111 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
101 | 23714533 | The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia. | 2013 | 4 |
102 | 23967177 | The FLT3 inhibitor quizartinib inhibits ABCG2 at pharmacologically relevant concentrations, with implications for both chemosensitization and adverse drug interactions. | 2013 | 5 |
103 | 23998902 | The E3 ubiquitin ligase TRAF2 can contribute to TNF-α resistance in FLT3-ITD-positive AML cells. | 2013 Nov | 2 |
104 | 24002496 | Phase I study of quizartinib administered daily to patients with relapsed or refractory acute myeloid leukemia irrespective of FMS-like tyrosine kinase 3-internal tandem duplication status. | 2013 Oct 10 | 2 |
105 | 24070241 | The role of quizartinib in the treatment of acute myeloid leukemia. | 2013 Dec | 5 |
106 | 22504184 | Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia. | 2012 Apr 15 | 3 |
107 | 22875611 | The N676D and G697R mutations in the kinase domain of FLT3 confer resistance to the inhibitor AC220. | 2012 Nov | 1 |
108 | 23012328 | Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML. | 2012 Nov 15 | 3 |
109 | 21895538 | The clinical development of FLT3 inhibitors in acute myeloid leukemia. | 2011 Oct | 2 |
110 | 19654408 | AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). | 2009 Oct 1 | 1 |
111 | 19754199 | Identification of N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride (AC220), a uniquely potent, selective, and efficacious FMS-like tyrosine kinase-3 (FLT3) inhibitor. | 2009 Dec 10 | 2 |