Simvastatin

interleukin 6 ; Homo sapiens







80 Article(s)
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51 19205663 The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: a randomized double-blind placebo controlled clinical trial. 2009 Jul 1
52 19640331 Effect of simvastatin on plasma interleukin-6 in patients with unstable angina. 2009 Aug 1 3
53 20065508 IL-6 and IL-8 responses of colorectal cancer in vivo and in vitro cancer cells subjected to simvastatin. 2009 Dec 6
54 18203325 High concentration simvastatin induces apoptosis in fibroblast-like synoviocytes from patients with rheumatoid arthritis. 2008 Feb 3
55 18264935 Effect of simvastatin on plasma asymmetric dimethylarginine concentration in patients with chronic kidney disease. 2008 Jan-Feb 1
56 18698233 Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression. 2008 Sep 1
57 16942919 Simvastatin stimulates macrophage interleukin-1beta secretion through an isoprenylation-dependent mechanism. 2007 Feb 1
58 17261959 Impact of simvastatin and losartan on antiinflammatory effect: in vitro study. 2007 Jan 2
59 17383342 Simvastatin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery. 2007 Apr 1
60 17466485 Simvastatin and fluvastatin reduce interleukin-6 and interleukin-8 lipopolysaccharide (LPS) stimulated production by isolated human monocytes from chronic kidney disease patients. 2007 Jul 2
61 17888208 Influence of simvastatin on the production of pro-inflammatory cytokines and nitric oxide by activated human chondrocytes. 2007 Jul-Aug 3
62 18078616 Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. 2007 Sep-Oct 3
63 18260853 [Clinico-diagnostic significance of cytokine activation and changes of morphofunctional parameters of the heart in patients with chronic heart failure and possibilities of correction of revealed disturbances with simvastatin]. 2007 1
64 16054696 Statins and nitric oxide reduce C-reactive protein production while inflammatory conditions persist. 2006 Mar 2
65 16249194 In vivo and in vitro effects of simvastatin on inflammatory markers in pre-dialysis patients. 2006 Feb 1
66 16511915 Simvastatin inhibits production of interleukin 6 (IL-6) and IL-8 and cell proliferation induced by tumor necrosis factor-alpha in fibroblast-like synoviocytes from patients with rheumatoid arthritis. 2006 Mar 8
67 16518530 Early effects of simvastatin versus atorvastatin on oxidative stress and proinflammatory cytokines in hyperlipidemic subjects. 2006 Mar-Apr 1
68 16723648 Simvastatin decreases IL-6 and IL-8 production in epithelial cells. 2006 Jun 2
69 16968805 Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome. 2006 Nov 1
70 17075836 RhoA-mediated, tumor necrosis factor alpha-induced activation of NF-kappaB in rheumatoid synoviocytes: inhibitory effect of simvastatin. 2006 Nov 1
71 16118799 Effects of statins on microglia. 2005 Oct 1 2
72 16275545 The dependence of serum interleukin-6 level on PPAR-alpha polymorphism in men with coronary atherosclerosis. 2005 Nov 1
73 15050096 C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases. 2004 2
74 15129368 The interleukin-6/soluble interleukin-6 receptor system induces parathyroid hormone-related protein in human osteoblastic cells. 2004 Aug 2
75 15551657 Simvastatin induces death of multiple myeloma cell lines. 2004 Jul 1
76 15799170 Changes in serum interleukin-6 and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome and their responses to simvastatin. 2004 Nov 3
77 12826933 Simvastatin inhibits interleukin-6 release in human monocytes stimulated by C-reactive protein and lipopolysaccharide. 2003 Jun 1
78 12885745 Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy. 2003 Aug 19 1
79 12117737 Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients. 2002 Jul 1 3
80 11281303 The influence of short-term treatment with simvastatin on the inflammatory profile of patients with hypercholesterolaemia. 2001 Mar 1