| 1 |
35235777 | Creatine transport and creatine kinase activity is required for CD8+ T cell immunity. | 2022 Mar 1 |
1 |
| 2 |
31541182 | DAPK1 (death associated protein kinase 1) mediates mTORC1 activation and antiviral activities in CD8+ T cells. | 2021 Jan |
1 |
| 3 |
33512760 | Comprehensive analysis of the immunomodulatory effects of rapamycin on human T cells in graft-versus-host disease prophylaxis. | 2021 Aug |
2 |
| 4 |
33883257 | Amino acids and RagD potentiate mTORC1 activation in CD8+ T cells to confer antitumor immunity. | 2021 Apr |
1 |
| 5 |
33013932 | Regulation of RLR-Mediated Antiviral Responses of Human Dendritic Cells by mTOR. | 2020 |
1 |
| 6 |
30710341 | mTOR Signaling pathway as a master regulator of memory CD8+ T-cells, Th17, and NK cells development and their functional properties. | 2019 Aug |
1 |
| 7 |
30867239 | 4-1BB Regulates Effector CD8 T Cell Accumulation in the Lung Tissue through a TRAF1-, mTOR-, and Antigen-Dependent Mechanism to Enhance Tissue-Resident Memory T Cell Formation during Respiratory Influenza Infection. | 2019 Apr 15 |
1 |
| 8 |
31191530 | Comprehensive Characterization of a Next-Generation Antiviral T-Cell Product and Feasibility for Application in Immunosuppressed Transplant Patients. | 2019 |
1 |
| 9 |
31408438 | Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease. | 2019 Aug 13 |
1 |
| 10 |
29551338 | Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial. | 2018 Mar 24 |
2 |
| 11 |
30228949 | Clinically-Relevant Rapamycin Treatment Regimens Enhance CD8+ Effector Memory T Cell Function In The Skin and Allow their Infiltration into Cutaneous Squamous Cell Carcinoma. | 2018 |
1 |
| 12 |
30619313 | Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression. | 2018 |
1 |
| 13 |
29445370 | Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/- Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice. | 2017 |
1 |
| 14 |
26437614 | Respiratory syncytial virus induces phosphorylation of mTOR at ser2448 in CD8 T cells from nasal washes of infected infants. | 2016 Feb |
1 |
| 15 |
26680373 | Eomesodermin(lo) CTLA4(hi) Alloreactive CD8+ Memory T Cells Are Associated With Prolonged Renal Transplant Survival Induced by Regulatory Dendritic Cell Infusion in CTLA4 Immunoglobulin-Treated Nonhuman Primates. | 2016 Jan |
1 |
| 16 |
26921303 | Suppressor Properties of Human CD8(+)CD28(-) T Cells in Mixed Leukocyte Reaction are not Affected by CsA and RAPA. | 2016 Oct |
3 |
| 17 |
27466155 | Rapamycin increases RSV RNA levels and survival of RSV-infected dendritic cell depending on T cell contact. | 2016 Oct |
1 |
| 18 |
25833958 | Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg. | 2015 May 7 |
1 |
| 19 |
25989700 | Rapamycin ameliorates the CTLA4-Ig-mediated defect in CD8(+) T cell immunity during gammaherpesvirus infection. | 2015 Oct |
4 |
| 20 |
26037126 | Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria. | 2015 Jun 2 |
1 |
| 21 |
26122844 | Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication. | 2015 Aug 15 |
1 |
| 22 |
24107844 | Rapamycin induces ILT3(high)ILT4(high) dendritic cells promoting a new immunoregulatory pathway. | 2014 Apr |
2 |
| 23 |
24683191 | Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus. | 2014 May 1 |
1 |
| 24 |
24913978 | Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections. | 2014 Jul 15 |
1 |
| 25 |
25070853 | Cutting edge: generation of effector cells that localize to mucosal tissues and form resident memory CD8 T cells is controlled by mTOR. | 2014 Sep 1 |
2 |
| 26 |
23799424 | Expansion of memory-type CD8+ T cells correlates with the failure of early immunosuppression withdrawal after cadaver liver transplantation using high-dose ATG induction and rapamycin. | 2013 Aug 15 |
1 |
| 27 |
24123683 | Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. | 2013 Nov 15 |
1 |
| 28 |
22186790 | Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines. | 2012 Apr |
1 |
| 29 |
22300641 | Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus. | 2012 Jun |
1 |
| 30 |
22379028 | Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity. | 2012 Apr 1 |
2 |
| 31 |
21439133 | Rapamycin generates graft-homing murine suppressor CD8(+) T cells that confer donor-specific graft protection. | 2011 |
3 |
| 32 |
21511183 | A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity. | 2011 Apr 22 |
1 |
| 33 |
21611151 | Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells. | 2011 |
1 |
| 34 |
20933441 | Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. | 2010 Oct 29 |
1 |
| 35 |
19424019 | Acute liver transplant rejection upon immunosuppression withdrawal in a tolerance induction trial: potential role of IFN-gamma-secreting CD8+ T cells. | 2009 May 15 |
1 |
| 36 |
16461044 | Comparison between sirolimus- and paclitaxel-eluting stent in T-cell subsets redistribution. | 2006 Feb 15 |
1 |
| 37 |
16477233 | Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells. | 2006 Feb 15 |
1 |
| 38 |
15585311 | Altered trafficking of CD8+ memory T cells after implantation of rapamycin-eluting stents in patients with coronary artery disease. | 2005 Jan 15 |
3 |
| 39 |
14573608 | Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity. | 2004 Jan 9 |
1 |
| 40 |
11207273 | Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes. | 2001 Mar 1 |
4 |
| 41 |
7586731 | Direct inhibition of human CD8+ lymphocyte activation by cyclosporine A and Rapamune-Sirolimus. | 1995 Dec |
3 |
| 42 |
8286755 | Rapamycin, a potent inhibitor of T-cell function, prevents graft rejection in murine recipients of allogeneic T-cell-depleted donor marrow. | 1994 Jan 15 |
1 |