| 51 |
31248114 | Biphasic Effect of Sildenafil on Energy Sensing is Mediated by Phosphodiesterases 2 and 3 in Adipocytes and Hepatocytes. | 2019 Jun 19 |
2 |
| 52 |
31311394 | Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts. | 2019 Aug 6 |
2 |
| 53 |
31350821 | The first-generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue. | 2019 Nov |
1 |
| 54 |
31409013 | Intervening with the Nitric Oxide Pathway to Alleviate Pulmonary Hypertension in Pulmonary Vein Stenosis. | 2019 Aug 12 |
1 |
| 55 |
31463257 | Investigating the effect of sildenafil on improving lung function and quality of life in the patients with severe asthma. | 2019 Jul |
1 |
| 56 |
29089445 | Novel imaging of the prostate reveals spontaneous gland contraction and excretory duct quiescence together with different drug effects. | 2018 Mar |
1 |
| 57 |
29467656 | Sublingual Administration of Sildenafil Oro-dispersible Film: New Profiles of Drug Tolerability and Pharmacokinetics for PDE5 Inhibitors. | 2018 |
1 |
| 58 |
29511676 | Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding. | 2018 |
2 |
| 59 |
29667180 | PDE5 inhibitors - pharmacology and clinical applications 20 years after sildenafil discovery. | 2018 Jul |
3 |
| 60 |
29694963 | Treatment of Macular Degeneration with Sildenafil: Results of a Two-Year Trial. | 2018 |
1 |
| 61 |
29735634 | Evaluation of Sildenafil and Tadalafil for Reversing Constriction of Fetal Arteries in a Human Placenta Perfusion Model. | 2018 Jul |
3 |
| 62 |
29901310 | [Current role of sildenafil in the management of erectile dysfunction]. | 2018 May |
1 |
| 63 |
30023062 | The effect of sildenafil on gastric motility and satiation in healthy controls. | 2018 Jul |
1 |
| 64 |
30148362 | Optimization of Chromeno[2,3- c]pyrrol-9(2 H)-ones as Highly Potent, Selective, and Orally Bioavailable PDE5 Inhibitors: Structure-Activity Relationship, X-ray Crystal Structure, and Pharmacodynamic Effect on Pulmonary Arterial Hypertension. | 2018 Sep 27 |
1 |
| 65 |
30292404 | Novel effect of sildenafil on hair growth. | 2018 Nov 2 |
2 |
| 66 |
30352768 | Role of neuronal nitric oxide synthase (nNOS) in Duchenne and Becker muscular dystrophies - Still a possible treatment modality? | 2018 Nov |
2 |
| 67 |
30381311 | TADAFER II: Tadalafil treatment for fetal growth restriction - a study protocol for a multicenter randomised controlled phase II trial. | 2018 Oct 30 |
2 |
| 68 |
30548639 | Tadalafil: 15 years' journey in male erectile dysfunction and beyond. | 2018 Dec 13 |
2 |
| 69 |
30705876 | Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems. | 2018 |
2 |
| 70 |
27101805 | A randomized clinical trial investigating treatment choice in Chinese men receiving sildenafil citrate and tadalafil for treating erectile dysfunction. | 2017 Jul-Aug |
2 |
| 71 |
27338710 | Adulteration of herbal sexual enhancers and slimmers: The wish for better sexual well-being and perfect body can be risky. | 2017 Oct |
2 |
| 72 |
27581752 | In silico design of novel hERG-neutral sildenafil-like PDE5 inhibitors. | 2017 Oct |
2 |
| 73 |
27979549 | Re: PDE5A Polymorphisms Influence on Sildenafil Treatment Success. | 2017 Jan |
1 |
| 74 |
27979766 | Nebulized solid lipid nanoparticles for the potential treatment of pulmonary hypertension via targeted delivery of phosphodiesterase-5-inhibitor. | 2017 Jan 30 |
2 |
| 75 |
28013386 | Potentiation of the NO-cGMP pathway and blood flow responses during dynamic exercise in healthy humans. | 2017 Feb |
1 |
| 76 |
