Simvastatin

CD4 molecule ; Homo sapiens







8 Article(s)
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Pub. Year
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1 34687147 Inhibition of mevalonate metabolism by statins augments the immunoregulatory phenotype of vascular endothelial cells and inhibits the costimulation of CD4+ T cells. 2022 Mar 1
2 34321273 Statins act as transient type I interferon inhibitors to enable the antitumor activity of modified vaccinia Ankara viral vectors. 2021 Jul 1
3 31269241 Statins can suppress DC-mediated Th2 responses through the repression of OX40-ligand and CCL17 expression. 2019 Nov 1
4 24159421 Statin Modulation of Human T-Cell Proliferation, IL-1β and IL-17 Production, and IFN-γ T Cell Expression: Synergy with Conventional Immunosuppressive Agents. 2013 1
5 18453621 Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. 2008 May 15 3
6 18484192 Statins' immunomodulatory potential against Th17 cell-mediated autoimmune response. 2008 2
7 17520029 Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease infection of R5 versus X4 HIV-1. 2007 May 23 1
8 17929126 Effects of low-dosage simvastatin on rheumatoid arthritis through reduction of Th1/Th2 and CD4/CD8 ratios. 2007 3