Threonine

microtubule associated protein tau ; Homo sapiens







170 Article(s)
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Pub. Year
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51 28353223 Multiplexing Biomarker Methods, Proteomics and Considerations for Alzheimer's Disease. 2017 1
52 28521765 Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice. 2017 May 18 1
53 28866979 Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome. 2017 Sep 4 1
54 25465240 Olfactory Deprivation Hastens Alzheimer-Like Pathologies in a Human Tau-Overexpressed Mouse Model via Activation of cdk5. 2016 Jan 2
55 26253588 Mapping CSF biomarker profiles onto NIA-AA guidelines for Alzheimer's disease. 2016 Oct 1
56 26836182 Cerebrospinal Fluid Markers of Alzheimer's Disease Pathology and Microglial Activation are Associated with Altered White Matter Microstructure in Asymptomatic Adults at Risk for Alzheimer's Disease. 2016 1
57 26890756 The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer's Disease. 2016 1
58 27073990 DYRK1A inhibition as potential treatment for Alzheimer's disease. 2016 Apr 1
59 27276722 [Cerebrospinal fluid biomarkers of Alzheimer's disease in current clinical practice]. 2016 Apr 20 2
60 27280380 Gramine Derivatives Targeting Ca(2+) Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases. 2016 Jul 14 1
61 27296778 Alzheimer's disease cerebrospinal fluid biomarkers predict cognitive decline in lewy body dementia. 2016 Aug 1
62 25467137 Configuration-specific immunotherapy targeting cis pThr231-Pro232 tau for Alzheimer disease. 2015 Jan 15 3
63 25659857 Influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease. 2015 Mar 2
64 25707998 Different cerebrospinal fluid levels of Alzheimer-type biomarker Aβ42 between general paresis and asymptomatic neurosyphilis. 2015 May 1
65 26366630 Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease. 2015 Nov 1
66 26402072 Matrix Metalloproteinases in Alzheimer's Disease and Concurrent Cerebral Microbleeds. 2015 2
67 23969178 Blood pressure decrease correlates with tau pathology and memory decline in hypertensive elderly. 2014 Jan 2
68 24033439 Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. 2014 Feb 1
69 24378367 The role of clusterin in amyloid-β-associated neurodegeneration. 2014 Feb 1
70 24444746 O-GlcNAc modification of tau directly inhibits its aggregation without perturbing the conformational properties of tau monomers. 2014 Apr 17 1
71 24492862 Phosphorylated tau as a candidate biomarker for amyotrophic lateral sclerosis. 2014 Apr 1
72 24548642 Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer's disease in multiplex immunoassay panels of cerebrospinal fluid. 2014 May 1 1
73 22710920 Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration. 2013 1
74 23362255 Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. 2013 Mar 15 2
75 23430246 β2 adrenergic receptor, protein kinase A (PKA) and c-Jun N-terminal kinase (JNK) signaling pathways mediate tau pathology in Alzheimer disease models. 2013 Apr 12 3
76 21741127 Serial CSF sampling in Alzheimer's disease: specific versus non-specific markers. 2012 Aug 1
77 21945393 Wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models. 2012 Jan 2
78 22057275 Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. 2012 Feb 3 1
79 22153704 [Multicenter study on lumbar puncture indication, clinical practice and feasibility]. 2012 Jan 2
80 22332192 Cerebrospinal fluid Aβ and tau level fluctuation in an older clinical cohort. 2012 Feb 2
81 22334661 Synaptic released zinc promotes tau hyperphosphorylation by inhibition of protein phosphatase 2A (PP2A). 2012 Mar 30 2
82 22367557 Roles of AMP-activated protein kinase in Alzheimer's disease. 2012 Mar 1
83 20706749 Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody. 2011 Mar 1
84 21056617 Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. 2011 Jan 2
85 21220682 Cerebrospinal fluid profiles and prospective course and outcome in patients with amnestic mild cognitive impairment. 2011 Jan 1
86 21573099 β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites. 2011 May 6 1
87 21671254 Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes. 2011 Sep 1
88 18692273 Whole-brain atrophy rate and CSF biomarker levels in MCI and AD: a longitudinal study. 2010 May 2
89 19853650 Total and phosphorylated tau protein as biological markers of Alzheimer's disease. 2010 Jan 1
90 20110615 Tau phosphorylated at tyrosine 394 is found in Alzheimer's disease tangles and can be a product of the Abl-related kinase, Arg. 2010 1
91 20186703 Nerve growth factor as a paradigm of neurotrophins related to Alzheimer's disease. 2010 Apr 1
92 20472896 Oligemic hypoperfusion differentially affects tau and amyloid-{beta}. 2010 Jul 1
93 20609109 Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy. 2010 Oct 1
94 20862329 SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease. 2010 Sep 16 1
95 21084733 Cerebrospinal fluid markers for Alzheimer's disease over the lifespan: effects of age and the APOEε4 genotype. 2010 1
96 19046355 Tau phosphorylation at threonine-175 leads to fibril formation and enhanced cell death: implications for amyotrophic lateral sclerosis with cognitive impairment. 2009 Feb 1
97 19146641 CSF biomarker profile and diagnostic value in vascular dementia. 2009 Feb 1
98 19307538 CSF biomarkers in relationship to cognitive profiles in Alzheimer disease. 2009 Mar 24 2
99 19524111 Improved discrimination of autopsy-confirmed Alzheimer's disease (AD) from non-AD dementias using CSF P-tau(181P). 2009 Sep 1
100 19623258 The excitotoxin quinolinic acid induces tau phosphorylation in human neurons. 2009 Jul 22 1