| 1 |
32235053 | The phasor FLIM method reveals a link between a change in energy metabolism and mHtt protein spread in healthy Mammalian cells when co-cultured with Huntington diseased cells. | 2021 Jan 11 |
2 |
| 2 |
32995988 | DYNLT1 gene expression is downregulated in whole blood of patients at different Huntington's disease stages. | 2021 May |
1 |
| 3 |
33070471 | Altered third-party punishment in Huntington's disease: A study using neuroeconomic games. | 2021 Jan |
1 |
| 4 |
33827396 | Cardio-Vascular Heat Shock Protein (cvHsp, HspB7), an Unusual Representative of Small Heat Shock Protein Family. | 2021 Jan |
1 |
| 5 |
33920936 | Emerging Roles of Exosomes in Huntington's Disease. | 2021 Apr 15 |
1 |
| 6 |
34201610 | Membrane Interactions Accelerate the Self-Aggregation of Huntingtin Exon 1 Fragments in a Polyglutamine Length-Dependent Manner. | 2021 Jun 23 |
1 |
| 7 |
34831058 | The Cytotoxicity and Clearance of Mutant Huntingtin and Other Misfolded Proteins. | 2021 Oct 21 |
1 |
| 8 |
34880419 | Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1. | 2021 Dec 8 |
3 |
| 9 |
32341997 | Live-Cell Imaging and Quantification of PolyQ Aggregates by Stimulated Raman Scattering of Selective Deuterium Labeling. | 2020 Apr 22 |
1 |
| 10 |
32402249 | Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins. | 2020 Jul 7 |
1 |
| 11 |
33224521 | New developments in Huntington's disease and other triplet repeat diseases: DNA repair turns to the dark side. | 2020 Dec |
2 |
| 12 |
30672003 | Structural insights into the aggregation mechanism of huntingtin exon 1 protein fragment with different polyQ-lengths. | 2019 Jun |
1 |
| 13 |
30842263 | Design and characterization of mutant and wildtype huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems. | 2019 Apr 26 |
1 |
| 14 |
31226569 | MnFe2O4 nanoparticles accelerate the clearance of mutant huntingtin selectively through ubiquitin-proteasome system. | 2019 Sep |
2 |
| 15 |
31297710 | Quality Control in Huntington's Disease: a Therapeutic Target. | 2019 Oct |
2 |
| 16 |
31398342 | CAG Repeat Not Polyglutamine Length Determines Timing of Huntington's Disease Onset. | 2019 Aug 8 |
1 |
| 17 |
29359503 | A General Strategy to Access Structural Information at Atomic Resolution in Polyglutamine Homorepeats. | 2018 Mar 26 |
2 |
| 18 |
29377621 | Potassium channel dysfunction in neurons and astrocytes in Huntington's disease. | 2018 Apr |
2 |
| 19 |
29601786 | Self-assembly of Mutant Huntingtin Exon-1 Fragments into Large Complex Fibrillar Structures Involves Nucleated Branching. | 2018 Jun 8 |
1 |
| 20 |
30279700 | SUMO-Targeted Ubiquitin Ligases (STUbLs) Reduce the Toxicity and Abnormal Transcriptional Activity Associated With a Mutant, Aggregation-Prone Fragment of Huntingtin. | 2018 |
1 |
| 21 |
27514446 | Mitochondrial fragmentation in neuronal degeneration: Toward an understanding of HD striatal susceptibility. | 2017 Feb 19 |
2 |
| 22 |
28674979 | Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets. | 2017 |
1 |
| 23 |
28968242 | Huntington's Disease and Diabetes: Chronological Sequence of its Association. | 2017 |
1 |
| 24 |
26350150 | Delayed emergence of subdiffraction-sized mutant huntingtin fibrils following inclusion body formation. | 2016 Jan |
1 |
| 25 |
26601664 | Inhibition of Early Biochemical Defects in Prodromal Huntington's Disease by Simultaneous Activation of Nrf2 and Elevation of Multiple Micronutrients. | 2016 |
1 |
| 26 |
26846325 | Reduced Mitochondrial Function in Human Huntington Disease Lymphoblasts is Not Due to Alterations in Cardiolipin Metabolism or Mitochondrial Supercomplex Assembly. | 2016 May |
1 |
| 27 |
26863614 | Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells. | 2016 |
1 |
| 28 |
24048953 | Large Animal Models of Huntington's Disease. | 2015 |
1 |
| 29 |
25687118 | Expansion of CAG triplet repeats by human DNA polymerases λ and β in vitro, is regulated by flap endonuclease 1 and DNA ligase 1. | 2015 May |
1 |
| 30 |
25761110 | Enhanced neuronal glucose transporter expression reveals metabolic choice in a HD Drosophila model. | 2015 |
1 |
| 31 |
25995452 | Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography. | 2015 Jul 10 |
1 |
| 32 |
26195796 | Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase. | 2015 Aug 4 |
1 |
| 33 |
26210848 | Association of status redox with demographic, clinical and imaging parameters in patients with Huntington's disease. | 2015 Dec |
3 |
| 34 |
26673834 | A protein polymerization cascade mediates toxicity of non-pathological human huntingtin in yeast. | 2015 Dec 17 |
2 |
| 35 |
24184605 | Nucleolar dysfunction in Huntington's disease. | 2014 Jun |
2 |
| 36 |
24415136 | Atomistic mechanisms of huntingtin N-terminal fragment insertion on a phospholipid bilayer revealed by molecular dynamics simulations. | 2014 Jul |
1 |
| 37 |
24968783 | The role of dopamine in Huntington's disease. | 2014 |
1 |
| 38 |
25316320 | Proteomics of Huntington's disease-affected human embryonic stem cells reveals an evolving pathology involving mitochondrial dysfunction and metabolic disturbances. | 2014 Dec 5 |
2 |
| 39 |
25358787 | Reversal of cellular phenotypes in neural cells derived from Huntington's disease monkey-induced pluripotent stem cells. | 2014 Oct 14 |
2 |
| 40 |
25723022 | [Huntington's disease: cellular and molecular basis of pathology]. | 2014 Jul-Aug |
2 |
| 41 |
23423362 | Role of cerebral cortex in the neuropathology of Huntington's disease. | 2013 |
1 |
| 42 |
23612654 | The unresolved puzzle why alanine extensions cause disease. | 2013 Aug |
1 |
| 43 |
23819039 | Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis. | 2013 Apr |
1 |
| 44 |
23847583 | A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington's Disease Gene Mutation. | 2013 |
1 |
| 45 |
24006238 | Epigenetic mechanisms of neurodegeneration in Huntington's disease. | 2013 Oct |
1 |
| 46 |
24330821 | Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease. | 2013 Dec 11 |
1 |
| 47 |
25063429 | A transgenic minipig model of Huntington's Disease. | 2013 |
1 |
| 48 |
22052286 | An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors. | 2012 Feb 1 |
1 |
| 49 |
22200539 | Protein aggregates in Huntington's disease. | 2012 Nov |
1 |
| 50 |
22773688 | Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease. | 2012 Oct |
2 |