| 1 |
19318319 | Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis. | 2009 Mar |
1 |
| 2 |
16803610 | Sustained virological response to peginterferon plus ribavirin in chronic hepatitis C genotype 1 patients is associated with a persistent Th1 immune response. | 2006 Jul 1 |
2 |
| 3 |
15147365 | Immunoregulatory defects of V alpha 24V+ beta 11+ NKT cells in development of Wegener's granulomatosis and relapsing polychondritis. | 2004 Jun |
1 |
| 4 |
13679604 | The di-leucine motif in the cytoplasmic tail of CD4 is not required for binding to human immunodeficiency virus type 1 Nef, but is critical for CD4 down-modulation. | 2003 Oct |
3 |
| 5 |
11835689 | Phorbol esters and cAMP differentially regulate the expression of CD4 and CD8 in human thymocytes. | 2002 |
2 |
| 6 |
11997392 | A constitutively nuclear form of NFATx shows efficient transactivation activity and induces differentiation of CD4(+)CD8(+) T cells. | 2002 Jul 12 |
2 |
| 7 |
11506744 | Identification of IFN-gamma-producing CD4+ T cells following PMA stimulation. | 2001 Jul |
1 |
| 8 |
10941932 | Differential level in co-down-modulation of CD4 and CXCR4 primed by HIV-1 gp120 in response to phorbol ester, PMA, among HIV-1 isolates. | 2000 |
1 |
| 9 |
10963813 | Induction of NK1.1(+) alpha beta TCR(+) T cells by bypassing TCR signals in ZAP-70 deficient mice. | 2000 Jul 3 |
1 |
| 10 |
10069811 | Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation. | 1999 Mar |
2 |
| 11 |
10318836 | Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms. | 1999 May 14 |
2 |
| 12 |
9636688 | A humanised therapeutic CD4 mAb inhibits TCR-induced IL-2, IL-4, and IL-10 secretion and expression of CD25, CD40L, and CD69. | 1998 May 1 |
1 |
| 13 |
9701025 | Differential CD4-dependent inhibition of JNK but not Erk-2 activities in human naive and memory CD4+ T cell populations. | 1998 Jul |
5 |
| 14 |
9718374 | Differential regulation of CXCR4 and CCR5 endocytosis. | 1998 Sep |
1 |
| 15 |
9464820 | Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells. | 1997 Dec |
1 |
| 16 |
14646564 | HIV-1 envelope glycoproteins-mediated apoptosis is regulated by CD4 dependent and independent mechanisms. | 1997 |
2 |
| 17 |
8548832 | IL-2-resistant hyporesponsiveness induced by CD4 mAbs in OKT3-activated human T cells is reversed by CD45RA triggering. | 1996 Jan 10 |
1 |
| 18 |
8627671 | Inhibition of Nef- and phorbol ester-induced CD4 degradation by macrolide antibiotics. | 1996 Mar |
1 |
| 19 |
8849450 | Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines. | 1996 Oct 25 |
1 |
| 20 |
7545243 | Phorbol ester-induced down modulation of tailless CD4 receptors requires prior binding of gp120 and suggests a role for accessory molecules. | 1995 Oct |
1 |
| 21 |
7857297 | Signal transduction in SF9 insect cells: endocytosis of recombinant CD4 after phorbol ester treatment. | 1995 Feb 6 |
1 |
| 22 |
8574146 | N-acetylcysteine (NAC) enhances interleukin-2 but suppresses interleukin-4 secretion from normal and HIV+ CD4+ T-cells. | 1995 |
1 |
| 23 |
7906314 | The phorbol ester phorbol myristate acetate inhibits human immunodeficiency virus type 1 envelope-mediated fusion by modulating an accessory component(s) in CD4-expressing cells. | 1994 Mar |
2 |
| 24 |
7947460 | IL-12 transiently induces IFN-gamma transcription and protein synthesis in human CD4+ allergen-specific Th2 T cell clones. | 1994 Jul |
1 |
| 25 |
8376930 | Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting. | 1993 Oct 1 |
6 |
| 26 |
8500265 | The impaired in vitro production of interleukin-2 in HIV infection is negatively correlated to the number of circulating CD4+DR+ T cells and is reversed by allowing T cells to rest in culture: arguments for in vivo CD4+ T cell activation. | 1993 Jun |
