Bezafibrate

peroxisome proliferator activated receptor alpha ; Homo sapiens







49 Article(s)
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Pub. Year
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1 34713454 Current and future treatment approaches for Barth syndrome. 2022 Jan 1
2 35563117 Functional and Structural Insights into Human PPARα/δ/γ Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate. 2022 Apr 25 1
3 33031833 Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial. 2021 Feb 2
4 33397369 Impact of peroxisome proliferator-activated receptor-α on diabetic cardiomyopathy. 2021 Jan 4 1
5 33498265 Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation. 2021 Jan 20 1
6 34335707 Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer. 2021 1
7 31713023 Clinical Management of Primary Biliary Cholangitis-Strategies and Evolving Trends. 2020 Oct 1
8 32629063 Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency. 2020 Aug 1
9 30315479 Bezafibrate Upregulates Mitochondrial Biogenesis and Influence Neural Differentiation of Human-Induced Pluripotent Stem Cells. 2019 Jun 3
10 30515714 The Role of Oxidative Stress and Bioenergetic Dysfunction in Sulfite Oxidase Deficiency: Insights from Animal Models. 2019 Feb 1
11 31163124 Effects of PPARs/20-HETE on the renal impairment under diabetic conditions. 2019 Sep 1 1
12 29928160 Update on New Drugs and Those in Development for the Treatment of Primary Biliary Cholangitis. 2018 Mar 1
13 30143538 PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8+ T Cells and Facilitates Anti-PD-1 Therapy. 2018 Nov 1
14 28097454 In vitro cytogenetic toxicity of bezafibrate in human peripheral blood lymphocytes. 2017 Aug 4
15 26467040 CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver. 2016 Jan 4
16 25134759 Bezafibrate, a peroxisome proliferator-activated receptor α agonist, decreases circulating CD14(+)CD16(+) monocytes in patients with type 2 diabetes. 2015 Feb 1
17 25539886 Fibrates protect against vascular endothelial dysfunction induced by paclitaxel and carboplatin chemotherapy for cancer patients: a pilot study. 2015 Aug 1
18 26333891 Ketogenic response to cotreatment with bezafibrate and medium chain triacylglycerols in healthy humans. 2015 Oct 2
19 23897856 Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis. 2014 Jan 1
20 24302581 PPARα activation can help prevent and treat non-small cell lung cancer. 2014 Jan 15 1
21 24606795 Mitochondrial biogenesis: pharmacological approaches. 2014 2
22 24950685 Effects of the environmental contaminants DEHP and TCDD on estradiol synthesis and aryl hydrocarbon receptor and peroxisome proliferator-activated receptor signalling in the human granulosa cell line KGN. 2014 Sep 1
23 24511666 Effectiveness of fenofibrate in comparison to bezafibrate for patients with asymptomatic primary biliary cirrhosis. 2013 Oct 1
24 22447153 Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibroblasts by inhibiting fatty acid elongation. 2012 Nov 1
25 22550474 Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo. 2012 2
26 19683050 Bezafibrate induces myotoxicity in human rhabdomyosarcoma cells via peroxisome proliferator-activated receptor alpha signaling. 2010 Feb 5
27 20404010 Bezafibrate mildly stimulates ketogenesis and fatty acid metabolism in hypertriglyceridemic subjects. 2010 Jul 2
28 21215149 [Oxidized low density lipoprotein and peroxisome proliferator-activated receptor α induced endogenous fibroblast growth factor 21 upregulation is protective against apoptosis in cardiac endothelial cells]. 2010 Dec 1
29 19124612 Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated receptor alpha-independent mechanism. 2009 Apr 2
30 19429239 15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells. 2009 May 22 1
31 19667161 Cross-talk between vitamin D receptor (VDR)- and peroxisome proliferator-activated receptor (PPAR)-signaling in melanoma cells. 2009 Sep 1
32 18211970 Activation of peroxisome proliferator-activated receptor pathway stimulates the mitochondrial respiratory chain and can correct deficiencies in patients' cells lacking its components. 2008 Apr 1
33 18230960 Optimal management of combined dyslipidemia: what have we behind statins monotherapy? 2008 1
34 17010686 PPAR agonists modulate human osteoclast formation and activity in vitro. 2007 Jan 1
35 15800711 Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors. 2005 1
36 15936983 The gene encoding the human ileal bile acid-binding protein (I-BABP) is regulated by peroxisome proliferator-activated receptors. 2005 Jun 15 1
37 15953354 Regulated expression of endothelial lipase by porcine brain capillary endothelial cells constituting the blood-brain barrier. 2005 Jul 1
38 16168052 Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons. 2005 Sep 16 1
39 16226225 Fibrates inhibit aldose reductase activity in the forward and reverse reactions. 2005 Nov 25 2
40 14523052 PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression. 2004 Jan 2
41 14982965 A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose levels and modifies lipoprotein profiles in KK-Ay mice. 2004 Jun 1
42 15258199 Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPARalpha-mediated redistribution of ABCB4. 2004 Oct 1
43 15521013 Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites. 2004 Nov 1
44 12595494 PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway. 2003 Mar 1
45 12759900 Differential effects of peroxisome proliferator-activated receptor activators on the mRNA levels of genes involved in lipid metabolism in primary human monocyte-derived macrophages. 2003 May 1
46 14615970 Bezafibrate induces a mitochondrial derangement in human cell lines: a PPAR-independent mechanism for a peroxisome proliferator. 2003 Nov 1
47 12000972 Peroxisome proliferator-activated receptor ligands as antiatherogenic agents: panacea or another Pandora's box? 2002 Jan 1
48 11422732 Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease. 2001 Jul 1
49 10753637 Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. 2000 Apr 13 1