| 1 |
34078115 | Impact of Interferons and Biological Drug Inhibitors of IL-2 and IL-6 on Small-Molecule Drug Metabolism Through the Cytochrome P450 System. | 2022 Feb |
1 |
| 2 |
34687147 | Inhibition of mevalonate metabolism by statins augments the immunoregulatory phenotype of vascular endothelial cells and inhibits the costimulation of CD4+ T cells. | 2022 Mar |
1 |
| 3 |
34812477 | Simvastatin inhibits the inflammation and oxidative stress of human neutrophils in sepsis via autophagy induction. | 2022 Jan |
1 |
| 4 |
31955966 | Influence of Statins on Circulating Inflammatory Cytokines in Patients With Abnormal Glucose Homeostasis: A Meta-analysis of Data From Randomized Controlled Trials. | 2020 Feb |
2 |
| 5 |
32418888 | Attenuation of the pro-inflammatory signature of lung cancer-derived mesenchymal stromal cells by statins. | 2020 Aug 1 |
2 |
| 6 |
32629602 | [The possible mechanisms of simvastatin on apoptosis of lung adenocarcinoma cells]. | 2020 Jul 7 |
1 |
| 7 |
29232287 | The Effects of Known Cardioprotective Drugs on Proinflammatory Cytokine Secretion From Human Coronary Artery Endothelial Cells. | 2019 May/Jun |
1 |
| 8 |
30288636 | Statins Inhibit Cytokines in a Dose-Dependent Response in Patients with Systemic Sclerosis. | 2019 Apr |
1 |
| 9 |
30312114 | Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models. | 2019 Feb |
1 |
| 10 |
30461427 | Proinflammatory and anti-inflammatory biomarkers in schizophrenia and influence of simvastatin on the interleukin-6. | 2019 Mar |
2 |
| 11 |
30887238 | Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations. | 2019 Mar 18 |
1 |
| 12 |
29389739 | Simvastatin Modulates Interaction Between Vascular Smooth Muscle Cell/Macrophage and TNF-α-Activated Endothelial Cell. | 2018 May |
1 |
| 13 |
30186882 | Effects of Systemic Simvastatin on the Concentrations of Visfatin, Tumor Necrosis Factor-α, and Interleukin-6 in Gingival Crevicular Fluid in Patients with Type 2 Diabetes and Chronic Periodontitis. | 2018 |
1 |
| 14 |
27003335 | Simvastatin inhibits the expression of inflammatory cytokines and cell adhesion molecules induced by LPS in human dental pulp cells. | 2017 Apr |
1 |
| 15 |
28601733 | Effect of 1.2% of simvastatin gel as a local drug delivery system on Gingival Crevicular Fluid interleukin-6 & interleukin-8 levels in non surgical treatment of chronic periodontitis patients. | 2017 Oct |
2 |
| 16 |
28713941 | Additive antitumor effects of celecoxib and simvastatin on head and neck squamous cell carcinoma in vitro. | 2017 Sep |
1 |
| 17 |
29250545 | Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation. | 2017 |
1 |
| 18 |
29285177 | Anti-inflammatory effects of Simvastatin in patients with acute intracerebral hemorrhage in an intensive care unit. | 2017 Dec |
1 |
| 19 |
26884290 | The effect of hypolipidemic treatment on monocyte cytokine release in different age groups of patients with type 2 diabetes and atherogenic dyslipidemia. | 2016 |
1 |
| 20 |
27086089 | Perioperative Simvastatin Therapy in Major Colorectal Surgery: A Prospective, Double-Blind Randomized Controlled Trial. | 2016 Aug |
2 |
| 21 |
27195204 | Effect of topical simvastatin (1.2 mg) on gingival crevicular fluid interleukin-6, interleukin-8 and interleukin-10 levels in chronic periodontitis - A clinicobiochemical study. | 2016 May-Aug |
2 |
| 22 |
27411707 | Simvastatin Treatment Modulates Mechanically-Induced Injury and Inflammation in Respiratory Epithelial Cells. | 2016 Dec |
1 |
| 23 |
27650878 | Oxidized Low-Density Lipoprotein (OxLDL)-Treated Dendritic Cells Promote Activation of T Cells in Human Atherosclerotic Plaque and Blood, Which Is Repressed by Statins: microRNA let-7c Is Integral to the Effect. | 2016 Sep 20 |
1 |
| 24 |
25374119 | Simvastatin attenuates angiotensin II‑induced inflammation and oxidative stress in human mesangial cells. | 2015 Feb |