2 |
| 27 |
8517797 | Phagocytosis reduces HIV-1 production in human monocytes/macrophages infected in vitro. | 1993 |
1 |
| 28 |
1280163 | A lymphocyte-specific protein tyrosine kinase, p56lck, regulates the PMA-induced internalization of CD4. | 1992 Nov 17 |
1 |
| 29 |
1283470 | Phorbol ester induces down-regulation of CD4 molecule expression and resistance to in vitro infection by HIV1. | 1992 Dec |
1 |
| 30 |
1310988 | Inhibition of T cell antigen receptor-dependent phosphorylation of CD4 in human immunodeficiency virus type 1 infected cells. | 1992 Feb 25 |
2 |
| 31 |
1349321 | A protein kinase C-activating phorbol ester accelerates the T cell antigen receptor-stimulated phosphatidylinositol cycle in normal human CD4+ T cells. | 1992 May 1 |
1 |
| 32 |
1406695 | A Raf-1-related p110 polypeptide associates with the CD4-p56lck complex in T cells. | 1992 Nov |
2 |
| 33 |
1502168 | Disruption of the CD4-p56lck complex is required for rapid internalization of CD4. | 1992 Aug 15 |
2 |
| 34 |
1527011 | Degradation of CD4 following phorbol-induced internalization in human T lymphocytes. Evidence for distinct endocytic routing of CD4 and CD3. | 1992 Sep 15 |
1 |
| 35 |
1612121 | Internalization, lysosomal degradation and new synthesis of surface membrane CD4 in phorbol ester-activated T-lymphocytes and U-937 cells. | 1992 Jul |
4 |
| 36 |
1628656 | CD4 gene transcription is transiently repressed during differentiation of myeloid cells to macrophage-like cells. | 1992 Jul 1 |
8 |
| 37 |
1660001 | A novel conformationally restricted protein kinase C inhibitor, Ro 31-8425, inhibits human neutrophil superoxide generation by soluble, particulate and post-receptor stimuli. | 1991 Nov 18 |
1 |
| 38 |
1671352 | Autonomous roles for the cytoplasmic domains of the CD2 and CD4 T cell surface antigens. | 1991 Feb |
2 |
| 39 |
1707923 | Phorbol esters down-regulate transcription and translation of the CD4 gene. | 1991 Apr 15 |
1 |
| 40 |
1836455 | Bispecific antibody-directed antitumor activity of human CD4+ helper/killer T cells induced by anti-CD3 monoclonal antibody plus interleukin 2. | 1991 Nov |
1 |
| 41 |
1871966 | Synthetic peptides from the principal neutralizing domain of human immunodeficiency virus type 1 (HIV-1) enhance HIV-1 infection through a CD4-dependent mechanism. | 1991 Sep |
1 |
| 42 |
2013157 | Myocyte injury and contraction abnormalities produced by cytotoxic T lymphocytes. | 1991 Apr |
1 |
| 43 |
2105883 | Structural features of the cytoplasmic region of CD4 required for internalization. | 1990 Feb |
1 |
| 44 |
2109010 | Phorbol myristate acetate-induced down-modulation of CD4 is dependent on calmodulin and intracellular calcium. | 1990 Apr 15 |
1 |
| 45 |
2141572 | The activation of protein kinase C is not necessary for the monoclonal antibody-induced modulation of CD3 and CD4 antigens. | 1990 May |
1 |
| 46 |
2265712 | Surface membrane CD4 turnover in phorbol ester stimulated T-lymphocytes. Evidence of degradation and increased synthesis. | 1990 Dec 10 |
2 |
| 47 |
2292458 | Lymphocyte mitogenesis and CD4 modulation induced by different phorbol esters: comparative studies. | 1990 |
3 |
| 48 |
2966682 | Envelope glycoprotein of HIV induces interference and cytolysis resistance in CD4+ cells: mechanism for persistence in AIDS. | 1988 May 6 |
1 |
| 49 |
3259607 | Altered expression of lymphocyte differentiation antigens on phorbol ester-activated CD4+8+ T cells. | 1988 Jun 15 |
2 |
| 50 |
3261635 | HIV infection does not require endocytosis of its receptor, CD4. | 1988 Sep 9 |
2 |