Betaine

betaine--homocysteine S-methyltransferase ; Homo sapiens







34 Article(s)
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1 33975330 The BHMT-betaine methylation pathway epigenetically modulates oligodendrocyte maturation. 2021 1
2 32096676 Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis. 2020 Aug 1
3 32939549 Associations between Plasma Choline Metabolites and Genetic Polymorphisms in One-Carbon Metabolism in Postmenopausal Women: The Women's Health Initiative Observational Study. 2020 Nov 19 1
4 30746538 Alleviation of paraquat-induced oxidative lung injury by betaine via regulation of sulfur-containing amino acid metabolism despite the lack of betaine-homocysteine methyltransferase (BHMT) in the lung. 2019 Feb 20 2
5 28468239 Choline, Other Methyl-Donors and Epigenetics. 2017 Apr 29 1
6 26592251 Downregulation of betaine homocysteine methyltransferase (BHMT) in hepatocellular carcinoma associates with poor prognosis. 2016 May 2
7 25466894 Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts. 2015 Mar 3
8 25931143 Role of defective methylation reactions in ethanol-induced dysregulation of intestinal barrier integrity. 2015 Jul 1 1
9 26182429 High homocysteine induces betaine depletion. 2015 Apr 28 1
10 26213999 Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes. 2015 2
11 26527363 Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets. 2015 Nov 25 1
12 24795654 The betaine/GABA transporter and betaine: roles in brain, kidney, and liver. 2014 3
13 24895213 Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase. 2014 Oct 2
14 23378610 Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes. 2013 Jun 1
15 23727536 The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase. 2013 Jul 2
16 22357209 Corticoadrenal activity in rat regulates betaine-homocysteine S-methyltransferase expression with opposite effects in liver and kidney. 2012 Mar 2
17 22847001 Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development. 2012 Sep 21 2
18 23014492 Homocysteinemia in mice with genetic betaine homocysteine S-methyltransferase deficiency is independent of dietary folate intake. 2012 Nov 1
19 21878621 Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. 2011 Oct 21 1
20 19534555 Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase. 2009 Jun 25 2
21 18230605 Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase. 2008 Apr 4 2
22 16038618 Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro. 2005 Dec 15 3
23 15006639 Betaine analogues alter homocysteine metabolism in rats. 2004 May 2
24 15122900 Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis. 2004 May 11 2
25 12818402 Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease. 2003 Apr 1
26 11883905 Random mutagenesis of the zinc-binding motif of betaine-homocysteine methyltransferase reveals that Gly 214 is essential. 2002 Mar 1 2
27 12220488 Betaine-homocysteine methyltransferase: zinc in a distorted barrel. 2002 Sep 2
28 11380830 Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. 2001 Jun 4
29 10987370 Association of betaine-homocysteine S-methyltransferase with microtubules. 2000 Jul 1
30 11087663 Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes. 2000 Nov 15 1
31 10075673 Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene. 1999 Mar 19 2
32 10529246 Recombinant human liver betaine-homocysteine S-methyltransferase: identification of three cysteine residues critical for zinc binding. 1999 Oct 19 2
33 8798461 Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase. 1996 Sep 13 1
34 8836329 Betaine, ethanol, and the liver: a review. 1996 Jul-Aug 1