1 |
| 25 |
25704622 | The Effect of Simvastatin on Infection-Induced Inflammatory Response of Human Fetal Membranes. | 2015 Jul |
1 |
| 26 |
25866715 | Anti-inflammatory effect of simvastatin in hemodialysis patients. | 2015 Feb |
1 |
| 27 |
26020489 | Tocilizumab unmasks a stage-dependent interleukin-6 component in statin-induced apoptosis of metastatic melanoma cells. | 2015 Aug |
4 |
| 28 |
26136131 | Comparison of the effects of hypolipidemic treatment on monocyte proinflammatory cytokine release in men and women with type 2 diabetes and atherogenic dyslipidemia. | 2015 |
3 |
| 29 |
26550333 | Different regulation of Toll-like receptor 4 expression on blood CD14(+) monocytes by simvastatin in patients with sepsis and severe sepsis. | 2015 |
2 |
| 30 |
26559850 | Simvastatin ameliorates experimental autoimmune encephalomyelitis by inhibiting Th1/Th17 response and cellular infiltration. | 2015 Dec |
1 |
| 31 |
24419251 | Simvastatin inhibits cytokines in a dose response in patients with rheumatoid arthritis. | 2014 Apr |
2 |
| 32 |
24684779 | Synergistic anti-inflammatory effect: simvastatin and pioglitazone reduce inflammatory markers of plasma and epicardial adipose tissue of coronary patients with metabolic syndrome. | 2014 Mar 31 |
2 |
| 33 |
24788303 | Simvastatin modulates cellular components in influenza A virus-infected cells. | 2014 Jul |
1 |
| 34 |
25257410 | Anti-inflammatory effects of simvastatin in patients with chronic heart failure. | 2014 Sep |
1 |
| 35 |
22915623 | Simvastatin inhibits the pro-inflammatory and pro-thrombotic effects of IL-17 and TNF-α on endothelial cells. | 2013 May |
2 |
| 36 |
22922248 | Simvastatin prevents the induction of interleukin-6 gene expression by titanium particles in human osteoblastic cells. | 2013 Jan |
3 |
| 37 |
23013513 | Effects of simvastatin and ezetimibe on interleukin-6 and high-sensitivity C-reactive protein. | 2013 Feb |
3 |
| 38 |
23159435 | Monocyte-suppressing effects of simvastatin in patients with isolated hypertriglyceridemia. | 2013 Apr |
1 |
| 39 |
23331562 | Statins enhance the effects of corticosteroids on the balance between regulatory T cells and Th17 cells. | 2013 Feb |
1 |
| 40 |
23588308 | A physiologically based pharmacokinetic modeling approach to predict disease-drug interactions: suppression of CYP3A by IL-6. | 2013 Aug |
1 |
| 41 |
23690956 | Simvastatin inhibits renal cancer cell growth and metastasis via AKT/mTOR, ERK and JAK2/STAT3 pathway. | 2013 |
1 |
| 42 |
22796581 | Simvastatin reduces myocardial injury undergoing noncoronary artery cardiac surgery: a randomized controlled trial. | 2012 Sep |
1 |
| 43 |
22950641 | The effects of vitamin E-coated membrane dialyzer compared to simvastatin in patients on chronic hemodialysis. | 2012 |
1 |
| 44 |
23042198 | Simvastatin protects against T cell immune dysfunction in abdominal sepsis. | 2012 Nov |
2 |
| 45 |
23062767 | Effect of simvastatin or its combination with ezetimibe on Toll-like receptor expression and lipopolysaccharide - induced cytokine production in monocytes of hypercholesterolemic patients. | 2012 Dec |
2 |
| 46 |
20158569 | Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures. | 2011 Apr |
1 |
| 47 |
21276586 | Effect of simvastatin and fenofibrate on cytokine release and systemic inflammation in type 2 diabetes mellitus with mixed dyslipidemia. | 2011 Apr 1 |
1 |
| 48 |
21440087 | Statins as modulators of colon cancer cells induced cytokine secretion by human PBMC. | 2011 Mar-Jun |
1 |
| 49 |
21477202 | A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction. | 2011 Jun |
2 |
| 50 |
20150839 | The influence of simvastatin on selected inflammatory markers in patients with chronic obstructive pulmonary disease. | 2010 |
1 |