NAD

nicotinamide nucleotide adenylyltransferase 1 ; Homo sapiens







58 Article(s)
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1 35408818 NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy. 2022 Mar 22 1
2 34290089 Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells. 2021 Jul 7
3 34445574 NMNAT1 Is a Survival Factor in Actinomycin D-Induced Osteosarcoma Cell Death. 2021 Aug 18 3
4 34866305 The key role of the NAD biosynthetic enzyme nicotinamide mononucleotide adenylyltransferase in regulating cell functions. 2021 Dec 5 1
5 34878972 Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons. 2021 Dec 8 1
6 34919052 NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis. 2021 Dec 17 2
7 31988240 A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus. 2020 Mar 13 2
8 32392755 Targeting Nuclear NAD+ Synthesis Inhibits DNA Repair, Impairs Metabolic Adaptation and Increases Chemosensitivity of U-2OS Osteosarcoma Cells. 2020 May 7 3
9 32533184 An Alu-mediated duplication in NMNAT1, involved in NAD biosynthesis, causes a novel syndrome, SHILCA, affecting multiple tissues and organs. 2020 Aug 3 1
10 32775493 Gene Therapy Preserves Retinal Structure and Function in a Mouse Model of NMNAT1-Associated Retinal Degeneration. 2020 Sep 11 4
11 33107823 SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration. 2020 Oct 27 1
12 33330464 NAD+ Metabolism Regulates Preadipocyte Differentiation by Enhancing α-Ketoglutarate-Mediated Histone H3K9 Demethylation at the PPARγ Promoter. 2020 1
13 30951610 Chemoenzymatic Preparation of 4'-Thioribose NAD. 2019 Jun 3
14 31136762 Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence. 2019 Oct 4
15 31754102 NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome. 2019 Nov 21 2
16 29748257 Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. 2018 May 11 1
17 30166529 Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation. 2018 Aug 30 3
18 28445802 NMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector. 2017 Jun 2
19 29029387 The β-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation. 2017 Sep 12 2
20 26018082 Characterization of Leber Congenital Amaurosis-associated NMNAT1 Mutants. 2015 Jul 10 1
21 23737528 The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription. 2013 Jul 19 3
22 24155910 Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria. 2013 2
23 22334709 Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase. 2012 Apr 6 3
24 22842227 NMNAT1 mutations cause Leber congenital amaurosis. 2012 Sep 4
25 22842229 Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy. 2012 Sep 2
26 22842230 Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration. 2012 Sep 1
27 21517775 NMN/NaMN adenylyltransferase (NMNAT) and NAD kinase (NADK) inhibitors: chemistry and potential therapeutic applications. 2011 1
28 21517776 NMNAT expression and its relation to NAD metabolism. 2011 4
29 19879981 SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions. 2010 Aug 2
30 20388704 Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. 2010 Jun 11 1
31 20457531 Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells. 2010 Jun 15 4
32 20591898 Nicotinate/nicotinamide mononucleotide adenyltransferase-mediated regulation of NAD biosynthesis protects guard cells from reactive oxygen species in ABA-mediated stomatal movement in Arabidopsis. 2010 Aug 3
33 20954240 Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship. 2010 Dec 2
34 19403820 Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. 2009 Apr 29 2
35 19448972 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme. 2009 Sep 3
36 19478080 Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters. 2009 Jul 24 5
37 18275811 Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism. 2008 Feb 1
38 17402747 Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. 2007 Apr 24 1
39 16371511 The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. 2006 Mar 1
40 16118205 Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. 2005 Oct 28 5
41 16247974 Synthesis and biological evaluation of NAD analogs as human pyridine nucleotide adenylyltransferase inhibitors. 2005 1
42 14516279 Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas. 2004 Jan 15 2
43 15078171 Structure and function of nicotinamide mononucleotide adenylyltransferase. 2004 Apr 1
44 16857098 NAD+ metabolism in lymphocytes of patients affected by B-cell chronic lymphocytic leukaemia. 2004 Sep-Dec 6
45 14565298 Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation. 2003 May-Aug 1
46 11751893 Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis. 2002 Mar 8 2
47 11752792 Crystallization and preliminary X-ray analysis of human nicotinamide mononucleotide adenylyltransferase (NMNAT). 2002 Jan 2
48 11788603 Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. 2002 Apr 12 3
49 11959140 Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN. 2002 Apr 10 1
50 11966438 Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase. 2002 Apr 2