| 1 |
35101444 | Mitochondrial respiratory chain dysfunction alters ER sterol sensing and mevalonate pathway activity. | 2022 Mar |
1 |
| 2 |
35495674 | LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation. | 2022 |
1 |
| 3 |
31875875 | Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import. | 2020 Feb 1 |
1 |
| 4 |
32705598 | Proprotein Convertase Subtilisin/Kexin-Type 9 and Lipid Metabolism. | 2020 |
1 |
| 5 |
32974183 | Targeting SREBP-2-Regulated Mevalonate Metabolism for Cancer Therapy. | 2020 |
1 |
| 6 |
30864739 | Hydrogen sulfide inhibits PCSK9 expression through the PI3K/Akt‑SREBP‑2 signaling pathway to influence lipid metabolism in HepG2 cells. | 2019 May |
1 |
| 7 |
31303399 | The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair. | 2019 Aug 20 |
1 |
| 8 |
31455613 | Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing. | 2019 Oct |
1 |
| 9 |
29353227 | The natural history of phytosterolemia: Observations on its homeostasis. | 2018 Feb |
2 |
| 10 |
28202541 | Coordinate Regulation of Yeast Sterol Regulatory Element-binding Protein (SREBP) and Mga2 Transcription Factors. | 2017 Mar 31 |
1 |
| 11 |
26028026 | Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP. | 2016 Mar 10 |
1 |
| 12 |
26798145 | Srebp2: A master regulator of sterol and fatty acid synthesis. | 2016 Mar |
1 |
| 13 |
26938778 | An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway. | 2016 Mar |
1 |
| 14 |
26015437 | New CETP inhibitor K-312 reduces PCSK9 expression: a potential effect on LDL cholesterol metabolism. | 2015 Jul 15 |
1 |
| 15 |
26353928 | Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death. | 2015 Sep 29 |
1 |
| 16 |
24770487 | Protein phosphatase 2A (PP2A) regulates low density lipoprotein uptake through regulating sterol response element-binding protein-2 (SREBP-2) DNA binding. | 2014 Jun 13 |
1 |
| 17 |
22274626 | MicroRNAs regulating lipid metabolism in atherogenesis. | 2012 Apr |
1 |
| 18 |
21408089 | Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. | 2011 Mar |
1 |
| 19 |
21459322 | Genome-wide localization of SREBP-2 in hepatic chromatin predicts a role in autophagy. | 2011 Apr 6 |
2 |
| 20 |
21527438 | N-glycosylation controls trafficking, zymogen activation and substrate processing of proprotein convertases PC1/3 and subtilisin kexin isozyme-1. | 2011 Oct |
1 |
| 21 |
22012398 | Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. | 2011 Oct 19 |
1 |
| 22 |
22095132 | ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter. | 2011 Dec 6 |
3 |
| 23 |
20138239 | Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element, a GC-box, and an inverted CCAAT-box. | 2010 May |
1 |
| 24 |
19706601 | The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage. | 2009 Oct 16 |
5 |
| 25 |
20041144 | Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3. | 2009 Dec 30 |
1 |
| 26 |
18032389 | Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis. | 2008 Jan 25 |
1 |
| 27 |
18095660 | Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis. | 2008 Jan 15 |
1 |
| 28 |
18550691 | The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells. | 2008 Sep |
1 |
| 29 |
18676367 | Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha. | 2008 Sep 26 |
1 |
| 30 |
17008555 | Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2. | 2007 Jan |
1 |
| 31 |
17604677 | Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2. | 2007 |
1 |
| 32 |
16787396 | Dynamin is involved in endolysosomal cholesterol delivery to the endoplasmic reticulum: role in cholesterol homeostasis. | 2006 Jul |
2 |
| 33 |
15358760 | Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism. | 2004 Nov 19 |
1 |
| 34 |
12842885 | Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs. | 2003 Sep 12 |
1 |
| 35 |
11085986 | Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells. | 2001 Feb 9 |
1 |
| 36 |
11283257 | Dimerization of sterol regulatory element-binding protein 2 via the helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin beta. | 2001 Apr |
1 |
| 37 |
11348878 | 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation. | 2001 May |
1 |
| 38 |
9989262 | The physiological role of sterol regulatory element-binding protein-2 in cultured human cells. | 1999 Jan 4 |
2 |
| 39 |
9139737 | Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2. | 1997 May 9 |
1 |
| 40 |
8900111 | Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2. | 1996 Oct 25 |
1 |
| 41 |
7862668 | Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver. | 1995 Feb 14 |
2 |
| 42 |
7903453 | SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. | 1993 Dec 15 |
1 |