| 1 |
35536531 | Tofacitinib enhances IGF1 via inhibiting STAT6 transcriptionally activated-miR-425-5p to ameliorate inflammation in RA-FLS. | 2022 May 10 |
1 |
| 2 |
35631449 | Tofacitinib May Inhibit Myofibroblast Differentiation from Rheumatoid-Fibroblast-like Synoviocytes Induced by TGF-β and IL-6. | 2022 May 18 |
1 |
| 3 |
32909045 | The JAK Inhibitor Tofacitinib Rescues Intestinal Barrier Defects Caused by Disrupted Epithelial-macrophage Interactions. | 2021 Mar 5 |
1 |
| 4 |
33165509 | Impaired IFN-γ-dependent STAT3 Activation Is Associated With Dysregulation of Regulatory and Inflammatory Signaling in Monocytes of Ulcerative Colitis Patients. | 2021 May 17 |
1 |
| 5 |
33216905 | Tofacitinib counteracts IL-6 overexpression induced by deficient autophagy: implications in Sjögren's syndrome. | 2021 Apr 6 |
2 |
| 6 |
33337450 | STAT3/IL-6 dependent induction of inflammatory response in osteoblast and osteoclast formation in nanoscale wear particle-induced aseptic prosthesis loosening. | 2021 Feb 21 |
1 |
| 7 |
33495807 | Downregulation of miR‑409‑3p suppresses LPS‑induced inflammation in human bronchial epithelial cells through SOCS3/JAK1/STAT3 signaling: The implication for bronchopneumonia. | 2021 Mar |
1 |
| 8 |
33587766 | Rapidly progressive alopecia areata totalis in a COVID-19 patient, unresponsive to tofacitinib. | 2021 Jul |
1 |
| 9 |
33871355 | Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses. | 2021 Apr 19 |
1 |
| 10 |
33899926 | Lymphocyte modulation by tofacitinib in patients with rheumatoid arthritis. | 2021 Aug |
2 |
| 11 |
34052462 | The JAK inhibitor Tofacitinib inhibits structural damage in osteoarthritis by modulating JAK1/TNF-alpha/IL-6 signaling through Mir-149-5p. | 2021 Oct |
3 |
| 12 |
34107055 | Tofacitinib therapy intercepts macrophage metabolic reprogramming instigated by SARS-CoV-2 Spike protein. | 2021 Sep |
1 |
| 13 |
34660145 | Tofacitinib Treatment in Patients With Active COVID-19 Infection. | 2021 Sep |
1 |
| 14 |
31448433 | Preferential Inhibition of JAK1 Relative to JAK3 by Upadacitinib: Exposure-Response Analyses of Ex Vivo Data From 2 Phase 1 Clinical Trials and Comparison to Tofacitinib. | 2020 Feb |
5 |
| 15 |
31560043 | Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory Phenotype. | 2020 Feb 11 |
1 |
| 16 |
32808031 | The JAK1/3 inhibitor tofacitinib suppresses T cell homing and activation in chronic intestinal inflammation. | 2020 Aug 18 |
1 |
| 17 |
30984167 | Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib. | 2019 |
1 |
| 18 |
31780862 | Changes in Serum Cytokines May Predict Therapeutic Efficacy of Tofacitinib in Rheumatoid Arthritis. | 2019 |
1 |
| 19 |
28927890 | Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment. | 2018 Feb |
1 |
| 20 |
29106440 | Identification of PMN-released mutagenic factors in a co-culture model for colitis-associated cancer. | 2018 Feb 9 |
1 |
| 21 |
29162613 | The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes. | 2018 Feb |
1 |
| 22 |
29790294 | JAK/STAT Blockade Alters Synovial Bioenergetics, Mitochondrial Function, and Proinflammatory Mediators in Rheumatoid Arthritis. | 2018 Dec |
2 |
| 23 |
28570653 | Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma. | 2017 |
2 |
| 24 |
28752178 | Inhibitory effect of JAK inhibitor on mechanical stress-induced protease expression by human articular chondrocytes. | 2017 Nov |
1 |
| 25 |
26353790 | Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors. | 2016 Jan |
1 |
| 26 |
27003097 | An Update on Calcineurin Inhibitor-Free Regimens: The Need Persists, but the Landscape has Changed. | 2016 Apr |
1 |
| 27 |
24342887 | Effects of topical Janus kinase inhibition on ocular surface inflammation and immunity. | 2014 Feb |
1 |
| 28 |
24665995 | Effects of Janus kinase inhibitor tofacitinib on circulating serum amyloid A and interleukin-6 during treatment for rheumatoid arthritis. | 2014 Feb |
4 |
| 29 |
22121136 | The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon. | 2012 Mar |
1 |
| 30 |
22147632 | The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells. | 2012 Jun |
4 |
| 31 |
22460142 | In vitro and in vivo analysis of a JAK inhibitor in rheumatoid arthritis. | 2012 Apr |
1 |
| 32 |
22941906 | Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors. | 2012 Dec |
1 |