Proline

microtubule associated protein tau ; Homo sapiens







80 Article(s)
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51 10090741 Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments. 1999 Mar 23 3
52 10218629 Tau pathology in a family with dementia and a P301L mutation in tau. 1999 Apr 1
53 10360762 From genotype to phenotype: a clinical pathological, and biochemical investigation of frontotemporal dementia and parkinsonism (FTDP-17) caused by the P301L tau mutation. 1999 Jun 1
54 10413323 Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain. 1999 May 1
55 10553987 FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation. 1999 Nov 1
56 8990130 Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain. 1997 Jan 1
57 9202310 Reactivating kinase/p38 phosphorylates tau protein in vitro. 1997 Jul 2
58 8674537 Calcium/calmodulin-dependent protein kinase II phosphorylates tau at Ser-262 but only partially inhibits its binding to microtubules. 1996 Jun 3 2
59 8725894 Glycogen synthase kinase 3 alpha and 3 beta do not colocalize with neurofibrillary tangles. 1996 May-Jun 1
60 7477934 Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease. 1995 Sep 4
61 7531159 Rapid Alzheimer-like phosphorylation of tau by the synergistic actions of non-proline-dependent protein kinases and GSK-3. 1995 Jan 30 2
62 7566342 Molecular dissection of the paired helical filament. 1995 May-Jun 1
63 7566347 Alzheimer neurofibrillary lesions: molecular nature and potential roles of different components. 1995 May-Jun 1
64 7763334 Molecular dissection of the neurofibrillary lesions of Alzheimer's disease. 1995 Mar 1
65 7822317 Proline-directed and non-proline-directed phosphorylation of PHF-tau. 1995 Jan 13 4
66 8544900 Isolation of a phosphorylated soluble tau fraction from Alzheimer's disease brain. 1995 Jul-Aug 1
67 7517023 Dephosphorylation of tau protein from Alzheimer's disease patients. 1994 Jan 3 1
68 7854037 Microtubule-associated protein MAP1B showing a fetal phosphorylation pattern is present in sites of neurofibrillary degeneration in brains of Alzheimer's disease patients. 1994 Oct 1
69 8129042 Extracellular signal regulated kinases. Localization of protein and mRNA in the human hippocampal formation in Alzheimer's disease. 1994 Mar 3
70 7507619 Tau protein and the neurofibrillary pathology of Alzheimer's disease. 1993 Nov 1
71 7689658 p44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippocampal neurons. 1993 Jul 1 1
72 8226879 Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments. 1993 Nov 5 2
73 8393323 Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding. 1993 Jul 1
74 8512563 Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease. 1993 Jun 15 1
75 1334849 Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau. 1992 Dec 21 1
76 1376245 Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state. 1992 Jun 5
77 1376918 Phosphorylation-dependent epitopes of neurofilament antibodies on tau protein and relationship with Alzheimer tau. 1992 Jun 15 1
78 1563356 The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. 1992 Apr 1
79 1644173 The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs. 1992 Jul 28 3
80 2501795 Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease. 1989 Jul 1