Hydroxamic Acids

histone deacetylase 6 ; Homo sapiens







20 Article(s)
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1 35630812 Design, Synthesis, Bioactivity Evaluation, Crystal Structures, and In Silico Studies of New α-Amino Amide Derivatives as Potential Histone Deacetylase 6 Inhibitors. 2022 May 22 1
2 33035922 Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors. 2021 Jan 1 1
3 33759126 Fragment-Based Drug Design of Selective HDAC6 Inhibitors. 2021 1
4 34153811 Novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors to suppress tumor metastasis and invasion in vitro and in vivo. 2021 Sep 1
5 34187263 Molecular design, synthesis and in vitro biological evaluation of thienopyrimidine-hydroxamic acids as chimeric kinase HDAC inhibitors: a challenging approach to combat cancer. 2021 Dec 1
6 34517222 Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease. 2021 Dec 5 1
7 34648295 Discovery of a Series of Hydroxamic Acid-Based Microtubule Destabilizing Agents with Potent Antitumor Activity. 2021 Oct 28 1
8 32591593 Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines. 2020 Jun 26 1
9 31072216 Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma. 2019 Dec 2
10 29133060 Recent advances in the discovery of potent and selective HDAC6 inhibitors. 2018 Jan 1 1
11 29500130 Design, synthesis and biological evaluation of novel hydroxamic acid based histone deacetylase 6 selective inhibitors bearing phenylpyrazol scaffold as surface recognition motif. 2018 May 1 2
12 28746804 A Linker for the Solid-Phase Synthesis of Hydroxamic Acids and Identification of HDAC6 Inhibitors. 2017 Oct 9 1
13 27759399 Metal-Free Direct Amidation of Naphthoquinones Using Hydroxamic Acids as an Amide Source: Application in the Synthesis of an HDAC6 Inhibitor. 2016 Nov 4 1
14 25937017 Pyridine hydroxamic acids are specific anti-HCV agents affecting HDAC6. 2015 Jun 1 2
15 24565573 4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors. 2014 Apr 9 1
16 23368884 Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif. 2013 Feb 28 2
17 24023063 Development of a histone deacetylase 6 inhibitor and its biological effects. 2013 Sep 24 1
18 19090524 Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors. 2009 Feb 1
19 18054239 Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs). 2008 Feb 15 2
20 17699868 Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90. 2007 Aug 15 2