| 1 |
31998607 | The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids. | 2020 Jan |
1 |
| 2 |
32492461 | Pyrazinamide alleviates rifampin-induced steatohepatitis in mice by regulating the activities of cholesterol-activated 7α-hydroxylase and lipoprotein lipase. | 2020 Aug 1 |
5 |
| 3 |
31455676 | CYP3A4 Induction in the Liver and Intestine of Pregnane X Receptor/CYP3A-Humanized Mice: Approaches by Mass Spectrometry Imaging and Portal Blood Analysis. | 2019 Nov |
1 |
| 4 |
29095659 | Indirect activation of pregnane X receptor in the induction of hepatic CYP3A11 by high-dose rifampicin in mice. | 2018 Nov |
4 |
| 5 |
29358328 | A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin. | 2018 Mar 9 |
4 |
| 6 |
28345929 | Utility of CYP3A4 and PXR-CAR-CYP3A4/3A7 Transgenic Mouse Models To Assess the Magnitude of CYP3A4 Mediated Drug-Drug Interactions. | 2017 May 1 |
1 |
| 7 |
27806127 | Rifampicin-Induced Hepatic Lipid Accumulation: Association with Up-Regulation of Peroxisome Proliferator-Activated Receptor γ in Mouse Liver. | 2016 |
1 |
| 8 |
25749104 | Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage. | 2015 |
3 |
| 9 |
25835148 | Expression of hepatic cytochrome P450s and UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with rifampicin. | 2015 Jun 1 |
1 |
| 10 |
25341566 | Resveratrol suppresses the inducible expression of CYP3A4 through the pregnane X receptor. | 2014 |
1 |
| 11 |
22253426 | Expression and regulation of human fetal-specific CYP3A7 in mice. | 2012 Mar |
1 |
| 12 |
22687401 | Establishment of a stable human cell line, HPL-A3, for use in reporter gene assays of cytochrome P450 3A inducers. | 2012 |
1 |
| 13 |
21205914 | Pharmacokinetic-pharmacodynamic modeling of rifampicin-mediated Cyp3a11 induction in steroid and xenobiotic X receptor humanized mice. | 2011 Apr |
3 |
| 14 |
20054495 | Rifampicin Inhibits the LPS-induced Expression of Toll-like Receptor 2 via the Suppression of NF-kappaB DNA-binding Activity in RAW 264.7 Cells. | 2009 Dec |
4 |
| 15 |
17962516 | Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance. | 2008 Feb |
2 |
| 16 |
18765524 | Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer. | 2008 Sep 1 |
1 |
| 17 |
18799805 | A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4. | 2008 Dec |
1 |
| 18 |
16973756 | Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis. | 2007 Jan |
1 |
| 19 |
17093002 | The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. | 2007 Feb |
3 |
| 20 |
17936928 | CYP3A4 and pregnane X receptor humanized mice. | 2007 |
1 |
| 21 |
15183191 | Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver. | 2004 Jul 1 |
1 |
| 22 |
12781341 | In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors. | 2003 Jun 1 |
2 |
| 23 |
12920130 | Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. | 2003 Nov 7 |
1 |
| 24 |
10628745 | The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. | 2000 Jan |
1 |
| 25 |
10772631 | Rabbit pregnane X receptor is activated by rifampicin. | 2000 May |
1 |