes-Induced Cognitive Dysfunction by Modulating Integrin-linked Kinase and AMPA Receptor Function. | 2019 Nov-Dec |
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| 4 |
31635041 | Complementary Immunometabolic Effects of Exercise and PPARβ/δ Agonist in the Context of Diet-Induced Weight Loss in Obese Female Mice. | 2019 Oct 19 |
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| 5 |
29580823 | GW0742 (PPAR-beta agonist) attenuates hepatic endoplasmic reticulum stress by improving hepatic energy metabolism in high-fat diet fed mice. | 2018 Oct 15 |
2 |
| 6 |
29697010 | Delayed activation of PPAR-β/δ improves long-term survival in mouse sepsis: effects on organ inflammation and coagulation. | 2018 May |
1 |
| 7 |
30227151 | The PPARδ agonist GW0742 restores neuroimmune function by regulating Tim-3 and Th17/Treg-related signaling in the BTBR autistic mouse model. | 2018 Nov |
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| 8 |
27818230 | Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury. | 2017 Apr |
2 |
| 9 |
27939528 | Peroxisome Proliferator Activated Receptor Beta (PPARβ) activity increases the immune response and shortens the early phases of skeletal muscle regeneration. | 2017 May |
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| 10 |
28242713 | Activation of Peroxisome Proliferator Activator Receptor β/δ Improves Endothelial Dysfunction and Protects Kidney in Murine Lupus. | 2017 Apr |
2 |
| 11 |
26655383 | α-Lipoic acid up-regulates expression of peroxisome proliferator-activated receptor β in skeletal muscle: involvement of the JNK signaling pathway. | 2016 Mar |
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| 12 |
26864581 | PPARδ agonist GW0742 ameliorates Aβ1-42-induced hippocampal neurotoxicity in mice. | 2016 Jun |
2 |
| 13 |
26997622 | Combined pharmacological activation of AMPK and PPARδ potentiates the effects of exercise in trained mice. | 2016 Mar |
1 |
| 14 |
27150147 | Pulmonary Administration of GW0742, a High-Affinity Peroxisome Proliferator-Activated Receptor Agonist, Repairs Collapsed Alveoli in an Elastase-Induced Mouse Model of Emphysema. | 2016 |
1 |
| 15 |
27179975 | Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction. | 2016 Jun 15 |
2 |
| 16 |
27189971 | Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5. | 2016 Jul |
1 |
| 17 |
25592770 | Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer's disease through inhibition of inflammation. | 2015 Jan 16 |
2 |
| 18 |
25662586 | PPAR-β/δ activation promotes phospholipid transfer protein expression. | 2015 Mar 15 |
3 |
| 19 |
26253087 | Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction. | 2015 Nov |
1 |
| 20 |
26508837 | Development of PPAR-agonist GW0742 as antidiabetic drug: study in animals. | 2015 |
1 |
| 21 |
24814977 | Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice. | 2014 Jul |
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| 22 |
23103566 | Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR-δ agonism correlates with impaired NLRP3 inflammasome activation. | 2013 Jan 15 |
2 |
| 23 |
23499837 | The PPARδ agonist GW0742 inhibits neuroinflammation, but does not restore neurogenesis or prevent early delayed hippocampal-dependent cognitive impairment after whole-brain irradiation. | 2013 Aug |
2 |
| 24 |
23500098 | A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. | 2013 Jun 14 |
1 |
| 25 |
23861559 | High sugar intake and development of skeletal muscle insulin resistance and inflammation in mice: a protective role for PPAR- δ agonism. | 2013 |
2 |
| 26 |
25006409 | The peroxisome proliferator-activated receptor β/δ agonist GW0742 has direct protective effects on right heart hypertrophy. | 2013 Dec |
2 |
| 27 |
21685825 | GW0742, a high-affinity PPAR-δ agonist, mediates protection in an organotypic model of spinal cord damage. | 2012 Jan 15 |
3 |
| 28 |
22521259 | Peroxisome proliferator-activated receptor β/δ agonist GW0742 ameliorates cerulein- and taurocholate-induced acute pancreatitis in mice. | 2012 Jul |
1 |
| 29 |
21426320 | Generation and characterization of a humanized PPARδ mouse model. | 2011 Sep |
1 |
| 30 |
21765606 | Administration of PPARβ/δ agonist reduces copper-induced liver damage in mice: possible implications in clinical practice. | 2011 Jul |
1 |
| 31 |
21798999 | PPARbeta activation induces rapid changes of both AMPK subunit expression and AMPK activation in mouse skeletal muscle. | 2011 Sep |
1 |
| 32 |
19748995 | Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis. | 2010 Jan |
1 |
| 33 |
20001953 | Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins. | 2010 Jan 15 |
1 |
| 34 |
20167109 | Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study. | 2010 Feb 18 |
1 |
| 35 |
20176685 | Evidence for the role of peroxisome proliferator-activated receptor-beta/delta in the development of spinal cord injury. | 2010 May |
1 |
| 36 |
20407409 | GW0742, a high-affinity PPAR -beta/delta agonist, inhibits acute lung injury in mice. | 2010 Apr |
3 |
| 37 |
20430778 | GW0742, a selective PPAR-beta/delta agonist, contributes to the resolution of inflammation after gut ischemia/reperfusion injury. | 2010 Aug |
2 |
| 38 |
20693380 | Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock. | 2010 Dec 15 |
1 |
| 39 |
20709805 | Peroxisome proliferator-activated receptor {delta} regulates inflammation via NF-{kappa}B signaling in polymicrobial sepsis. | 2010 Oct |
2 |
| 40 |
21159610 | Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2. | 2010 Dec |
2 |
| 41 |
21244753 | GW0742, a high affinity PPAR-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice. | 2010 Oct-Dec |
2 |
| 42 |
19577614 | Mouse carnitine-acylcarnitine translocase (CACT) is transcriptionally regulated by PPARalpha and PPARdelta in liver cells. | 2009 Oct |
1 |
| 43 |
20169010 | Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol. | 2009 Apr |
1 |
| 44 |
17893232 | Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms. | 2008 Jan |
1 |
| 45 |
18593727 | PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742. | 2008 Oct |
1 |
| 46 |
18622026 | Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression. | 2008 Oct |
1 |
| 47 |
18622687 | Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742. | 2008 Jul |
4 |
| 48 |
18627005 | Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice. | 2008 Aug |
1 |
| 49 |
17631136 | Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice. | 2007 Jul |
1 |
| 50 |
16021179 | PPARbeta/delta selectively induces differentiation and inhibits cell proliferation. | 2006 Jan |
1 |