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32798290 | Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system. | 2021 May |
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33091458 | The orexin (hypocretin) neuropeptide system is a target for novel therapeutics to treat cocaine use disorder with alcohol coabuse. | 2021 Feb 1 |
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33708078 | Cocaine-Seeking Behavior Induced by Orexin A Administration in the Posterior Paraventricular Nucleus of the Thalamus Is Not Long-Lasting: Neuroadaptation of the Orexin System During Cocaine Abstinence. | 2021 |
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34318655 | Blockade of corticotropin-releasing factor receptor 1 in the central amygdala prevents cocaine-seeking behaviour induced by orexin-A administered to the posterior paraventricular nucleus of the thalamus in male rats. | 2021 Jul 28 |
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30219208 | Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats. | 2019 Jun 1 |
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31112988 | The role of orexin-1 receptor signaling in demand for the opioid fentanyl. | 2019 Sep |
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27558790 | Differential role of hypothalamic orexin/hypocretin neurons in reward seeking motivated by cocaine versus palatable food. | 2018 Jan |
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28419646 | Suvorexant, an orexin/hypocretin receptor antagonist, attenuates motivational and hedonic properties of cocaine. | 2018 Jan |
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29703996 | Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats. | 2018 Nov |
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29888304 | Early-life adversity facilitates acquisition of cocaine self-administration and induces persistent anhedonia. | 2018 Feb |
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27567312 | Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in Rats. | 2017 Apr 1 |
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26055195 | Activation of Hypocretin-1/Orexin-A Neurons Projecting to the Bed Nucleus of the Stria Terminalis and Paraventricular Nucleus Is Critical for Reinstatement of Alcohol Seeking by Neuropeptide S. | 2016 Mar 15 |
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27540003 | Orexin-A/Hypocretin-1 Mediates Cocaine-Seeking Behavior in the Posterior Paraventricular Nucleus of the Thalamus via Orexin/Hypocretin Receptor-2. | 2016 Nov |
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25754681 | Orexin-1 receptor signaling increases motivation for cocaine-associated cues. | 2015 May |
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25926444 | Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. | 2015 Apr 29 |
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22411428 | Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats. | 2013 Apr |
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22457508 | A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference. | 2012 Mar 28 |
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22971541 | Repeated orexin 1 receptor antagonism effects on cocaine seeking in rats. | 2012 Dec |
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21285875 | Orexin-1 receptor antagonist SB-334867 reduces the acquisition and expression of cocaine-conditioned reinforcement and the expression of amphetamine-conditioned reward. | 2011 Apr |
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19591850 | Orexin/hypocretin is necessary for context-driven cocaine-seeking. | 2010 Jan |
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19815001 | Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction. | 2010 Feb 16 |
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18655797 | Role of lateral hypothalamic orexin neurons in reward processing and addiction. | 2009 |
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19251246 | Reinstatement of cocaine seeking by hypocretin (orexin) in the ventral tegmental area: independence from the local corticotropin-releasing factor network. | 2009 May 15 |
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19656173 | Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking. | 2009 Aug |
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19671464 | Orexin-1 receptor antagonism decreases ethanol consumption and preference selectively in high-ethanol--preferring Sprague--Dawley rats. | 2009 Aug |
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18436386 | Effects of cocaine place conditioning, chronic escalating-dose "binge" pattern cocaine administration and acute withdrawal on orexin/hypocretin and preprodynorphin gene expressions in lateral hypothalamus of Fischer and Sprague-Dawley rats. | 2008 Jun 2 |
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