acadesine

protein kinase AMP-activated catalytic subunit alpha 2 ; Homo sapiens







103 Article(s)
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51 21205922 Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway. 2011 Apr 1
52 21228273 Hyaluronan synthesis is inhibited by adenosine monophosphate-activated protein kinase through the regulation of HAS2 activity in human aortic smooth muscle cells. 2011 Mar 11 3
53 21464390 Inhibition of the AMP-activated protein kinase-α2 accentuates agonist-induced vascular smooth muscle contraction and high blood pressure in mice. 2011 May 1
54 21470048 Stimulation of cardiomyogenesis of embryonic stem cells by nitric oxide downstream of AMP-activated protein kinase and mTOR signaling pathways. 2011 Dec 2
55 21697647 Role of the energy sensor adenosine monophosphate-activated protein kinase in the regulation of immature gonadotropin-releasing hormone neuron migration. 2011 Nov 4
56 21944462 5-aminoimidazole-4-carboxamide riboside enhances effect of ionizing radiation in PC3 prostate cancer cells. 2011 Dec 1 1
57 19617399 AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells. 2010 Jun 1
58 20177150 Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts. 2010 Apr 30 4
59 20430871 The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase. 2010 Jul 4
60 20490918 A pharmacological activator of AMP-activated protein kinase protects hypoxic neurons in a concentration-dependent manner. 2010 Aug 1
61 20615388 AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-beta-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway. 2010 Oct 15 2
62 20652679 AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3). 2010 Nov 2
63 18756496 Involvement of AMP-activated protein kinase and p38 mitogen-activated protein kinase in 8-Cl-cAMP-induced growth inhibition. 2009 Jan 2
64 18798311 Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators. 2009 Jan 4
65 19299524 Oxidized metabolites of oltipraz exert cytoprotective effects against arachidonic acid through AMP-activated protein kinase-dependent cellular antioxidant effect and mitochondrial protection. 2009 Jun 1
66 19571378 Regulation of glyceraldehyde 3-phosphate dehydrogenase expression by metformin in HepG2 cells. 2009 Jul 1
67 19656961 AMP-activated protein kinase facilitates avian reovirus to induce mitogen-activated protein kinase (MAPK) p38 and MAPK kinase 3/6 signalling that is beneficial for virus replication. 2009 Dec 1
68 17615555 Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase. 2008 Feb 15 3
69 18174285 Adiponectin antagonizes stimulatory effect of tumor necrosis factor-alpha on vascular smooth muscle cell calcification: regulation of growth arrest-specific gene 6-mediated survival pathway by adenosine 5'-monophosphate-activated protein kinase. 2008 Apr 4
70 18195011 alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments. 2008 Mar 14 3
71 18248608 The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease. 2008 Jun 2
72 18405894 Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line. 2008 Jun 10 3
73 18406347 AM251 suppresses the viability of HepG2 cells through the AMPK (AMP-activated protein kinase)-JNK (c-Jun N-terminal kinase)-ATF3 (activating transcription factor 3) pathway. 2008 Jun 13 2
74 18671468 Acadesine, an adenosine-regulating agent with the potential for widespread indications. 2008 Aug 1
75 23489075 Advances in the development of AMPK-activating compounds. 2008 Oct 4
76 17179149 Inhibition of hepatic phosphatidylcholine synthesis by 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside is independent of AMP-activated protein kinase activation. 2007 Feb 16 4
77 17215282 AMPK-mediated inhibition of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus infection. 2007 Apr 2
78 17332500 Diverse cytopathologies in mitochondrial disease are caused by AMP-activated protein kinase signaling. 2007 May 1
79 17496363 The role of AMP kinase in diabetes. 2007 Mar 2
80 17669398 Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cells. 2007 Oct 1 3
81 16515522 AMP-activated protein kinase and type 2 diabetes. 2006 2
82 16731851 Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway. 2006 Jun 2
83 16943194 Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase. 2006 Oct 27 2
84 16985054 Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside. 2006 Sep 1
85 17065104 5 '-Amino-4-imidazolecarboxamide riboside induces apoptosis in human neuroblastoma cells via the mitochondrial pathway. 2006 2
86 15860681 AICAR and hyperosmotic stress increase insulin-stimulated glucose transport. 2005 Sep 1
87 16105857 Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase. 2005 Dec 4
88 15328001 Stimulators of AMP-activated protein kinase inhibit the respiratory burst in human neutrophils. 2004 Aug 27 1
89 15356065 AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females. 2004 Sep 1
90 15358229 AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms. 2004 Aug 13 1
91 12452797 5-Aminoimidazole-4-carboxamide riboside induces apoptosis in Jurkat cells, but the AMP-activated protein kinase is not involved. 2003 Mar 15 2
92 12522004 Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes. 2003 May 1 7
93 12546682 A possible role for AMP-activated protein kinase in exercise-induced glucose utilization: insights from humans and transgenic animals. 2003 Feb 4
94 12558800 A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway. 2003 Jan 2
95 12791703 Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells. 2003 Aug 22 1
96 12869384 Activation of AMP-activated protein kinase reduces cAMP-mediated epithelial chloride secretion. 2003 Nov 2
97 14597982 AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets. 2003 Nov 1
98 11756336 Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. 2002 Jan 4
99 12067722 Hepatic amino acid-dependent signaling is under the control of AMP-dependent protein kinase. 2002 Jun 19 2
100 12153572 Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes. 2002 Aug 1