acadesine

protein kinase AMP-activated catalytic subunit alpha 2 ; Homo sapiens







103 Article(s)
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1 35135451 Anti-cancer Effects of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside (AICAR) on Triple-negative Breast Cancer (TNBC) Cells: Mitochondrial Modulation as an Underlying Mechanism. 2022 2
2 35217431 SIRT3-AMPK signaling pathway as a protective target in endothelial dysfunction of early sepsis. 2022 May 1
3 35241643 miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD+/SIRT inactivation. 2022 Mar 4 1
4 35254586 AMP-activated kinase regulates porcine reproductive and respiratory syndrome virus infection in vitro. 2022 Apr 1
5 34042039 Highlighting the Protective or Degenerative Role of AMPK Activators in Dementia Experimental Models. 2021 1
6 34064363 AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review. 2021 May 4 7
7 34418237 Identification and function prediction of novel microRNAs in adenosine monophosphate activated protein kinase-activated Sertoli cells of immature boar. 2021 Dec 2
8 32561924 AMPK Activation by 5-Amino-4-Imidazole Carboxamide Riboside-1-β-D-Ribofuranoside Attenuates Alkali Injury-Induced Corneal Fibrosis. 2020 Jun 3 3
9 32588910 Skeletal muscle AMPK is not activated during 2 h of moderate intensity exercise at ∼65% V ̇ O 2 peak in endurance trained men. 2020 Sep 2
10 32913552 Heme oxygenase-1 enhances autophagy by modulating the AMPK/mTORC1 signaling pathway as a renoprotective mechanism to mitigate lead-induced nephrotoxicity. 2020 1
11 33362238 Acadesine suppresses TNF-α induced complement component 3 (C3), in retinal pigment epithelial (RPE) cells. 2020 3
12 29623826 Targeting AMPK in Diabetes and Diabetic Complications: Energy Homeostasis, Autophagy and Mitochondrial Health. 2019 1
13 29788824 Activation of AMPK in Human Placental Explants Impairs Mitochondrial Function and Cellular Metabolism. 2019 Apr 3
14 30724446 Nickel-induced VEGF expression via regulation of Akt, ERK1/2, NFκB, and AMPK pathways in H460 cells. 2019 May 1
15 30779249 Identification of microRNAs for regulating adenosine monophosphate-activated protein kinase expression in immature boar Sertoli cells in vitro. 2019 Apr 2
16 30847932 Theaflavin 3,3'-digallate reverses the downregulation of connexin 43 and autophagy induced by high glucose via AMPK activation in cardiomyocytes. 2019 Aug 1
17 30987073 AICAR Induces Apoptosis and Inhibits Migration and Invasion in Prostate Cancer Cells Through an AMPK/mTOR-Dependent Pathway. 2019 Apr 3 5
18 31008492 [Advances on the anti-inflammatory and protective effect of AMPK activators]. 2019 Apr 25 1
19 29460119 Curcumin Inhibits Monocyte Chemoattractant Protein-1 Expression in TNF-α induced Astrocytes Through AMPK Pathway. 2018 Apr 1
20 29982462 Pharmacological and physiological activation of AMPK improves the spliceopathy in DM1 mouse muscles. 2018 Oct 1 2
21 30021848 AMPK blunts chronic heart failure by inhibiting autophagy. 2018 Aug 31 1
22 30230919 Nucleosides block AICAR-stimulated activation of AMPK in skeletal muscle and cancer cells. 2018 Dec 1 4
23 30253109 AMPK activation by A-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes. 2018 Nov 1 2
24 30632675 Activation of AMPK alleviates cardiopulmonary bypass-induced cardiac injury via ameliorating acute cardiac glucose metabolic disorder. 2018 Dec 4
25 27847321 AICAR activates ER stress-dependent apoptosis in gallbladder cancer cells. 2017 Jan 8 4
26 28683454 Interactions of TLR4 and PPARγ, Dependent on AMPK Signalling Pathway Contribute to Anti-Inflammatory Effects of Vaccariae Hypaphorine in Endothelial Cells. 2017 2
27 28975042 5-Aminoimidazole-4-carboxamide ribonucleoside-induced autophagy flux during differentiation of monocytic leukemia cells. 2017 1
28 29247196 AICAR suppresses TNF-α-induced complement factor B in RPE cells. 2017 Dec 15 2
29 26997114 Glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation. 2016 Mar 21 2
30 27170207 AICAR Attenuates TNFα-Induced Inappropriate Secretion of Monocyte Chemoattractant Protein-1 and Adiponectin in 3T3-L1 Adipocytes. 2016 Dec 1 2
31 27521792 Adenosine monophosphate-activated protein kinase attenuates cardiomyocyte hypertrophy through regulation of FOXO3a/MAFbx signaling pathway. 2016 Sep 1
32 25778901 Sestrin2-AMPK activation protects mitochondrial function against glucose deprivation-induced cytotoxicity. 2015 Jul 2
33 26048992 AMP-activated Protein Kinase Suppresses Biosynthesis of Glucosylceramide by Reducing Intracellular Sugar Nucleotides. 2015 Jul 17 1
34 26391395 AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells. 2015 Nov 13 4
35 26483453 Dystrophin-glycoprotein complex regulates muscle nitric oxide production through mechanoregulation of AMPK signaling. 2015 Nov 3 1
36 24669186 Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. 2014 2
37 25842853 [High glucose promotes gap junctional communication in cultured neonatal cardiac fibroblasts via AMPK activation]. 2014 Jul-Aug 2
38 22751115 Role of AMPK in UVB-induced DNA damage repair and growth control. 2013 May 23 8
39 23018889 Involvement of Akt2/protein kinase B β (PKBβ) in the 8-Cl-cAMP-induced cancer cell growth inhibition. 2013 Apr 1
40 23225245 Mediation of AMP kinase in the increase of glucose uptake in L6 cells induced by activation of imidazoline I-2 receptors. 2013 May 2
41 23469683 Combination therapy with 5-amino-4-imidazolecarboxamide riboside and arsenic trioxide in acute myeloid leukemia cells involving AMPK/TSC2/mTOR pathway. 2013 Feb 6
42 23616923 Moderate excess of pyruvate augments osteoclastogenesis. 2013 Apr 15 1
43 23698161 Effects of eicosapentaenoic acid and docosahexaenoic acid on uncoupling protein 3 gene expression in C(2)C(12) muscle cells. 2013 May 21 1
44 23841933 AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons. 2013 Oct 1
45 23933835 Metformin action in human hepatocytes: coactivation of atypical protein kinase C alters 5'-AMP-activated protein kinase effects on lipogenic and gluconeogenic enzyme expression. 2013 Nov 2
46 21567395 AMP-activated protein kinase inhibits TGF-β-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300. 2012 Mar 2
47 21956774 Metabolomics of the effect of AMPK activation by AICAR on human umbilical vein endothelial cells. 2012 Jan 2
48 22074809 AMP-activated protein kinase and the control of smooth muscle cell hyperproliferation in vascular disease. 2012 Jan-Feb 3
49 22120676 Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. 2012 Feb 1 2
50 22740885 Effects of activation of AMPK on human breast cancer cell lines with different genetic backgrounds. 2012 Jan 1