Sildenafil Citrate

phosphodiesterase 5A ; Homo sapiens







530 Article(s)
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51 31248114 Biphasic Effect of Sildenafil on Energy Sensing is Mediated by Phosphodiesterases 2 and 3 in Adipocytes and Hepatocytes. 2019 Jun 19 2
52 31311394 Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts. 2019 Aug 6 2
53 31350821 The first-generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue. 2019 Nov 1
54 31409013 Intervening with the Nitric Oxide Pathway to Alleviate Pulmonary Hypertension in Pulmonary Vein Stenosis. 2019 Aug 12 1
55 31463257 Investigating the effect of sildenafil on improving lung function and quality of life in the patients with severe asthma. 2019 Jul 1
56 29089445 Novel imaging of the prostate reveals spontaneous gland contraction and excretory duct quiescence together with different drug effects. 2018 Mar 1
57 29467656 Sublingual Administration of Sildenafil Oro-dispersible Film: New Profiles of Drug Tolerability and Pharmacokinetics for PDE5 Inhibitors. 2018 1
58 29511676 Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding. 2018 2
59 29667180 PDE5 inhibitors - pharmacology and clinical applications 20 years after sildenafil discovery. 2018 Jul 3
60 29694963 Treatment of Macular Degeneration with Sildenafil: Results of a Two-Year Trial. 2018 1
61 29735634 Evaluation of Sildenafil and Tadalafil for Reversing Constriction of Fetal Arteries in a Human Placenta Perfusion Model. 2018 Jul 3
62 29901310 [Current role of sildenafil in the management of erectile dysfunction]. 2018 May 1
63 30023062 The effect of sildenafil on gastric motility and satiation in healthy controls. 2018 Jul 1
64 30148362 Optimization of Chromeno[2,3- c]pyrrol-9(2 H)-ones as Highly Potent, Selective, and Orally Bioavailable PDE5 Inhibitors: Structure-Activity Relationship, X-ray Crystal Structure, and Pharmacodynamic Effect on Pulmonary Arterial Hypertension. 2018 Sep 27 1
65 30292404 Novel effect of sildenafil on hair growth. 2018 Nov 2 2
66 30352768 Role of neuronal nitric oxide synthase (nNOS) in Duchenne and Becker muscular dystrophies - Still a possible treatment modality? 2018 Nov 2
67 30381311 TADAFER II: Tadalafil treatment for fetal growth restriction - a study protocol for a multicenter randomised controlled phase II trial. 2018 Oct 30 2
68 30548639 Tadalafil: 15 years' journey in male erectile dysfunction and beyond. 2018 Dec 13 2
69 30705876 Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems. 2018 2
70 27101805 A randomized clinical trial investigating treatment choice in Chinese men receiving sildenafil citrate and tadalafil for treating erectile dysfunction. 2017 Jul-Aug 2
71 27338710 Adulteration of herbal sexual enhancers and slimmers: The wish for better sexual well-being and perfect body can be risky. 2017 Oct 2
72 27581752 In silico design of novel hERG-neutral sildenafil-like PDE5 inhibitors. 2017 Oct 2
73 27979549 Re: PDE5A Polymorphisms Influence on Sildenafil Treatment Success. 2017 Jan 1
74 27979766 Nebulized solid lipid nanoparticles for the potential treatment of pulmonary hypertension via targeted delivery of phosphodiesterase-5-inhibitor. 2017 Jan 30 2
75 28013386 Potentiation of the NO-cGMP pathway and blood flow responses during dynamic exercise in healthy humans. 2017 Feb 1
76 28123846 Phosphodiesterase-5 inhibition suppresses colonic inflammation-induced tumorigenesis via blocking the recruitment of MDSC. 2017 2
77 28139291 Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction: Pharmacology and Clinical Impact of the Sildenafil Citrate Orodispersible Tablet Formulation. 2017 Feb 2
78 28150511 Investigation of PDE5/PDE6 and PDE5/PDE11 selective potent tadalafil-like PDE5 inhibitors using combination of molecular modeling approaches, molecular fingerprint-based virtual screening protocols and structure-based pharmacophore development. 2017 Dec 2
79 28211580 Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux. 2017 Jun 2
80 28243607 Treatment with Sildenafil and Donepezil Improves Angiogenesis in Experimentally Induced Critical Limb Ischemia. 2017 2
81 28316997 Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients. 2017 2
82 28394532 [Phosphodiesterase type 5 inhibitors in the treatment of erectile dysfunction: past, present and future]. 2017 Apr 1
83 28496549 Phosphodiesterase-5 Inhibitors Improve Clinical Outcomes, Exercise Capacity and Pulmonary Hemodynamics in Patients With Heart Failure With Reduced Left Ventricular Ejection Fraction: A Meta-Analysis. 2017 Jun 2
84 28533270 Classical activation of macrophages and vardenafil. 2017 Jun 1 2
85 28587325 Sildenafil suppresses the proliferation and enhances the apoptosis of hemangioma endothelial cells. 2017 Jun 3
86 28597769 A systematic review of transition studies of pulmonary arterial hypertension specific medications. 2017 Apr-Jun 1
87 28751142 Design, synthesis and biological evaluation of dual acetylcholinesterase and phosphodiesterase 5A inhibitors in treatment for Alzheimer's disease. 2017 Sep 1 1
88 28798156 Phosphodiesterase 4 inhibitor and phosphodiesterase 5 inhibitor combination therapy has antifibrotic and anti-inflammatory effects in mdx mice with Duchenne muscular dystrophy. 2017 Dec 1
89 28860509 Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate. 2017 Aug 31 1
90 28956417 Potential risk of developing herpes simplex encephalitis in patients treated with sildenafil following primary exposure to genital herpes. 2017 Jul-Sep 2
91 28964803 Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets. 2017 Dec 1 4
92 29057299 Viagra releases the brakes on melanoma growth. 2017 5
93 29141888 Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk. 2017 Nov 15 1
94 29151951 Potential synergistic effect of phosphodiesterase inhibitors with chemotherapy in lung cancer. 2017 1
95 29245915 Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species. 2017 Nov 21 2
96 29256125 Phosphodiesterase Inhibitors (PDE Inhibitors) and Male Reproduction. 2017 1
97 25263347 LC-ESI-MS/MS analysis of phosphodiesterase-5 inhibitors and their analogues in foods and dietary supplements in Korea. 2016 1
98 26043796 Systematic Review of Phosphodiesterase-5 Inhibitor Use in Right Ventricular Failure Following Left Ventricular Assist Device Implantation. 2016 Feb 1
99 26108184 NF-κB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells: Inhibition by Sildenafil and Yonkenafil. 2016 May 5
100 26802314 Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats. 2016 May 1