Imatinib Mesylate

platelet derived growth factor receptor, alpha polypeptide ; Mus musculus







34 Article(s)
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1 35122213 Compartmentalized Actions of the Plasminogen Activator Inhibitors, PAI-1 and Nsp, in Ischemic Stroke. 2022 Feb 4 1
2 35528149 Imatinib Mesylate Reduces Neurotrophic Factors and pERK and pAKT Expression in Urinary Bladder of Female Mice With Cyclophosphamide-Induced Cystitis. 2022 1
3 34027663 Chrysin Stimulates Subcutaneous Fat Thermogenesis in Mice by Regulating PDGFRα and MicroRNA Expressions. 2021 Jun 2 1
4 34247157 Gleevec and Rapamycin Synergistically Reduce Cell Viability and Inhibit Proliferation and Angiogenic Function of Mouse Bone Marrow-Derived Endothelial Progenitor Cells. 2021 1
5 32590338 Tyrosine kinase inhibitor therapy and metabolic remodelling in papillary thyroid cancer. 2020 Sep 1
6 32597702 Reduced Platelet miR-223 Induction in Kawasaki Disease Leads to Severe Coronary Artery Pathology Through a miR-223/PDGFRβ Vascular Smooth Muscle Cell Axis. 2020 Sep 11 1
7 32944951 A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin. 2020 Dec 1
8 31428517 Immune microenvironment profiling of gastrointestinal stromal tumors (GIST) shows gene expression patterns associated to immune checkpoint inhibitors response. 2019 1
9 29570794 Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis. 2018 Jun 1
10 29915281 Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas. 2018 Jun 19 1
11 30007969 Imatinib Ameliorated Retinal Neovascularization by Suppressing PDGFR-α and PDGFR-β. 2018 3
12 28139720 Inhibition of PDGFR signaling prevents muscular fatty infiltration after rotator cuff tear in mice. 2017 Jan 31 2
13 25865047 Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. 2015 Aug 2
14 26500491 Imatinib treatment reduces brain injury in a murine model of traumatic brain injury. 2015 1
15 24407160 Identification of Ponatinib as a potent inhibitor of growth, migration, and activation of neoplastic eosinophils carrying FIP1L1-PDGFRA. 2014 Apr 1
16 24486648 Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis. 2014 May 2
17 24599309 Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models. 2014 1
18 23041331 Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit. 2013 Jan 1
19 24009732 The conformational control inhibitor of tyrosine kinases DCC-2036 is effective for imatinib-resistant cells expressing T674I FIP1L1-PDGFRα. 2013 2
20 22447844 Cyclin-dependent kinase 7/9 inhibitor SNS-032 abrogates FIP1-like-1 platelet-derived growth factor receptor α and bcr-abl oncogene addiction in malignant hematologic cells. 2012 Apr 1 1
21 22745105 Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors. 2012 Aug 15 4
22 20518073 Imatinib targets PDGF signaling in melanoma and host smooth muscle neighboring cells. 2010 Oct 1 3
23 20523072 FIP1L1/PDGFR alpha-associated systemic mastocytosis. 2010 1
24 20621681 Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. 2010 Sep 1
25 18568034 Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. 2008 Jul 2
26 17999742 Targeting stromal cells for the treatment of platelet-derived growth factor C-induced hepatocellular carcinogenesis. 2007 Nov 1
27 15928335 PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib. 2005 Aug 10 5
28 15009722 Imatinib mesylate inhibits platelet-derived growth factor receptor phosphorylation of melanoma cells but does not affect tumorigenicity in vivo. 2004 Feb 1
29 15221957 Different inhibitory effect of imatinib on phosphorylation of mitogen-activated protein kinase and Akt and on proliferation in cells expressing different types of mutant platelet-derived growth factor receptor-alpha. 2004 Sep 1 8
30 12781364 PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease. 2003 May 4
31 12808148 Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome. 2003 Jun 24 2
32 12949711 Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors. 2003 Sep 2
33 14695158 Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. 2003 Dec 15 1
34 12429650 Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571. 2002 Nov 1