nimesulide

cytochrome c oxidase II, mitochondrial ; Rattus norvegicus







58 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34052431 Chronic cyclooxygenase-2 inhibition prevents the worsening of hypertension and endothelial dysfunction induced by ouabain in resistance arteries of spontaneously hypertensive rats. 2021 Aug 1
2 32632112 Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide. 2020 Jul 6 1
3 27188793 Adenosine signalling mediates the anti-inflammatory effects of the COX-2 inhibitor nimesulide. 2016 Jul 15 1
4 24675150 The role of endothelium-derived hyperpolarizing factor and cyclooxygenase pathways in the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in chronic sarpogrelate treated rats. 2014 May 15 1
5 24948067 Protective effect of nimesulide against hepatic ischemia/reperfusion injury in rats: effects on oxidant/antioxidants, DNA mutation and COX-1/COX-2 levels. 2014 Aug 1
6 23117109 Signal transduction and modulating pathways in tryptamine-evoked vasopressor responses of the rat isolated perfused mesenteric bed. 2013 Jan 1
7 23179355 MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. 2013 Mar 1
8 23587942 COX-2 expression in stromal fibroblasts self-limits their numbers in lymph node inflammatory responses. 2013 Oct 3
9 21866634 [The effect of nimesulide on learning and memory function after serve traumatic brain injury in rats]. 2011 Jul 1
10 20018235 Evaluation of guggulipid and nimesulide on production of inflammatory mediators and GFAP expression in LPS stimulated rat astrocytoma, cell line (C6). 2010 Feb 17 1
11 20043093 Enhancement of tongue carcinogenesis in Hras128 transgenic rats treated with 4-nitroquinoline 1-oxide. 2010 Feb 2
12 20091905 Addition of nimesulide to small intestinal submucosa biomaterial inhibits postsurgical adhesiogenesis in rats. 2010 Apr 2
13 29913996 The attenuation of pain behaviour and serum interleukin-6 concentration by nimesulide in a rat model of neuropathic pain. 2010 Oct 1 1
14 19524064 Role of cyclooxygenase in vasodilation of retinal blood vessels induced by bradykinin in Brown Norway rats. 2009 Aug-Sep 1
15 18079364 Down-regulation of hepatic cytochrome P450 enzymes in rats with trinitrobenzene sulfonic acid-induced colitis. 2008 Mar 1
16 19099228 Four-week administration of nimesulide, a cyclooxygenase-2 inhibitor, improves endothelial dysfunction in the hindlimb vasculature of streptozotocin-induced diabetic rats. 2008 Dec 2
17 17176264 Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats. 2007 Feb 2
18 17245358 Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. 2007 Mar 1
19 17258197 Interaction between cyclooxygenase (COX)-1- and COX-2-products modulates COX-2 expression in the late phase of acute inflammation. 2007 Mar 22 3
20 17675820 [Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide]. 2007 Aug 4
21 17940709 COX-2 inhibitor nimesulide protects rat heart against oxidative stress by improving endothelial function and enhancing NO production. 2007 Oct 25 1
22 18080691 [The effect of nonsteroidal anti-inflammatory drugs on oxidative/antioxidative balance]. 2007 Sep 1
23 16536784 Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymes. 2006 Apr 1
24 16622181 Cyclooxygenase-2 inhibition normalizes arterial blood pressure in CYP1A1-REN2 transgenic rats with inducible ANG II-dependent malignant hypertension. 2006 Sep 1
25 16814279 Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms. 2006 Aug 14 1
26 15564788 Are prostanoids related to positive inotropism by UTP and ATP? 2005 Mar 1
27 15626595 In vivo endothelial interaction between ACE and COX inhibitors. 2005 Feb 1
28 16120189 Involvement of endothelial cyclo-oxygenase metabolites in noradrenaline-induced contraction of rat coronary artery. 2005 Aug 2
29 15086448 TNF-alpha hyperpolarizes membrane potential and potentiates the response to nicotinic receptor stimulation in cultured rat myenteric neurones. 2004 May 1
30 12507282 A COX-2 inhibitor, nimesulide, inhibits chemically-induced rat tongue carcinogenesis through suppression of cell proliferation activity and COX-2 and iNOS expression. 2003 Jan 4
31 12643859 Differential salutary effects of nonselective and selective COX-2 inhibitors in postoperative ileus in rats. 2003 Feb 1
32 12969784 Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide. 2003 Sep 25 1
33 14506907 Central components of the analgesic/antihyperalgesic effect of nimesulide: studies in animal models of pain and hyperalgesia. 2003 1
34 14506908 High-throughput proteomics and protein biomarker discovery in an experimental model of inflammatory hyperalgesia: effects of nimesulide. 2003 2
35 14518559 Effect of nimesulide on acetic acid- and leukotriene-induced inflammatory bowel disease in rats. 2003 Jul 1
36 14566678 Expression of cyclooxygenase-2 in primary superficial bladder cancer tissue may predict risk of its recurrence after complete transurethral resection. 2003 Jul 1
37 22900315 Nimesulide affects antioxidant status during acute lung inflammation in rats. 2003 Aug 1
38 11872629 Increased expression of cyclooxygenase-2 protein during rat hepatocarcinogenesis caused by a choline-deficient, L-amino acid-defined diet and chemopreventive efficacy of a specific inhibitor, nimesulide. 2002 Feb 2
39 12086401 COX-2 and prostanoid receptors: good targets for chemoprevention. 2002 2
40 12189188 Inhibitory effects of mofezolac, a cyclooxygenase-1 selective inhibitor, on intestinal carcinogenesis. 2002 Sep 1
41 12410334 Inhibition of cyclooxygenase 2 by nimesulide improves cognitive outcome more than motor outcome following diffuse traumatic brain injury in rats. 2002 Nov 2
42 11263679 A reduction of tumor necrosis factor-alpha in paw exudate of lipopolysaccharide treated rats by nimesulide. 2001 Feb 23 1
43 11264253 Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve. 2001 Apr 1
44 11473974 Prevention of postoperative adhesion formation in rat uterine horn model by nimesulide: a selective COX-2 inhibitor. 2001 Aug 1
45 11990080 Effect of cyclooxygenase and NO synthase inhibitors on antinociceptive action of acetaminophen. 2001 Jul-Aug 1
46 10783320 The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats. 2000 May 3
47 10961715 In vivo selectivity of nonsteroidal antiinflammatory drugs and gastrointestinal ulcers in rats. 2000 Jul 1
48 10961716 Interaction between NSAIDs and steroid in rat stomach: safety of nimesulide as a preferential COX-2 inhibitor in the stomach. 2000 Jul 2
49 11216473 COX-2 and iNOS, good targets for chemoprevention of colon cancer. 2000 1
50 10072704 Anti-inflammatory activity and pharmacokinetic profile of a new parenteral formulation of nimesulide. 1999 Feb 1