28123846 | Phosphodiesterase-5 inhibition suppresses colonic inflammation-induced tumorigenesis via blocking the recruitment of MDSC. | 2017 |
2 |
| 77 |
28139291 | Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction: Pharmacology and Clinical Impact of the Sildenafil Citrate Orodispersible Tablet Formulation. | 2017 Feb |
2 |
| 78 |
28150511 | Investigation of PDE5/PDE6 and PDE5/PDE11 selective potent tadalafil-like PDE5 inhibitors using combination of molecular modeling approaches, molecular fingerprint-based virtual screening protocols and structure-based pharmacophore development. | 2017 Dec |
2 |
| 79 |
28211580 | Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux. | 2017 Jun |
2 |
| 80 |
28243607 | Treatment with Sildenafil and Donepezil Improves Angiogenesis in Experimentally Induced Critical Limb Ischemia. | 2017 |
2 |
| 81 |
28316997 | Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients. | 2017 |
2 |
| 82 |
28394532 | [Phosphodiesterase type 5 inhibitors in the treatment of erectile dysfunction: past, present and future]. | 2017 Apr |
1 |
| 83 |
28496549 | Phosphodiesterase-5 Inhibitors Improve Clinical Outcomes, Exercise Capacity and Pulmonary Hemodynamics in Patients With Heart Failure With Reduced Left Ventricular Ejection Fraction: A Meta-Analysis. | 2017 Jun |
2 |
| 84 |
28533270 | Classical activation of macrophages and vardenafil. | 2017 Jun 1 |
2 |
| 85 |
28587325 | Sildenafil suppresses the proliferation and enhances the apoptosis of hemangioma endothelial cells. | 2017 Jun |
3 |
| 86 |
28597769 | A systematic review of transition studies of pulmonary arterial hypertension specific medications. | 2017 Apr-Jun |
1 |
| 87 |
28751142 | Design, synthesis and biological evaluation of dual acetylcholinesterase and phosphodiesterase 5A inhibitors in treatment for Alzheimer's disease. | 2017 Sep 1 |
1 |
| 88 |
28798156 | Phosphodiesterase 4 inhibitor and phosphodiesterase 5 inhibitor combination therapy has antifibrotic and anti-inflammatory effects in mdx mice with Duchenne muscular dystrophy. | 2017 Dec |
1 |
| 89 |
28860509 | Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate. | 2017 Aug 31 |
1 |
| 90 |
28956417 | Potential risk of developing herpes simplex encephalitis in patients treated with sildenafil following primary exposure to genital herpes. | 2017 Jul-Sep |
2 |
| 91 |
28964803 | Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets. | 2017 Dec 1 |
4 |
| 92 |
29057299 | Viagra releases the brakes on melanoma growth. | 2017 |
5 |
| 93 |
29141888 | Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk. | 2017 Nov 15 |
1 |
| 94 |
29151951 | Potential synergistic effect of phosphodiesterase inhibitors with chemotherapy in lung cancer. | 2017 |
1 |
| 95 |
29245915 | Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species. | 2017 Nov 21 |
2 |
| 96 |
29256125 | Phosphodiesterase Inhibitors (PDE Inhibitors) and Male Reproduction. | 2017 |
1 |
| 97 |
25263347 | LC-ESI-MS/MS analysis of phosphodiesterase-5 inhibitors and their analogues in foods and dietary supplements in Korea. | 2016 |
1 |
| 98 |
26043796 | Systematic Review of Phosphodiesterase-5 Inhibitor Use in Right Ventricular Failure Following Left Ventricular Assist Device Implantation. | 2016 Feb |
1 |
| 99 |
26108184 | NF-κB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells: Inhibition by Sildenafil and Yonkenafil. | 2016 May |
5 |
| 100 |
26802314 | Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats. | 2016 May |
1 |