deoxyguanosine triphosphate

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 ; Homo sapiens







25 Article(s)
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1 33907561 Dual roles of SAMHD1 in tumor development and chemoresistance to anticancer drugs. 2021 Jun 1
2 31914608 SAMHD1-deficient fibroblasts from Aicardi-Goutières Syndrome patients can escape senescence and accumulate mutations. 2020 Jan 1
3 32402273 SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP. 2020 May 12 1
4 30181218 Interplay of ancestral non-primate lentiviruses with the virus-restricting SAMHD1 proteins of their hosts. 2018 Oct 19 1
5 27991919 SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia. 2017 Feb 1
6 28502830 With me or against me: Tumor suppressor and drug resistance activities of SAMHD1. 2017 Aug 4
7 25760601 The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP. 2015 Mar 2
8 26342080 The Deoxynucleoside Triphosphate Triphosphohydrolase Activity of SAMHD1 Protein Contributes to the Mitochondrial DNA Depletion Associated with Genetic Deficiency of Deoxyguanosine Kinase. 2015 Oct 23 5
9 26438820 Structural Insights into the High-efficiency Catalytic Mechanism of the Sterile α-Motif/Histidine-Aspartate Domain-containing Protein. 2015 Dec 4 2
10 25038827 The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. 2014 Aug 2
11 25267621 Structural basis of cellular dNTP regulation by SAMHD1. 2014 Oct 14 3
12 25288794 Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates. 2014 Nov 21 2
13 23371319 Single-stranded nucleic acids promote SAMHD1 complex formation. 2013 Jun 2
14 23426366 Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection. 2013 Apr 12 1
15 23442224 Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection. 2013 Feb 25 1
16 23677995 HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation. 2013 Jun 28 2
17 23858451 The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells. 2013 Aug 27 1
18 23880768 GTP is the primary activator of the anti-HIV restriction factor SAMHD1. 2013 Aug 30 6
19 23966382 Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1. 2013 Nov 1
20 24141705 Mechanism of allosteric activation of SAMHD1 by dGTP. 2013 Nov 3
21 24217394 Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase. 2013 6
22 24219908 Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1. 2013 Nov 12 2
23 22978176 [Research progress of the anti-HIV activity of SAMHD1]. 2012 Jun 1
24 22056990 HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. 2011 Nov 6 2
25 22069334 Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase. 2011 Dec 23 2