Celecoxib

cytochrome c oxidase II, mitochondrial ; Rattus norvegicus







164 Article(s)
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1 34818572 Investigation of the anti-inflammatory and analgesic activities of promising pyrazole derivative. 2022 Jan 1 1
2 35121552 New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studies. 2022 Mar 2
3 31900051 Synthesis, characterization and anti-inflammatory activity evaluation of 1,2,4-triazole and its derivatives as a potential scaffold for the synthesis of drugs against prostaglandin-endoperoxide synthase. 2021 Feb 1
4 32795152 Arylidene analogues as selective COX-2 inhibitors: synthesis, characterization, in silico and in vitro studies. 2021 Nov 2
5 33421527 Emodin protects knee joint cartilage in rats through anti-matrix degradation pathway: An in vitro and in vivo study. 2021 Mar 15 1
6 33447032 Topical Nano-Vesicular Spanlastics of Celecoxib: Enhanced Anti-Inflammatory Effect and Down-Regulation of TNF-α, NF-кB and COX-2 in Complete Freund's Adjuvant-Induced Arthritis Model in Rats. 2021 2
7 33454504 Synthesis and biological evaluation of new nicotinate derivatives as potential anti-inflammatory agents targeting COX-2 enzyme. 2021 Feb 1
8 33577848 Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats. 2021 May 1 1
9 33679970 Celecoxib-Loaded Electrospun Fibrous Antiadhesion Membranes Reduce COX-2/PGE2 Induced Inflammation and Epidural Fibrosis in a Rat Failed Back Surgery Syndrome Model. 2021 1
10 33933169 The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation. 2021 May 1 1
11 34177398 Celecoxib Alleviates Radiation-Induced Brain Injury in Rats by Maintaining the Integrity of Blood-Brain Barrier. 2021 Apr-Jun 1
12 34382102 Montelukast potentiates the antiinflammatory effect of NSAIDs in the rat paw formalin model and simultaneously minimizes the risk of gastric damage. 2021 Sep 2
13 31490357 EP2 Receptor Blockade Attenuates COX-2 Upregulation During Intestinal Inflammation. 2020 Sep 2
14 31928220 Interaction of epidermal growth factor with COX-2 products and peroxisome proliferator-activated receptor-γ system in experimental rat Barrett's esophagus. 2020 Mar 1 1
15 32629287 Neuroprotective effect of novel celecoxib derivatives against spinal cord injury via attenuation of COX-2, oxidative stress, apoptosisand inflammation. 2020 Aug 2
16 33033527 Novel combination of celecoxib and metformin improves the antitumor effect by inhibiting the growth of Hepatocellular Carcinoma. 2020 1
17 33489027 Celecoxib inhibits acute edema and inflammatory biomarkers through peroxisome proliferator-activated receptor-γ in rats. 2020 Dec 2
18 30476507 Distinct influence of COX-1 and COX-2 on neuroinflammatory response and associated cognitive deficits during high altitude hypoxia. 2019 Mar 1 1
19 30782576 Ligand based design and synthesis of pyrazole based derivatives as selective COX-2 inhibitors. 2019 May 1
20 30870859 Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats. 2019 1
21 30904755 Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents. 2019 Jun 1 2
22 31231624 Celecoxib Protects Hyperoxia-Induced Lung Injury via NF-κB and AQP1. 2019 1
23 31306980 Inhibition of COX-2 alleviates lumbar spinal stenosis-induced chronic mechanical allodynia in rats. 2019 Oct 1
24 31539536 COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats. 2019 Dec 1 1
25 29519721 Low-dose NSAIDs reduce pain via macrophage targeted nanoemulsion delivery to neuroinflammation of the sciatic nerve in rat. 2018 May 15 1
26 29872269 Synthesis and evaluation of ortho-[18F] fluorocelecoxib for COX-2 cholangiocarcinoma imaging. 2018 2
