Pentoxifylline

interleukin 6 ; Homo sapiens







53 Article(s)
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1 34666302 Pentoxifylline effects on hospitalized patients with COVID19: A randomized, double-blind clinical trial. 2021 Dec 3
2 32706089 Potential usefulness of pentoxifylline, a non-specific phosphodiesterase inhibitor with anti-inflammatory, anti-thrombotic, antioxidant, and anti-fibrogenic properties, in the treatment of SARS-CoV-2. 2020 Jul 1
3 29715306 Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. 2018 2
4 30205379 The Phosphodiesterase Inhibitor Pentoxifylline as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients: A Proof-of-Concept, Randomized, Double-Blind, Placebo-Controlled Trial. 2018 1
5 28072760 Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns. 2017 May 1
6 28288151 Pentoxifylline modulates LPS-induced hyperinflammation in monocytes of preterm infants in vitro. 2017 Aug 1
7 29233145 Suppression of interleukin-6 increases enterovirus A71 lethality in mice. 2017 Dec 12 1
8 25880052 Preoperative oral pentoxifylline in case of coronary artery bypass grafting with left ventricular dysfunction (ejection fraction equal to/less than 30%). 2015 1
9 23639230 Pentoxifylline inhibits melanoma tumor growth and angiogenesis by targeting STAT3 signaling pathway. 2013 Jun 1
10 21968012 Pentoxifylline decreases serum levels of tumor necrosis factor alpha, interleukin 6 and C-reactive protein in hemodialysis patients: results of a randomized double-blind, controlled clinical trial. 2012 May 2
11 23023149 Genipin-crosslinked chitosan scaffolds and its efficacy in releasing anti-inflammatory medicine. 2012 2
12 20191310 Alginate-crosslinked chitosan scaffolds as pentoxifylline delivery carriers. 2010 May 1
13 20370329 Controlled release of pentoxifylline from porous chitosan-pectin scaffolds. 2010 Jul 2
14 20470305 Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease. 2010 Apr 6
15 20799759 Pentoxifylline in preterm neonates: a systematic review. 2010 Oct 1 1
16 21037437 Effects of pentoxifylline on liver regeneration: a double-blinded, randomized, controlled trial in 101 patients undergoing major liver resection. 2010 Nov 4
17 19220089 Effect of intravenous pentoxifylline in inflammatory response in patients undergoing nephrolithotomy. 2009 Feb 1
18 19373973 Randomized study of the effect of pentoxifylline or octreotide on serum levels of TNF-alpha and IL-6 after endoscopic retrograde cholangiopancreatography. 2009 May 1
19 19468304 Leishmania infantum amastigotes enhance HIV-1 production in cocultures of human dendritic cells and CD4 T cells by inducing secretion of IL-6 and TNF-alpha. 2009 May 26 1
20 18464882 Preoperative oral administration of pentoxifylline ameliorates respiratory index after cardiopulmonary bypass through decreased production of IL-6. 2008 Apr 1
21 17112855 Effects of pentoxifylline on the cytokines that may play a role in rejection and resistive index in renal transplant recipients. 2006 Nov 2
22 18172961 [The role of pentoxifylline in nitrogen conversion in patients suffering from diabetic phlegmona of the foot]. 2006 Oct 1
23 14984727 Pentoxifylline in ischemic, hypertensive and idiopathic-dilated cardiomyopathy: effects on left-ventricular function, inflammatory cytokines and symptoms. 2004 Mar 1 1
24 15502050 Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption, and improving recovery of bowel function in patients undergoing colorectal cancer surgery. 2004 Nov 2
25 15591651 Pentoxifylline does not affect nociception if administered postoperatively. 2004 Sep-Oct 2
26 15727386 Effect of pentoxifylline on tumor necrosis factor-alpha and interleukin-6 levels in neonatal sepsis. 2004 Aug 2
27 12794024 Pentoxifyllin attenuates the systemic inflammatory response induced during isolated limb perfusion with recombinant human tumor necrosis factor-alpha and melphalan. 2003 Jun 1
28 11805217 Immunopharmacological potential of selective phosphodiesterase inhibition. I. Differential regulation of lipopolysaccharide-mediated proinflammatory cytokine (interleukin-6 and tumor necrosis factor-alpha) biosynthesis in alveolar epithelial cells. 2002 Feb 1
29 12375150 A child with simple ulcer of the colon effectively treated with the combination of prednisolone, azathioprine, and pentoxifylline. 2002 2
30 11301047 Differential effects of pentoxifylline on the hepatic inflammatory response in porcine liver cell cultures. Increase in inducible nitric oxide synthase expression. 2001 May 1 4
31 11520766 Pentoxifylline influences the autocrine function of organ cultured donor corneas and enhances endothelial cell survival. 2001 Sep 2
32 11583728 Differential lipogenic effects of cilostazol and pentoxifylline in patients with intermittent claudication: potential role for interleukin-6. 2001 Oct 2
33 11007619 Effect of anti-inflammatory medication on monocyte response to titanium particles. 2000 Dec 5 2
34 10321674 Effect of the immunomodulating agent, pentoxifylline, in the treatment of sepsis in prematurely delivered infants: a placebo-controlled, double-blind trial. 1999 Apr 3
35 10416955 Interleukin-6 as a central mediator of cardiovascular risk associated with chronic inflammation, smoking, diabetes, and visceral obesity: down-regulation with essential fatty acids, ethanol and pentoxifylline. 1999 May 2
36 10464849 The differential effect of pentoxifylline on cytokine production by alveolar macrophages and its clinical implications. 1999 Jan 2
37 9525624 Human parvovirus B19 nonstructural (NS1) protein induces apoptosis in erythroid lineage cells. 1998 Apr 1
38 9546416 Effect of pentoxifylline on cytokine patterns in the therapy of complicated Plasmodium falciparum malaria. 1998 Mar 3
39 9160101 Inhibition of LPS and Plasmodium falciparum induced cytokine secretion by pentoxifylline and two analogues. 1997 May 1
40 9378738 Modulation of the production of cytokines in titanium-stimulated human peripheral blood monocytes by pharmacological agents. The role of cAMP-mediated signaling mechanisms. 1997 Oct 1
41 9408298 Relevance of cytokine production to infected pancreatic necrosis. 1997 2
42 9172017 Differential regulation of TNF alpha, IL-1 beta, IL-6, IL-8, TNF beta, and IL-10 by pentoxifylline. 1996 Dec 4
43 8548203 Effects of pentoxifyllin and PentaglobinO on TNF and IL-6 production in septic patients. 1995 1
44 8575836 Monocyte-mediated regulation of antigen-driven IFN gamma production by T cells. The role of endogenously produced TNF. 1995 Nov 1
45 8699873 Leukocyte activation study during occlusive arterial disease of the lower limb: effect of pentoxifylline infusion. 1995 1
46 7835945 Pentoxifylline in vivo down-regulates the release of IL-1 beta, IL-6, IL-8 and tumour necrosis factor-alpha by human peripheral blood mononuclear cells. 1994 Oct 8
47 8015309 Pentoxifylline attenuates oxygen-induced lung injury. 1994 Jun 4
48 7505000 In vitro immunomodulatory effects of pentoxifylline. 1993 Aug 1
49 8393800 Interleukin-6 production in "normal" and HTLV-1 tax-expressing brain-specific endothelial cells. 1993 Aug 1
50 8500916 Production of interleukin-6 by human and murine mononuclear leukocytes stimulated with Plasmodium antigens is enhanced by pentoxifylline, and tumor necrosis factor secretion is reduced. 1993 Jun 2