| 451 |
12625845 | Pharmacology of phosphodiesterase 5 inhibitors. | 2003 Feb |
1 |
| 452 |
12625847 | Cardiovascular safety of PDE5 inhibitors. | 2003 Feb |
2 |
| 453 |
12694895 | Effect of sildenafil (Viagra) on cerebral blood flow velocity: a pilot study. | 2003 Apr 1 |
4 |
| 454 |
12695418 | PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers. | 2003 May |
4 |
| 455 |
12761347 | [3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP. | 2003 Jun |
13 |
| 456 |
12825143 | [Sex, erectile dysfunction, and the heart: a growing problem]. | 2003 Jun |
2 |
| 457 |
12825147 | [New treatment options for erectile dysfunction. Pharmacologic and nonpharmacologic options]. | 2003 Jun |
2 |
| 458 |
12841917 | Sildenafil in erectile dysfunction: a critical review. | 2003 |
2 |
| 459 |
12842049 | Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity. | 2003 Jul |
1 |
| 460 |
12853767 | Up and down-regulation of phosphodiesterase-5 as related to tachyphylaxis and priapism. | 2003 Aug |
3 |
| 461 |
12934045 | Hypogonadism and erectile dysfunction: the role for testosterone therapy. | 2003 Aug |
2 |
| 462 |
12955149 | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules. | 2003 Sep 4 |
1 |
| 463 |
14551572 | Phosphodiesterase type 5 inhibitors: a biochemical and clinical correlation survey. | 2003 Oct |
1 |
| 464 |
14562136 | Effect of PDE5 inhibition combined with free oxygen radical scavenger therapy on erectile function in a diabetic animal model. | 2003 Oct |
1 |
| 465 |
14562139 | Single step isolation of sildenafil from commercially available Viagra tablets. | 2003 Oct |
1 |
| 466 |
14569380 | [Drug therapy of erectile dysfunction--the current status]. | 2003 Oct |
2 |
| 467 |
14609619 | Overview of phosphodiesterase 5 inhibition in erectile dysfunction. | 2003 Nov 6 |
1 |
| 468 |
14609621 | Sildenafil in patients with cardiovascular disease. | 2003 Nov 6 |
1 |
| 469 |
14618646 | Phosphodiesterase inhibitors for persistent pulmonary hypertension of the newborn: a review. | 2003 Dec |
2 |
| 470 |
14622499 | Molecular mechanisms and pharmacokinetics of phosphodiesterase-5 antagonists. | 2003 Dec |
1 |
| 471 |
14622500 | Erectile dysfunction in the cardiac patient. | 2003 Dec |
2 |
| 472 |
14652001 | Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF. | 2003 Dec 26 |
1 |
| 473 |
14687446 | Sildenafil citrate does not affect cardiac contractility in human or dog heart. | 2003 |
2 |
| 474 |
14693300 | Switching patients with erectile dysfunction from sildenafil citrate to tadalafil: results of a European multicenter, open-label study of patient preference. | 2003 Nov |
2 |
| 475 |
11815339 | Sildenafil induces retinal vasodilatation in healthy subjects. | 2002 Feb |
4 |
| 476 |
11896473 | Human PDE5A gene encodes three PDE5 isoforms from two alternate promoters. | 2002 Feb |
1 |
| 477 |
12002434 | Efficacy of vardenafil and sildenafil in facilitating penile erection in an animal model. | 2002 May-Jun |
2 |
| 478 |
12086542 | Neurologic, psychological, and aggressive disturbances with sildenafil. | 2002 Jul-Aug |
1 |
| 479 |
12145231 | Acute and prolonged effects of sildenafil on brachial artery flow-mediated dilatation in type 2 diabetes. | 2002 Aug |
4 |
| 480 |
12161769 | Tolerability and safety profile of sildenafil citrate (Viagra) in Latin American patient populations. | 2002 Aug |
1 |
| 481 |
12192104 | Effect of sildenafil on renin secretion in human subjects. | 2002 Sep |
1 |
| 482 |
12207947 | Viagra (sildenafil citrate) and ophthalmology. | 2002 Sep |
3 |
| 483 |
12209148 | Phosphodiesterase 5 inhibitors: current status and potential applications. | 2002 Sep |
2 |
| 484 |
12358156 | Erectile dysfunction: oral pharmacotherapy options. | 2002 Sep |
1 |
| 485 |
12414329 | Phosphodiesterase type 5 as a pharmacologic target in erectile dysfunction. | 2002 Sep |
4 |
| 486 |
12435622 | Erectile dysfunction: comparison of efficacy and side effects of the PDE-5 inhibitors sildenafil, vardenafil and tadalafil--review of the literature. | 2002 Oct 29 |
2 |
| 487 |
12437503 | A Rho-kinase inhibitor, soluble guanylate cyclase activator and nitric oxide-releasing PDE5 inhibitor: novel approaches to erectile dysfunction. | 2002 Nov |
2 |
| 488 |
12442206 | [Sildenafil for treatment of severe pulmonary hypertension and commencing right-heart failure]. | 2002 Nov |
2 |
| 489 |
12494279 | Phosphodiesterase type 5 inhibitors for the treatment of erectile dysfunction in patients with diabetes mellitus. | 2002 Dec |
2 |
| 490 |
12572636 | Therapeutic strategies for managing erectile dysfunction: a step-care approach. | 2002 Dec |
2 |
| 491 |
12836729 | PDE-5 inhibition and sexual response: pharmacological mechanisms and clinical outcomes. | 2002 |
2 |
| 492 |
15570464 | Use of cGMP PDE5 inhibitors in the treatment of neuropathy: a review of the patent literature. | 2002 May |
1 |
| 493 |
11162575 | Identification and regulation of human PDE5A gene promoter. | 2001 Jan 26 |
4 |
| 494 |
11162576 | Regulation of human PDE5A2 intronic promoter by cAMP and cGMP: identification of a critical Sp1-binding site. | 2001 Jan 26 |
4 |
| 495 |
11289565 | Phosphodiesterase isoenzymes as pharmacological targets in the treatment of male erectile dysfunction. | 2001 Feb |
1 |
| 496 |
11289569 | Sildenafil citrate, a selective phosphodiesterase type 5 inhibitor: urologic and cardiovascular implications. | 2001 Feb |
1 |
| 497 |
11306686 | Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A. | 2001 May |
1 |
| 498 |
11351772 | Phosphodiesterase 5 inhibition: effects on the coronary vasculature. | 2001 Apr |
1 |
| 499 |
11408180 | Synthesis and phosphodiesterase 5 inhibitory activity of novel phenyl ring modified sildenafil analogues. | 2001 Jun |
1 |
| 500 |
11557915 | The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men. | 2001 Sep |
2 |