resiniferatoxin

transient receptor potential cation channel subfamily V member 1 ; Homo sapiens







92 Article(s)
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1 35350319 Hydrogel-Mediated Release of TRPV1 Modulators to Fine Tune Osteoclastogenesis. 2022 Mar 22 5
2 35610228 Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. 2022 May 24 4
3 34421597 Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials. 2021 2
4 34504955 Lipid-dependent sequential allosteric activation of heat-sensing TRPV1 channels by anchor-stereoselective "hot" vanilloid compounds and analogs. 2021 Dec 1
5 31757360 The Contribution of the Ankyrin Repeat Domain of TRPV1 as a Thermal Module. 2020 Feb 25 1
6 31846438 Cardiac TRPV1 afferent signaling promotes arrhythmogenic ventricular remodeling after myocardial infarction. 2020 Feb 13 3
7 32292906 The role of afferent pulmonary innervation in ARDS associated with COVID-19 and potential use of resiniferatoxin to improve prognosis: A review. 2020 Mar 4
8 30644819 Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity. 2019 Jan 15 2
9 30761069 Transient Receptor Potential Vanilloid 1 Modulates Central Inflammation in Multiple Sclerosis. 2019 6
10 31263706 Multifunctional TRPV1 Ion Channels in Physiology and Pathology with Focus on the Brain, Vasculature, and Some Visceral Systems. 2019 1
11 31399015 Agents in early development for treatment of bladder dysfunction - promise of drugs acting at TRP channels? 2019 Sep 1
12 29452097 Stimulation of TRPV1 channels activates the AP-1 transcription factor. 2018 Apr 1
13 29553496 Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1. 2018 Feb 13 4
14 29746471 Atypical pharmacology of schistosome TRPA1-like ion channels. 2018 May 1
15 27976413 Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists. 2017 Jul 1
16 28626428 Molecular Surgery Concept from Bench to Bedside: A Focus on TRPV1+ Pain-Sensing Neurons. 2017 2
17 28892388 Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1). 2017 Oct 12 2
18 28945920 Human podocytes express functional thermosensitive TRPV channels. 2017 Dec 1
19 29041773 Total Synthesis of Resiniferatoxin Enabled by Radical-Mediated Three-Component Coupling and 7-endo Cyclization. 2017 Nov 15 1
20 29129206 Differential cytotoxicity and intracellular calcium-signalling following activation of the calcium-permeable ion channels TRPV1 and TRPA1. 2017 Dec 1
21 26482371 Netrin-1 Contributes to Myelinated Afferent Fiber Sprouting and Neuropathic Pain. 2016 Oct 5
22 26719417 Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin. 2016 Jan 12 3
23 26884754 Integrating TRPV1 Receptor Function with Capsaicin Psychophysics. 2016 1
24 27180305 Activation of endogenous TRPV1 fails to induce overstimulation-based cytotoxicity in breast and prostate cancer cells but not in pain-sensing neurons. 2016 Aug 2
25 27339229 Competitive inhibition of TRPV1-calmodulin interaction by vanilloids. 2016 Aug 1
26 27529257 Resiniferatoxin: The Evolution of the "Molecular Scalpel" for Chronic Pain Relief. 2016 Aug 11 4
27 27563913 TRPV1: A Target for Rational Drug Design. 2016 Aug 23 4
28 27606946 Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study. 2016 2
29 25568328 Role of the outer pore domain in transient receptor potential vanilloid 1 dynamic permeability to large cations. 2015 Feb 27 2
30 25903376 Functional expression of TRPV channels in T cells and their implications in immune regulation. 2015 Jul 1
31 26411767 TRPV1 Channel: A Potential Drug Target for Treating Epilepsy. 2015 1
32 24321344 Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands. 2014 Jan 1 2
33 24794110 α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists. 2014 Jun 15 1
34 24838827 Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration. 2014 Sep 2
35 25077949 Intraganglionic signaling as a novel nasal-meningeal pathway for TRPA1-dependent trigeminovascular activation by inhaled environmental irritants. 2014 4
36 23139219 Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. 2013 Jan 15 1
37 23352977 Inhibition by capsaicin and its related vanilloids of compound action potentials in frog sciatic nerves. 2013 Mar 14 2
38 23468922 The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells. 2013 4
39 26779292 Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine. 2013 1
40 22262838 Intact microtubules preserve transient receptor potential vanilloid 1 (TRPV1) functionality through receptor binding. 2012 Mar 2 1
41 22493457 Agonist- and Ca2+-dependent desensitization of TRPV1 channel targets the receptor to lysosomes for degradation. 2012 Jun 1 1
42 21237298 The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy. 2011 May 1 1
43 21276877 TRPV1 channels in the nucleus of the solitary tract mediate thermal prolongation of the LCR in decerebrate piglets. 2011 Apr 30 1
44 21620567 Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity. 2011 Sep 2
45 21671878 Therapeutic targeting of TRPV1 by resiniferatoxin, from preclinical studies to clinical trials. 2011 2
46 21671879 TRPV1 activation is not an all-or-none event: TRPV1 partial agonism/antagonism and its regulatory modulation. 2011 2
47 20230457 Transient receptor potential channels in pain and inflammation: therapeutic opportunities. 2010 May-Jun 1
48 20501335 Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways. 2010 Oct 2
49 20884761 Endocannabinoid-dependent LTD in a nociceptive synapse requires activation of a presynaptic TRPV-like receptor. 2010 Nov 1
50 19059369 The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. 2009 Mar 2