ponatinib

fms related receptor tyrosine kinase 3 ; Homo sapiens







7 Article(s)
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1 32095692 Nicotinamide-Ponatinib Analogues as Potent Anti-CML and Anti-AML Compounds. 2020 Feb 18 1
2 33194747 Emergence of BCR-ABL1 Fusion in AML Post-FLT3 Inhibitor-Based Therapy: A Potentially Targetable Mechanism of Resistance - A Case Series. 2020 1
3 25053825 BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD. 2014 Oct 2
4 23430109 Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD. 2013 Apr 18 4
5 22409268 Ponatinib may overcome resistance of FLT3-ITD harbouring additional point mutations, notably the previously refractory F691I mutation. 2012 May 7
6 22778153 The novel BCR-ABL and FLT3 inhibitor ponatinib is a potent inhibitor of the MDR-associated ATP-binding cassette transporter ABCG2. 2012 Sep 2
7 21482694 Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies. 2011 Jun 6