Phenobarbital

nuclear receptor subfamily 1, group I, member 2 ; Mus musculus







16 Article(s)
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Title
Pub. Year
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1 32735318 Comparison of the Hepatic Effects of Phenobarbital in Chimeric Mice Containing Either Rat or Human Hepatocytes With Humanized Constitutive Androstane Receptor and Pregnane X Receptor Mice. 2020 Oct 1 2
2 31436536 Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor. 2019 Sep 2
3 28058446 Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice. 2017 Aug 1
4 28218408 Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor. 2017 Aug 2
5 27664318 Methyl isobutyl ketone-induced hepatocellular carcinogenesis in B6C3F1 mice: A constitutive androstane receptor (CAR)-mediated mode of action. 2016 Nov 1
6 26215100 Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR). 2015 Oct 2 2
7 24690595 Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors. 2014 Jun 7
8 24863967 Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR. 2014 Aug 1 5
9 20371638 The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver. 2010 Jul 4
10 20403969 Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo. 2010 Aug 1
11 19708687 Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR. 2009 Sep-Oct 5
12 18677425 A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. 2008 Sep 1
13 17020958 Gender dictates the nuclear receptor-mediated regulation of CYP3A44. 2007 Jan 1
14 16799975 Phenobarbital regulates nuclear expression of HNF-4alpha in mouse and rat hepatocytes independent of CAR and PXR. 2006 Jul 4
15 12695338 Regulation of drug transporter gene expression by nuclear receptors. 2003 May 6
16 11114890 Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. 2000 Dec 1 1