Lysine

immunoglobulin heavy diversity 1-7 ; Homo sapiens







6 Article(s)
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Title
Pub. Year
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1 28088282 Conjugation site analysis of antibody-drug-conjugates (ADCs) by signature ion fingerprinting and normalized area quantitation approach using nano-liquid chromatography coupled to high resolution mass spectrometry. 2017 Feb 22 7
2 28131055 LC-MS/MS method for the simultaneous determination of Lys-MCC-DM1, MCC-DM1 and DM1 as potential intracellular catabolites of the antibody-drug conjugate trastuzumab emtansine (T-DM1). 2017 Apr 15 1
3 28388007 Aberrant intracellular metabolism of T-DM1 confers T-DM1 resistance in human epidermal growth factor receptor 2-positive gastric cancer cells. 2017 Jul 2
4 25694334 Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate. 2015 Aug 1
5 21391620 Design of antibody-maytansinoid conjugates allows for efficient detoxification via liver metabolism. 2011 Apr 20 1
6 20698491 Physicochemical stability of the antibody-drug conjugate Trastuzumab-DM1: changes due to modification and conjugation processes. 2010 Sep 15 3