| 1 |
26923072 | The protein inhibitor of nNOS (PIN/DLC1/LC8) binding does not inhibit the NADPH-dependent heme reduction in nNOS, a key step in NO synthesis. | 2016 Mar 25 |
2 |
| 2 |
25921643 | Computational development of selective nNOS inhibitors: binding modes and pharmacokinetic considerations. | 2015 |
2 |
| 3 |
24610812 | Energy landscapes and catalysis in nitric-oxide synthase. | 2014 Apr 25 |
2 |
| 4 |
24737326 | Architecture of the nitric-oxide synthase holoenzyme reveals large conformational changes and a calmodulin-driven release of the FMN domain. | 2014 Jun 13 |
1 |
| 5 |
23572278 | Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. | 2013 Apr |
2 |
| 6 |
24129225 | Alterations in the expression of nNOS in the substantia nigra and subthalamic nucleus of 6-OHDA-lesioned rats: the effects of chronic treatment with l-DOPA and the nitric oxide donor, molsidomine. | 2013 Dec 6 |
1 |
| 7 |
22929836 | Detection of nitric oxide and superoxide radical anion by electron paramagnetic resonance spectroscopy from cells using spin traps. | 2012 Aug 18 |
1 |
| 8 |
20950274 | Mesohaem substitution reveals how haem electronic properties can influence the kinetic and catalytic parameters of neuronal NO synthase. | 2011 Jan 1 |
1 |
| 9 |
24453460 | DINITROBENZENES STIMULATE ELECTRON FLUX WITHIN NEURONAL NITRIC OXIDE SYNTHASE IN THE ABSENCE OF CALMODULIN. | 2011 |
8 |
| 10 |
20529840 | A bridging interaction allows calmodulin to activate NO synthase through a bi-modal mechanism. | 2010 Aug 20 |
1 |
| 11 |
18052254 | Oxygen-induced radical intermediates in the nNOS oxygenase domain regulated by L-arginine, tetrahydrobiopterin, and thiol. | 2008 Jan 8 |
2 |
| 12 |
18370414 | Metabolic activation of the antitumor drug 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB1954) by NO synthases. | 2008 Apr |
2 |
| 13 |
17454123 | The endogenous neurotransmitter, serotonin, modifies neuronal nitric oxide synthase activities. | 2007 Apr |
1 |
| 14 |
16085316 | In situ measurement of neuronal nitric oxide synthase activity in the spinal cord by NADPH-diaphorase histochemistry. | 2006 Jan 30 |
2 |
| 15 |
16966328 | The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases. | 2006 Nov 10 |
2 |
| 16 |
17236649 | Phylogenesis of constitutively formed nitric oxide in non-mammals. | 2006 |
2 |
| 17 |
15748708 | L-arginine regulates neuronal nitric oxide synthase production of superoxide and hydrogen peroxide. | 2005 Mar 15 |
1 |
| 18 |
16150731 | C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase. | 2005 Nov 25 |
1 |
| 19 |
14681230 | Identification of caveolin-1-interacting sites in neuronal nitric-oxide synthase. Molecular mechanism for inhibition of NO formation. | 2004 Mar 5 |
1 |
| 20 |
14769337 | Application of the measurement of oxidized pyridine dinucleotides with high-performance liquid chromatography-fluorescence detection to assay the uncoupled oxidation of NADPH by neuronal nitric oxide synthase. | 2004 Mar 1 |
7 |
| 21 |
14966111 | A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis. | 2004 Apr 30 |
1 |
| 22 |
15180983 | The FAD-shielding residue Phe1395 regulates neuronal nitric-oxide synthase catalysis by controlling NADP+ affinity and a conformational equilibrium within the flavoprotein domain. | 2004 Aug 20 |
3 |
| 23 |
15323562 | Redox properties of the isolated flavin mononucleotide- and flavin adenine dinucleotide-binding domains of neuronal nitric oxide synthase. | 2004 Aug 31 |
1 |
| 24 |
12646269 | Electron transfer is activated by calmodulin in the flavin domain of human neuronal nitric oxide synthase. | 2003 Apr 1 |
4 |
| 25 |
12777376 | Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human neuronal nitric-oxide synthase and inducible nitric-oxide synthase flavin domains. | 2003 Aug 15 |
1 |
| 26 |
11772017 | Neuronal nitric oxide synthase: substrate and solvent kinetic isotope effects on the steady-state kinetic parameters for the reduction of 2,6-dichloroindophenol and cytochrome c(3+). | 2002 Jan 8 |
1 |
| 27 |
12089147 | Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock. | 2002 Sep 13 |
1 |
| 28 |
11038356 | A kinetic simulation model that describes catalysis and regulation in nitric-oxide synthase. | 2001 Jan 12 |
1 |
| 29 |
11125020 | Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme. | 2001 Jan |
1 |
| 30 |
11150917 | Effect of isosorbide dinitrate on nitric oxide synthase under hypoxia. | 2001 Jan |
1 |
| 31 |
10681501 | Interaction of endothelial and neuronal nitric-oxide synthases with the bradykinin B2 receptor. Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation. | 2000 Feb 25 |
1 |
| 32 |
10799481 | Cu2+ and Zn2+ inhibit nitric-oxide synthase through an interaction with the reductase domain. | 2000 May 12 |
4 |
| 33 |
10924903 | One-electron reduction of quinones by the neuronal nitric-oxide synthase reductase domain. | 2000 Jul 20 |
2 |
| 34 |
10945985 | Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism. | 2000 Oct 27 |
1 |
| 35 |
10417510 | Expression of the neuronal isoform of nitric oxide synthase (nNOS) and its inhibitor, protein inhibitor of nNOS, in pigment cell lesions of the skin. | 1999 Jul |
2 |
| 36 |
10428800 | Role of reductase domain cluster 1 acidic residues in neuronal nitric-oxide synthase. Characterization of the FMN-FREE enzyme. | 1999 Aug 6 |
1 |
| 37 |
10503941 | Neuronal nitric oxide synthase catalyzes the reduction of 7-ethoxyresorufin. | 1999 |
3 |
| 38 |
10521442 | The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca(2+)/calmodulin-dependent electron transfer. | 1999 Oct 22 |
1 |
| 39 |
10594372 | Calmodulin activates intramolecular electron transfer between the two flavins of neuronal nitric oxide synthase flavin domain. | 1999 Dec 27 |
1 |
| 40 |
9535869 | N5-(1-Imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase. | 1998 Apr 10 |
3 |
| 41 |
9688579 | The protein inhibitor of neuronal nitric oxide synthase (PIN): characterization of its action on pure nitric oxide synthases. | 1998 Jul 3 |
1 |
| 42 |
9312270 | Analysis of neuronal NO synthase under single-turnover conditions: conversion of Nomega-hydroxyarginine to nitric oxide and citrulline. | 1997 Sep 9 |
3 |
| 43 |
9398256 | Involvement of the reductase domain of neuronal nitric oxide synthase in superoxide anion production. | 1997 Dec 9 |
1 |
| 44 |
8927232 | Haloperidol inhibits neuronal nitric oxide synthase activity by preventing electron transfer. | 1996 |
1 |
| 45 |
8955074 | Nitric oxide binding to the heme of neuronal nitric-oxide synthase links its activity to changes in oxygen tension. | 1996 Dec 20 |
1 |
| 46 |
7578122 | Inhibition of nitric oxide synthase activity by Zn2+ ion. | 1995 Nov 21 |
1 |