Sildenafil Citrate

phosphodiesterase 5A ; Homo sapiens







530 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
401 16247643 Phosphodiesterase inhibitors in female sexual dysfunction. 2005 Dec 2
402 16273417 Clinical update on phosphodiesterase type-5 inhibitors for erectile dysfunction. 2005 Dec 1
403 16273418 Treating erectile dysfunction by endothelial rehabilitation with phosphodiesterase 5 inhibitors. 2005 Dec 2
404 16287454 An open-label, multicentre, randomized, crossover study comparing sildenafil citrate and tadalafil for treating erectile dysfunction in men naïve to phosphodiesterase 5 inhibitor therapy. 2005 Dec 1
405 16292559 Cyclic AMP-specific and cyclic GMP-specific phosphodiesterase isoenzymes in human cavernous arteries--immunohistochemical distribution and functional significance. 2005 Dec 1
406 16339700 Therapeutic approaches to pulmonary hypertension in hemoglobinopathies: Efficacy and safety of sildenafil in the treatment of severe pulmonary hypertension in patients with hemoglobinopathy. 2005 1
407 16378510 Phosphodiesterase type 5 inhibitors: molecular pharmacology and interactions with other phosphodiesterases. 2005 2
408 16387565 Cardiac safety in clinical trials of phosphodiesterase 5 inhibitors. 2005 Dec 26 1
409 16387566 Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions. 2005 Dec 26 2
410 16422865 Enhancement of both EDHF and NO/cGMP pathways is necessary to reverse erectile dysfunction in diabetic rats. 2005 May 1
411 16985896 PDE-5 Inhibitor Therapy for Erectile Dysfunction Secondary to Nerve-Sparing Radical Retropubic Prostatectomy. 2005 1
412 14871543 Cardioprotection with phosphodiesterase-5 inhibition--a novel preconditioning strategy. 2004 Feb 3
413 15075013 Treatment of erectile dysfunction. 2004 Apr 1
414 15080987 Synthesis and phosphodiesterase 5 inhibitory activity of new sildenafil analogues containing a phosphonate group in the 5(')-sulfonamide moiety of phenyl ring. 2004 May 3 3
415 15083994 Pharmacokinetics, pharmacodynamics, and efficacy of phosphodiesterase type 5 inhibitors. 2004 Mar 2
416 15093609 The cGMP-binding, cGMP-specific phosphodiesterase (PDE5): intestinal cell expression, regulation and role in fluid secretion. 2004 Jun 3
417 15115191 Phosphodiesterase type 5 inhibitor differentiation based on selectivity, pharmacokinetic, and efficacy profiles. 2004 Apr 4
418 15148932 [Comparison of efficacy and safety of phosphodiesterase type 5 inhibitors in the treatment of erectile dysfunction]. 2004 Apr 2
419 15155143 Emerging oral drugs for erectile dysfunction. 2004 May 2
420 15175637 Cardiovascular effects of sildenafil in hypertensive men with erectile dysfunction and different alleles of the type 5 cGMP-specific phosphodiesterase (PDE5). 2004 Oct 2
421 15183543 The impact of sildenafil on molecular science and sexual health. 2004 Jul 3
422 15194181 Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension. 2004 Jun 16 1
423 15197447 [Erectile dysfunction. New drugs with special consideration of the PDE 5 inhibitors]. 2004 Jul 1
424 15213306 Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation. 2004 Jul 3
425 15223851 Cardiovascular parameter changes in patients with erectile dysfunction using pde-5 inhibitors: a study with sildenafil and vardenafil. 2004 Jul-Aug 1
426 15224127 Mechanisms of action of PDE5 inhibition in erectile dysfunction. 2004 Jun 1
427 15224129 Potency, selectivity, and consequences of nonselectivity of PDE inhibition. 2004 Jun 1
428 15224132 Implications of PDE4 structure on inhibitor selectivity across PDE families. 2004 Jun 2
429 15260511 Future options for combination therapy in the management of erectile dysfunction in older men. 2004 1
430 15281210 [Erectile function disorders. Epidemiology, physiology, etiology, diagnosis and therapy]. 2004 Jun 1
431 15295092 Postnatal maturation of phosphodiesterase 5 (PDE5) in piglet pulmonary arteries: activity, expression, effects of PDE5 inhibitors, and role of the nitric oxide/cyclic GMP pathway. 2004 Oct 1
432 15295684 [Long-term effects of sildenafil in a patient with scleroderma-associated pulmonary hypertension and Raynaud's syndrome]. 2004 Aug 13 1
433 15312980 Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5). 2004 Nov 6
434 15322323 Sildenafil improves cutaneous microcirculation in patients with coronary artery disease: a monocentric, prospective, double-blind, placebo-controlled, randomized cross-over study. 2004 1
435 15333581 The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels. 2004 Sep 1
436 15371988 The effect of sildenafil on gastric emptying in patients with end-stage renal failure and symptoms of gastroparesis. 2004 Sep 1
437 15464333 Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study. 2004 Oct 6 4
438 15464535 Sildenafil: emerging cardiovascular indications. 2004 Oct 4
439 15466636 Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy. 2004 Oct 12 2
440 15475488 Influence of sildenafil on gastric sensorimotor function in humans. 2004 Nov 1
441 15476742 Absence of clinically important HERG channel blockade by three compounds that inhibit phosphodiesterase 5--sildenafil, tadalafil, and vardenafil. 2004 Oct 19 1
442 15497717 [Pharmacodynamics and pharmacokinetics of vardenafil in patients with erectile dysfunction]. 2004 Sep 1
443 15522526 Analysis of undeclared synthetic phosphodiesterase-5 inhibitors in dietary supplements and herbal matrices by LC-ESI-MS and LC-UV. 2004 Nov 15 2
444 15537369 New treatment options for erectile dysfunction in patients with diabetes mellitus. 2004 1
445 15560162 [Viagra, cialis, impase--which of them, to whom, when and how?]. 2004 Sep-Oct 1
446 15881813 Bioequivalence study of sildenafil citrate tablets in healthy human volunteers. 2004 Nov 4
447 21224902 Pharmacotherapy of sexual dysfunctions : current status. 2004 Jul 1
448 12477710 Migraine can be induced by sildenafil without changes in middle cerebral artery diameter. 2003 Jan 2
449 12554648 PDE5 is converted to an activated state upon cGMP binding to the GAF A domain. 2003 Feb 3 1
450 12614192 Long-term use of sildenafil. 2003 Mar 2