Imatinib Mesylate

CD34 molecule ; Homo sapiens







77 Article(s)
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51 19855080 Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib. 2009 Dec 10 1
52 19934315 Imatinib mesylate induces cisplatin hypersensitivity in Bcr-Abl+ cells by differential modulation of p53 transcriptional and proapoptotic activity. 2009 Dec 15 1
53 17690698 CD34+/Ph+ cells are still detectable in chronic myeloid leukemia patients with sustained and prolonged complete cytogenetic remission during treatment with imatinib mesylate. 2008 Feb 1
54 17349636 Upregulation of the TGFbeta signalling pathway by Bcr-Abl: implications for haemopoietic cell growth and chronic myeloid leukaemia. 2007 Apr 3 1
55 17376172 Total CD34+ cells per 10 HPF in bone marrow trephines of patients with chronic myeloid leukaemia correlates with probability of complete cytogenetic response following imatinib treatment. 2007 May 1
56 17538248 Imatinib and nilotinib induce apoptosis of chronic myeloid leukemia cells through a Bim-dependant pathway modulated by cytokines. 2007 Jun 1
57 17554385 The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells. 2007 Aug 1
58 17717597 FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia. 2007 Sep 4
59 18024285 [STI571 enhances the effect of arsenic trioxide and Velcade on bcr/abl+-CD34+ cell proliferation and apoptosis]. 2007 Nov 5
60 16572205 BCR-ABL activity and its response to drugs can be determined in CD34+ CML stem cells by CrkL phosphorylation status using flow cytometry. 2006 Jun 1
61 16670264 A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation. 2006 Sep 1 1
62 15345592 Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment. 2005 Mar 1 3
63 15618956 Gene expression profiling of Philadelphia chromosome (Ph)-negative CD34+ hematopoietic stem and progenitor cells of patients with Ph-positive CML in major molecular remission during therapy with imatinib. 2005 Mar 1
64 15805265 p210BCR-ABL inhibits SDF-1 chemotactic response via alteration of CXCR4 signaling and down-regulation of CXCR4 expression. 2005 Apr 1 1
65 15815728 Nonproliferating CML CD34+ progenitors are resistant to apoptosis induced by a wide range of proapoptotic stimuli. 2005 Jun 1
66 15933063 Analysis of total phosphotyrosine levels in CD34+ cells from CML patients to predict the response to imatinib mesylate treatment. 2005 Jun 15 1
67 15958710 Effect of tyrosine kinase inhibition using imatinib on normal lymphohematopoietic cells. 2005 Jun 1
68 16015388 Synergistic interactions between MEK1/2 and histone deacetylase inhibitors in BCR/ABL+ human leukemia cells. 2005 Sep 1
69 16107888 Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib. 2005 Oct 1
70 16204063 Bcr-Abl expression levels determine the rate of development of resistance to imatinib mesylate in chronic myeloid leukemia. 2005 Oct 1 1
71 16219536 Enhanced CML stem cell elimination in vitro by bryostatin priming with imatinib mesylate. 2005 Oct 1
72 12969987 Inhibitory effect of imatinib on normal progenitor cells in vitro. 2004 Jan 15 2
73 14504105 Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells. 2004 Jan 15 2
74 14715630 Imatinib and plasmacytoid dendritic cell function in patients with chronic myeloid leukemia. 2004 Jun 15 2
75 15124675 Imatinib mesylate selectively influences the cellular metabolism of cytarabine in BCR/ABL negative leukemia cell lines and normal CD34+ progenitor cells. 2004 2
76 11986238 Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation. 2002 May 15 2
77 11746976 Transcription factor BACH2 is transcriptionally regulated by the BCR/ABL oncogene. 2001 Dec 1