Valproic Acid

histone deacetylase 9 ; Homo sapiens







107 Article(s)
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1 35433850 The Histone Deacetylase 9 Stroke-Risk Variant Promotes Apoptosis and Inflammation in a Human iPSC-Derived Smooth Muscle Cells Model. 2022 1
2 35565292 HDAC Inhibition with Valproate Improves Direct Cytotoxicity of Monocytes against Mesothelioma Tumor Cells. 2022 Apr 26 1
3 33031880 Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activity. 2021 Jan 10 1
4 33369712 Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain: involvement of histone deacetylase inhibition. 2021 Feb 1
5 34374891 Effect of valproic acid on miRNAs affecting histone deacetylase in a model of anaplastic thyroid cancer. 2021 Aug 2
6 34935488 HDAC9 in the Injury of Vascular Endothelial Cell Mediated by P38 MAPK Pathway. 2021 Dec 2
7 34944565 Synergistic Anticancer Effect of Glycolysis and Histone Deacetylases Inhibitors in a Glioblastoma Model. 2021 Nov 23 3
8 31898801 Valproic Acid Decreases Endothelial Colony Forming Cells Differentiation and Induces Endothelial-to-Mesenchymal Transition-like Process. 2020 Apr 5
9 32378621 Effect of epigenetic modulation on cancer sphere. 2020 2
10 32591993 HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line. 2020 Oct 1
11 30183517 Palbociclib augments Neratinib killing of tumor cells that is further enhanced by HDAC inhibition. 2019 1
12 31010254 Influence of the HDAC Inhibitor Valproic Acid on the Growth and Proliferation of Temsirolimus-Resistant Prostate Cancer Cells In Vitro. 2019 Apr 19 5
13 28550492 microRNA-889 is downregulated by histone deacetylase inhibitors and confers resistance to natural killer cytotoxicity in hepatocellular carcinoma cells. 2018 Apr 2
14 28967098 Epigenetic regulation of melatonin receptors in neuropsychiatric disorders. 2018 Aug 2
15 29135083 Comparison of the anticancer properties of a novel valproic acid prodrug to leading histone deacetylase inhibitors. 2018 Apr 5
16 29247141 Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack. 2018 Jan 2
17 30050079 Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells. 2018 Jul 26 1
18 30107147 CCR7 preservation via histone deacetylase inhibition promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells. 2018 Oct 1 2
19 28445158 The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo. 2017 Jun 6 2
20 28542253 Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma. 2017 1
21 26517778 Histone deactylase gene expression profiles are associated with outcomes in blunt trauma patients. 2016 Jan 3
22 26822725 Quantitative Analysis of Global Proteome and Lysine Acetylome Reveal the Differential Impacts of VPA and SAHA on HL60 Cells. 2016 Jan 29 3
23 26827693 The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies. 2016 Feb 1
24 26980768 Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance. 2016 May 15 1
25 27038166 Antiepileptic drugs with histone deacetylase inhibition activity and prostate cancer risk: a population-based case-control study. 2016 May 1
26 27411759 Anti-fibrotic effects of valproic acid: role of HDAC inhibition and associated mechanisms. 2016 Aug 2
27 27470189 Histone deacetylase inhibitors stimulate the susceptibility of A549 cells to a plasma-activated medium treatment. 2016 Sep 15 2
28 27884140 Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial. 2016 Nov 25 2
29 25012937 HDAC inhibition through valproic acid modulates the methylation profiles in human embryonic kidney cells. 2015 3
30 25336333 Results of phase 2 randomized study of low-dose decitabine with or without valproic acid in patients with myelodysplastic syndrome and acute myelogenous leukemia. 2015 Feb 15 1
31 25656984 Safety of valproic acid in patients with chronic obstructive pulmonary disease: a population-based cohort study. 2015 Mar 3
32 25950486 Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells. 2015 May 7 4
33 25960665 Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer. 2015 2
34 26108793 Nucleolar Translocation of Histone Deacetylase 2 Is Involved in Regulation of Transcriptional Silencing in the Cat Germinal Vesicle. 2015 Aug 2
35 26185616 Cellular prostatic acid phosphatase (cPAcP) serves as a useful biomarker of histone deacetylase (HDAC) inhibitors in prostate cancer cell growth suppression. 2015 1
36 26318673 Histone deacetylase inhibitors relieve morphine resistance in neuropathic pain after peripheral nerve injury. 2015 Aug 2
37 26482599 Antiepileptic drug use improves overall survival in breast cancer patients with brain metastases in the setting of whole brain radiotherapy. 2015 Nov 4
38 26735433 Induction of autophagy by valproic acid enhanced lymphoma cell chemosensitivity through HDAC-independent and IP3-mediated PRKAA activation. 2015 5
39 24511897 Suppression of adipogenesis by valproic acid through repression of USF1-activated fatty acid synthesis in adipocytes. 2014 May 1 4
40 24890032 Is sodium valproate, an HDAC inhibitor, associated with reduced risk of stroke and myocardial infarction? A nested case-control study. 2014 Jul 1
41 25108044 The histone deacetylase (HDAC) inhibitor valproic acid reduces ethanol consumption and ethanol-conditioned place preference in rats. 2014 Oct 2 3
42 25446377 Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting BNIP3, autophagy, and mitochondria with low doses of valproic acid and vincristine. 2014 Dec 4
43 23010695 Enantioselective apoptosis induction in histiocytic lymphoma cells and acute promyelocytic leukemia cells. 2013 Feb 4
44 23097134 Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition. 2013 Apr 2
45 23292124 Synergistic effects of histone deacetylase inhibitor in combination with mTOR inhibitor in the treatment of prostate carcinoma. 2013 Feb 2
46 23448466 Potential roles of HDAC inhibitors in mitigating ischemia-induced brain damage and facilitating endogenous regeneration and recovery. 2013 1
47 23647222 The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. 2013 Jul 1
48 23836985 Inhibition of leukemic cells by valproic acid, an HDAC inhibitor, in xenograft tumors. 2013 1
49 24006305 HDAC inhibition suppresses bladder cancer cell adhesion to collagen under flow conditions. 2013 Nov 1 4
50 22473339 Low dosed interferon alpha augments the anti-tumor potential of histone deacetylase inhibition on prostate cancer cell growth and invasion. 2012 Dec 1 4