27 29890922 Controlled release of celecoxib inhibits inflammation, bone cysts and osteophyte formation in a preclinical model of osteoarthritis. 2018 Nov 1
28 30143947 Preclinical Explorative Assessment of Celecoxib-Based Biocompatible Lipidic Nanocarriers for the Management of CFA-Induced Rheumatoid Arthritis in Wistar Rats. 2018 Oct 2
29 30242499 Preventative effect of celecoxib in dimethylbenz[a]anthracene-induced ovarian cancer in rats. 2018 Nov 1
30 28013183 Anti-inflammatory, analgesic and COX-2 inhibitory activity of novel thiadiazoles in irradiated rats. 2017 Jan 1
31 28024294 Celecoxib administration reduced mortality, mesenteric hypoperfusion, aortic dysfunction and multiple organ injury in septic rats. 2017 Feb 1
32 28054752 Opposite Modulatory Effects of Selective and Non-Selective Cyclooxygenase Inhibition on Cardiovascular and Autonomic Consequences of Cyclosporine in Female Rats. 2017 Jun 1
33 28284805 Novel 2-phenyl-4,5,6,7-tetrahydro[b]benzothiophene analogues as selective COX-2 inhibitors: Design, synthesis, anti-inflammatory evaluation, and molecular docking studies. 2017 Apr 15 1
34 28739304 Role of NADPHox/Rho-kinase signaling in the cyclosporine-NSAIDs interactions on blood pressure and baroreflexes in female rats. 2017 Sep 15 1
35 28742266 p-Coumaric acid, a dietary polyphenol ameliorates inflammation and curtails cartilage and bone erosion in the rheumatoid arthritis rat model. 2017 Sep 10 1
36 28979299 Physicochemical, Stress Degradation Evaluation and Pharmacokinetic Study of AZGH102, a New Synthesized COX2 Inhibitors after I.V. and Oral Administration in Male and Female Rats. 2017 Spring 1
37 27086898 Comparative pharmaceutical study on colon targeted micro-particles of celecoxib: in-vitro-in-vivo evaluation. 2016 Nov 1
38 25687638 Celecoxib Combined with Diacerein Effectively Alleviates Osteoarthritis in Rats via Regulating JNK and p38MAPK Signaling Pathways. 2015 Aug 1
39 25860026 Colonic delivery of celecoxib is a potential pharmaceutical strategy for repositioning the selective COX-2 inhibitor as an anti-colitic agent. 2015 Oct 1
40 26441478 Histopathology and oxidative stress analysis of concomitant misoprostol and celecoxib administration. 2015 Jul 1
41 24064301 Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. 2014 Jan 1
42 24135073 NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same? 2014 Jan 1
43 24446128 Upregulation of androgen-responsive genes and transforming growth factor-β1 cascade genes in a rat model of non-bacterial prostatic inflammation. 2014 Apr 1
44 24622834 Involvement of cyclooxygenase-1 and cyclooxygenase-2 activity in the therapeutic effect of ghrelin in the course of ethanol-induced gastric ulcers in rats. 2014 Feb 1
45 24721996 Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN. 2014 Mar 30 1
46 24811609 Celecoxib modulates nitric oxide and reactive oxygen species in kidney ischemia/reperfusion injury and rat aorta model of hypoxia/reoxygenation. 2014 Jul 2
47 24878170 Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition. 2014 Oct 1
48 24905509 Pharmacological characterization of carrageenan induced heat muscle hyperalgesia in rats using non-selective, preferential and selective COX-2 inhibitors. 2014 Jun 1
49 24932515 Chrysin alleviates testicular dysfunction in adjuvant arthritic rats via suppression of inflammation and apoptosis: comparison with celecoxib. 2014 Sep 1 1
50 25140201 The effects of cyclooxygenase inhibitors on the gastric emptying and small intestine transit in the male rats following traumatic brain injury. 2014 Jun 2